TY - JOUR AU - Murdiyansah, Sandi AU - Citra Rasmi, Dewa Ayu AU - Mertha, I Gde PY - 2020/12/28 Y2 - 2024/03/29 TI - Centella asiatica Activities towards Staphylococcus aureus and Escherichia coli Growth JF - Jurnal Biologi Tropis JA - JBT VL - 20 IS - 3 SE - Articles DO - 10.29303/jbt.v20i3.1418 UR - https://jurnalfkip.unram.ac.id/index.php/JBT/article/view/1418 SP - 499-506 AB - <p><em>Centella asiatica </em>contains some secondary metabolic compounds, e.g. tannin, alkaloid, flavonoid, saponin, and triterpenoid, known as medicinal plants as well, one of which is as a anti-bacterial. The present study aimed at examining the activities of <em>Centella asiatica</em> extract towards the growth of <em>Staphylococcus aureus</em> and <em>Escherichia coli</em>. The extraction of C. asiatica was done by using ethanol and ethyl acetate solvents and the activity test employed seaweed diffusion. The hindrance power of <em>Centella asiatica</em> extract was tested in 30%, 50%, and 95% and the data were analyzed qualitatively with the standard issued by the Clinical and Laboratory Standard Institute and quantitatively with ANOVA. It shows that <em>Centella asiatica </em>extract in the ethyl acetate can hinder the growth of <em>Staphylococcus aureus</em> in the acetate concentration of 50% and 70% at the sensitive level and <em>Escherichia coli</em> at the intermediate level in the extract concentration of 50% and 70%. However, <em>Centella asiatica</em> activities in the ethanol solvent hinders the growth of either <em>Centella asiatica</em> or Escherichia coli with resistant category in the extract concentration of 70%. The hindrance power of <em>Centella asiatica</em> extract in ethyl acetate in the growth of <em>Staphylococcus aureus</em> is significantly more effective than that of <em>Centella asiatica</em> extract in the ethanol solvent</p> ER -