The Correlation between Iron and Protein Intake in the Hemoglobin Levels of the Faculty of Medicine Students, Unram
Authors
Rifana Cholidah , Emmy Amalia , Ario Danianto , Dyah Purnaning , Asti AnandaDOI:
10.29303/jbt.v26i1.11382Published:
2026-01-30Issue:
Vol. 26 No. 1 (2026): Januari-MaretKeywords:
Anemia, Medical student, Mataram, Iron, ProteinArticles
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Abstract
naemia is a global burden disease that mostly occurs in the reproductive age. About 31.2% of women of reproductive age (15-49 years) have anaemia. This condition may affect oxygen transport in the body and interfere with some bodily functions. Several factors may induce anaemia; iron deficiency is one of them. An amount of iron and protein intake may contribute to haemoglobin levels. This study aims to determine the correlation between iron and protein intake and haemoglobin levels among students in the Faculty of Medicine at the University of Mataram. This is an observational analytic study using cross-sectional methods that includes students aged 17-20 years old. Data is taken in May–June 2024 using a spectrophotometer for checking haemoglobin levels. Iron and protein intake were traced by a 24-hour food records questionnaire over 2 days. Results: There are 118 samples with 25.42% male and 74.58% female. Normal mean haemoglobin levels were detected in this study (12.59±0.82). The correlation tests, with the t-test for iron and protein intake, are not significant, with p-values of 0.246 and 0.254, respectively. Also, total protein and iron intake from this study, with an Anova F-test, is not significant, with a p-value of 0.408. The amount of consumption of iron and protein intake is not significant in the hemoglobin levels of Faculty of Medicine Students of the University.
References
Billett, H. H. (1990). Hemoglobin and Hematocrit. In H. K. Walker (Eds.) et. al., Clinical Methods: The History, Physical, and Laboratory Examinations. (3rd ed.). Butterworths.
Duryea, E. L., & Schell, R. C. (2024). Anemia. In Queenan’s Management of High-Risk Pregnancy: An Evidence-Based Approach, 99-104. https://doi.org/10.1002/9781119636540.ch12
Wang, T. F. Approach to Anemia. https://ccme.osu.edu/WebCastsFiles/781Approach%20to%20Anemia%20Final%20-%204.pdf
O’Neil, J. (2017). Diagnosing and Classifying Anemia in Adult Primary CAre.
Safiri, S., Kolahi, A. A., Noori, M., Nejadghaderi, S. A., Karamzad, N., Bragazzi, N.L., et al. (2021). Burden of anemia and its underlying causes in 204 countries and territories, 1990–2019: results from the Global Burden of Disease Study 2019. J Hematol Oncol, 14(1), 1–16. https://doi.org/10.1186/s13045-021 01202-2
Thompson, J. L., Manore, M. M., Vaughan, L. A., Gottschall-Pass, K., & MacLellan, D. L. (2011). The science of nutrition (Canadian Edition). Pearson Education, Inc.
World Health Organization. (2019). Prevalence of anaemia in women of reproductive age (aged 15-49) (%). https://www.who.int/data/gho/data/indicators/indicator-details/GHO/prevalence-of-anaemia-in-women-of-reproductive-age-(-)
Sari, P., Herawati, D. M. D., Dhamayanti, M., & Hilmanto, D. (2022). Anemia among Adolescent Girls in West Java, Indonesia: Related Factors and Consequences on the Quality of Life. Nutrients, 14(18), 1–13. https://doi.org/10.3390/nu14183777
Samson, K. L. I., Fischer, J. A. J., & Roche, M. L. (2022). Iron Status, Anemia, and Iron Interventions and Their Associations with Cognitive and Academic Performance in Adolescents: A Systematic Review. Nutrients, 14(1), 1–35. https://doi.org/10.3390/nu14010224
Timmer, T. C., de Groot, R., Rijnhart, J. J. M., Lakerveld, J., Brug, J., Perenboom, C. W. M., Baart, M. A., Prinsze, F. J., Zalpuri, S., van der Schoot, E. C., de Kort, W. L. A. M., & van den Hurk, K. (2020). Dietary intake of heme iron is associated with ferritin and hemoglobin levels in Dutch blood donors: results from Donor InSight. Haematologica, 105(10), 2400–2406. https://doi.org/10.3324/haematol.2019.229450
Li N, Zhao G, Wu W, Zhang M, Liu W, Chen Q, et al. (2020). The Efficacy and Safety of Vitamin C for Iron Supplementation in Adult Patients With Iron Deficiency Anemia: A Randomized Clinical Trial. JAMA Netw Open, 3(11), 1–9. doi:10.1001/jamanetworkopen.2020.23644
Jumiyati, J., Witradharma, T. W., Krisnasary, A., & Yulianti, R. (2023). Anemia among Adolescent Girls: Its Association with Protein and Iron Intake. Media Gizi Indonesia, 18(1SP), 14–20. https://doi.org/10.20473/mgi.v18i1SP.14-20
Yanti, S., Sari, Y. A. P., & Meilina , A. (2024). Diet, Protein, Iron and Vitamin C Intake on Anemia Status of Adolescent Girls. Journal of Applied Nursing and Health, 6(1), 177–183. https://doi.org/10.55018/janh.v6i1.192
Erningtyas, C., Faizah, Z., & Amalia, R. B. (2022). Overview Of Protein and Fe Intake with The Event of Anemia in Adolescent: Systematic Review. PLACENTUM Jurnal Ilmiah Kesehatan dan Aplikasinya, 10(3), 170 – 179 . https://doi.org/10.20961/placentum.v10i3.58355
Harahap, A.N., Purba, R., & Nainggolan, E.S. (2023). Literature Review: The Effectiveness of the Blood Supplement Tablet Program and Protein Intake in the Prevention of Anemia in Young Girls. Media Gizi Ilmiah Indonesia, 1(1), 33–42. https://doi.org/10.62358/mgii.v1i1.9
Pradanti, C. M., M, W., & K, H. P. (2015). Hubungan Asupan Zat Besi (Fe) dan Vitamin C dengan Kadar Hemoglobin pada Siswi Kelas VIII SMP Negeri 3 Brebes. Jurnal Gizi, 4(1), 24 – 29. https://doi.org/10.26714/jg.4.1.2015.%25p
Hardianti, A., Paratmanitya, Y., Nurunniyah, S., Jannah, M., & Hamdani, R. (2020). Correlation between Knowledge about Anemia, Iron, and Folate Consumption with Anemia Status among Premarital Women in Bantul Regency, Yogyakarta. Journal of nutritional science and vitaminology, 66(Supplement), 376–379. https://doi.org/10.3177/jnsv.66.S376
Sitorus, E. P. R., Handayani, S., Balyas, A. B., Widayati, R., Fatmaria, F., & Permatasari S. (2024). The Correlation between Protein, Iron, and Vitamin C Intake with Hemoglobin Levels in Pregnant Women. Mutiara Medika: Jurnal Kedokteran dan Kesehatan, 24(1), 19–24. https://doi.org/10.18196/mmjkk.v24i1.17311
Matayane, S. G., Bolang, A. S. L., & Kawengian, S. E. S. (2014). Hubungan antara Asupan Protein dan Zat Besi dengan Kadar Hemoglobin Mahasiswa Program Studi Pendidikan Dokter angkatan 2013 Fakultas Kedokteran Universitas Sam Ratulangi. eBiomedik, 2(3). https://doi.org/10.35790/ebm.v2i3.5742
Kristin, N., Jutomo, L., & Boeky, D. L. A. (2022). Hubungan Asupan Zat Gizi Besi Dengan Kadar Hemoglobin Remaja Putri. Sehat Rakyat: Jurnal Kesehatan Masyarakat, 1(3), 189–95. https://doi.org/10.54259/sehatrakyat.v1i3.1077
Indraswari, D. A. R., Padmiari, I. A. E., & Suarjana, I. M. (2024). Konsumsi Seng (Zn) dan Zat Besi (Fe) dan Kadar Hemogoblin Pada Siswi SMA Negeri 1 Gianyar. Jurnal Ilmu Gizi : Journal of Nutrition Science, 13(2), 86–93. https://doi.org/10.33992/jig.v13i2.2776
Putri, T. F., & Fauzia, F. R. (2022). Hubungan Konsumsi Sumber Zat Besi dengan Kejadian Anemia pada Remaja Putri SMP dan SMA di wilayah Bantul. Jurnal Ilmu Keperawatan dan Kebidanan, 13(2), 400–11. https://doi.org/10.26751/jikk.v13i2.1540
Indartanti, D., & Kartini, A. Hubungan Status Gizi dengan Kejadian Anemia pada Remaja Putri. Journal of Nutrition College, 3(2), 310–6. https://doi.org/10.14710/jnc.v3i2.5438
Lewa, A. F. (2016). Hubungan Asupan Protein, Zat Besi dan Vitamin C dengan Kejadian Anemia pada Remaja Putri di MAN 2 Model Palu. Jurnal Publikasi Kesehatan Masyarakat Indonesia, 3(1), 26 – 31. 10.20527/jpkmi.v3i1.2736
Septyasih, A. R. N., Widajanti, L., & Nugraheni, S. A. (2016). Hubungan Asupan Zat Besi, Asam Folat, Vitamin B12 dan Vitamin C dengan Kadar Hemoglobin Siswa di SMP Negeri 2 Tawangharjo Kabupaten Grobogan. Jurnal Kesehatan Masyarakat, 4(4), 521–8. https://doi.org/10.14710/jkm.v4i4.14282
Baha, M. H., Patimah, S., Sumiaty., Gobel, F. A., & Nurlinda, A. (2021). Hubungan Konsumsi Zat Besi, Protein, Vitamin C dengan Kejadian Anemia Remaja Putri Kabupaten Majene. Window of Public Health Journal, 2(4), 657–69. https://doi.org/10.33096/woph.v2i4.258
Taruna, W. G. M., Mahayani, I. A. M., S, A. M., & Shammakh, A. A. (2023) Hubungan Pemberian Tablet Fe Terhadap Peningkatan Kadar Hemoglobin Pada Remaja Wanita Risiko Anemia. COMSERVA : Jurnal Penelitian dan Pengabdian Masyarakat, 2(11), 2574–81. https://doi.org/10.59141/comserva.v2i11.674
Soedijanto, S. G. A, Kapantow, N. H., & Basuki, A. (2015). Hubungan Antara Asupan Zat Besi Dan Protein Dengan Kejadian Anemia Pada Siswi SMP Negeri 10 Manado. Pharmacon, 4(4). https://doi.org/10.35799/pha.4.2015.10239
Rehman, T., Agrawal, R., Ahamed, F., Das, S., Mitra, S., Kumar, D., Sethy, C., Kanungo, S., Bhattacharya, D., & Pati, S. (2025). Optimal dose and duration of iron supplementation for treating iron deficiency anaemia in children and adolescents: A systematic review and meta-analysis. PloS one, 20(2), 1 – 23. https://doi.org/10.1371/journal.pone.0319068.
DeLoughery, T. G. (2017). Iron Deficiency Anemia. The Medical clinics of North America, 101(2), 319–332. https://doi.org/10.1016/j.mcna.2016.09.004
FINCH, C. A. (1957, May). The role of iron in hemoglobin synthesis. In Conference of hemoglobin.
Nurjannah, T. A., Elba, F., Nirmala, S. A., Mandiri, A., & Wijaya, M. (2021). Relationship between Nutrition Intake and Hemoglobin Levels in Toddlers Aged 12-24 Months. Althea Medical Journal, 8(1), 13-17. . https://doi.org/10.15850/amj.v8n1.2115
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