Various Pharmacological Activities in the Development of Kombucha as A Functional Food Ingredient with Economic Potential: A Literature Review
Authors
Firman Rezaldi , Nia Agustina , Paramita Wisnuwardhani , Fahmi Alamil Huda , Erni SuminarDOI:
10.29303/jbt.v26i1.11417Published:
2026-01-22Issue:
Vol. 26 No. 1 (2026): Januari-MaretKeywords:
Economic potential, Fermentation, Functional food, Kombucha, Pharmacological activityArticles
Downloads
How to Cite
Downloads
Abstract
Kombucha is a fermented beverage produced by a symbiotic culture of bacteria and yeast (SCOBY) and has gained increasing attention as a functional food due to its bioactive compounds. This literature review aims to evaluate the pharmacological activities of kombucha and its potential development as a functional food with economic value. A systematic literature review was conducted using reputable international databases, including Scopus, Web of Science, PubMed, and ScienceDirect, covering publications from 2015 to 2025. The findings indicate that kombucha consistently exhibits antioxidant, antibacterial, anti-inflammatory, antidiabetic, anticancer, and cosmetic-related bioactivities. These effects are influenced by substrate type, fermentation conditions, and microbial composition, which determine the production of organic acids, polyphenols, flavonoids, and postbiotic metabolites. Beyond its health benefits, kombucha contributes significantly to economic development through product diversification, utilization of local resources and agro-industrial by-products, and entrepreneurial opportunities for small and medium enterprises. Nevertheless, challenges related to quality standardization, food safety, and health claim regulations remain critical issues. Overall, kombucha demonstrates strong potential as a functional food and an economically valuable fermented biotechnology product.
References
Agustiansyah, L. D., Fadillah, M. F., Somantri, U. W., Sasmita, H., Jubaedah, D., & Trisnawati, D. (2022). Produk Bioteknologi Farmasi Sebagai Antifungi Candida albicans Dalam Bentuk Formulasi Sediaan Sampo Gel Kombucha Bunga Telang (Clitoria ternatea L). Jurnal Ilmiah Farmasi Attamru (JIFA), 3(2), 24-35.
Al-Dulaimi, F. K., Abd-Alwahab, W. I., & Hasan, A. S. (2018). Bioactivity study of kombucha black tea and kombucha with skim milk on some of physiological and biochemical parameters in male albino rats. Int. J. Pharm. Res, 10, 301.
Alkan, G., Konar Erol, N. M., Yıkmış, S., Er, H., Öğüt, S., & Yinanç, A. (2025). Kombucha’s functional features and fermentation dynamics: a bibliometric assessment in sustainable food production. Frontiers in Sustainable Food Systems, 9, 1593348.
ALVES, R. O., de OLIVEIRA, R. L., dos ANJOS, D. C. P., PORTO, C. S., & PORTO, T. S. (2024). Uma Trends in kombucha research: a bibliometric and technological prospection analysis. Food Science and Technology, 44.
Anantachoke, N., Duangrat, R., Sutthiphatkul, T., Ochaikul, D., & Mangmool, S. (2023). Kombucha beverages produced from fruits, vegetables, and plants: A review on their pharmacological activities and health benefits. Foods, 12(9), 1818.
Anggraini, D. A., Rezaldi, F., Sofianti, A., Mathar, I., & Kolo, Y. (2023). Pharmaceutical Biotechnology Products In The Form Of Hand Washing Soap Kombucha Bunga Telang (Clitoria Ternatea L) As Antibacterial For Salmonella Thypi And Listeria Monocytogenes. Jurnal Biologi Tropis, 23(2), 381-389.
Antolak, H., Piechota, D., & Kucharska, A. (2021). Kombucha tea—A double power of bioactive compounds from tea and symbiotic culture of bacteria and yeasts (SCOBY). Antioxidants, 10(10), 1541.
Aung, T., & Eun, J. B. (2021). Production and characterization of a novel beverage from laver (Porphyra dentata) through fermentation with kombucha consortium. Food chemistry, 350, 129274.
Ayed, L., & Hamdi, M. (2015). Manufacture of a beverage from cactus pear juice using “tea fungus” fermentation. Annals of Microbiology, 65(4), 2293-2299.
Ayed, L., Ben Abid, S., & Hamdi, M. (2017). Development of a beverage from red grape juice fermented with the Kombucha consortium. Annals of microbiology, 67(1), 111-121.
Banerjee, D., Hassarajani, S. A., Maity, B., Narayan, G., Bandyopadhyay, S. K., & Chattopadhyay, S. (2010). Comparative healing property of kombucha tea and black tea against indomethacin-induced gastric ulceration in mice: possible mechanism of action. Food & function, 1(3), 284-293.
Barros, V. C., Botelho, V. A., & Chisté, R. C. (2024). Alternative substrates for the development of fermented beverages analogous to kombucha: an integrative review. Foods, 13(11), 1768.
Četojević-Simin, D. D., Velićanski, A. S., Cvetković, D. D., Markov, S. L., Mrđanović, J. Ž., Bogdanović, V. V., & Šolajić, S. V. (2012). Bioactivity of lemon balm kombucha. Food and Bioprocess Technology, 5(5), 1756-1765.
Chou, Y. C., Lin, H. W., Wang, C. Y., Hsieh, C. C., Santoso, S. P., Lin, S. P., & Cheng, K. C. (2024). Enhancing antioxidant benefits of Kombucha through optimized glucuronic acid by selected symbiotic fermentation culture. Antioxidants, 13(11), 1323.
das Chagas, E. G. L., Zamarian, F. C., de Souza, H. F., Kamimura, E. S., Boffo, E. F., & Ambrozin, A. R. P. (2024). Extraction of Polyphenols and Antioxidant Compounds from SCOBY, as a by-product of Kombucha, Using Different Types of Extraction. Discover Food, 4(1), 54.
de Oliveira, P. V., da Silva Júnior, A. H., de Oliveira, C. R. S., Assumpção, C. F., & Ogeda, C. H. (2023). Kombucha benefits, risks and regulatory frameworks: A review. Food Chemistry Advances, 2, 100288.
Düşgün, C. (2024). Investigation of the Antioxidant Potential of Kombucha Prepared Using Salvia officinalis L. Turkish Journal of Agriculture-Food Science and Technology, 12(s2), 2292-2297.
Fachani, S., Kustyarini, F., Herlina, E., Widianingsih, R., Tamaam, R. M. N., Arvilando, M., ... & Perkasa, B. T. (2025). Potential Of Purple Variety Of Telang Flower (Clitoria ternatea L) Kombucha As An Antibacterial For Escherichia coli Isolated From Three Samples Of Livestock Dung Around Sman 5 Cilegon. TASTECH (Journal of Tropical Animal Science and Feed Technology), 1(2).
Fadhillah, M., Rezaldi, F., Yenny, R. F., Maritha, V., Ayuwardani, N., & Suminar, E. (2024). Antibakteri Keracunan Bahan Pangan Pada Formulasi Sediaan Sabun Mandi Kombucha Bunga Telang Sebagai Produk Bioteknologi Farmasi Dari 3 Lokasi Budidaya. Jurnal Ilmiah Biosaintropis (Bioscience-Tropic), 10(1), 44-56.
Fatonah, N. S., Pertiwi, F. D., Rezaldi, F., Abdilah, N. A., & Fadillah, M. F. (2022). Uji Aktivitas Antibakteri Escherichia Coli Pada Formulasi Sediaan Sabun Cair Mandi Probiotik Dengan Metode Bioteknologi Fermentasi Kombucha Bunga Telang (Clitoria ternatea L). AGRIBIOS, 20(1), 27-37.
Febriana, L., Putra, R. P., Rezaldi, F., Erikania, S., Nurmaulawati, R., & Priyoto, P. (2023). Uji Daya Hambat Propinobacterium acnes pada Produk Bioteknologi Farmasi Sediaan Sabun Wajah Kombucha Bunga Telang (Clitoria ternatea L). Jurnal Farmagazine, 10(1), 70-78.
Guruvayoorappan, C., & Kuttan, G. (2008). (+)-Catechin inhibits tumour angiogenesis and regulates the production of nitric oxide and TNF-α in LPS-stimulated macrophages. Innate immunity, 14(3), 160-174.
Husein, A. S., Rezaldi, F., Pamungkas, B. T., Suminar, E., Maritha, V., & Gumilar, R. (2025). FORMULASI SEDIAAN SABUN WAJAH BERBAHAN AKTIF EKSTRAK SARANG BURUNG WALLET DAN SCOOBY KOMBUCHA SEBAGAI ANTIPENUAAN BERDASARKAN DAYA HAMBAT ENZIM TIROSINASE. Jurnal Ilmiah Farmasi Attamru (JIFA), 6(1), 26-37.
Kanno, S. I., Shouji, A., Tomizawa, A., Hiura, T., Osanai, Y., Ujibe, M., ... & Ishikawa, M. (2006). Inhibitory effect of naringin on lipopolysaccharide (LPS)-induced endotoxin shock in mice and nitric oxide production in RAW 264.7 macrophages. Life Sciences, 78(7), 673-681.
Kitwetcharoen, H., Phung, L. T., Klanrit, P., Thanonkeo, S., Tippayawat, P., Yamada, M., & Thanonkeo, P. (2023). Kombucha healthy drink—recent advances in production, chemical composition and health benefits. Fermentation, 9(1), 48.
Ma’ruf, A., Safitri, E., Pertiwi, F. D., Ningtias, R. Y., Trisnawati, D., Rezaldi, F., Kusumiyati., K., & Andayaningsih, P. (2022). Produk Bioteknologi Farmasi Berupa Sabun Mandi Kombucha Bunga Telang (Clitoria ternatea L) Sebagai Antifungi Candida albicans. Jurnal Pertanian, 13(2), 78-84.
Maghfirah, D., Pulungan, A. F., Ridwanto, R., & Yuniarti, R. (2025). Perbandingan Kandungan Fenolik dan Aktivitas Antioksidan pada Varian Seduhan Teh dan Varian Teh Kombucha Secara Spektrofotometri Visible. Journal of Pharmaceutical and Sciences, 1384-1397.
Mfopa, A. N., Kemzeu, R., Fokom, R., Yamthe, L. R. T., Dize, D., & Boyom, F. F. (2024). Phenolic compounds, antioxidant and antileishmanial activities of kombucha as affected by fermentation time. Heliyon, 10(22).
Nurmaulawati, R., Rezaldi, F., Susilowati, A. A., Waskita, K. N., Puspita, S., & Rosalina, V. (2022). Antimikroba Pada Produk Bioteknologi Farmasi Berupa Sediaan Obat Kumur Kombucha Bunga Telang (Clitoria ternatea L). Jurnal Ilmiah Farmasi Attamru (JIFA), 3(2), 1-16.
Nworu, C. S., & Akah, P. A. (2015). Anti-inflammatory medicinal plants and the molecular mechanisms underlying their activities. African Journal of Traditional, Complementary and Alternative Medicines, 12, 52-61.
Oguntibeju, O. O. (2018). Medicinal plants with anti-inflammatory activities from selected countries and regions of Africa. Journal of inflammation research, 307-317.
Oktavia, S., Novi, C., Handayani, E. E., Abdilah, N. A., Setiawan, U., & Rezaldi, F. (2021). Pelatihan Pembuatan Immunomodulatory Drink Kombucha untuk Meningkatkan Perekonomian Masa New Normal pada Masyarakat Desa Majau dan Kadudampit Kecamatan Saketi Kabupaten Pandeglang, Banten. Jurnal Pengabdian Pada Masyarakat, 6(3), 716-724.
Onsun, B., Toprak, K., & Sanlier, N. (2025). Kombucha Tea: A Functional Beverage and All its Aspects. Current Nutrition Reports, 14(1), 69.
Pamungkas, B. T., Safitri, A., Rezaldi, F., Andry, M., Agustiansyah, L. D., Fadillah, M. F., ... & Hariadi, H. (2022). Antifungal Trycophyton Rubrum And Trycophyton Mentagrophytes In Liquid Bath Soap Fermented Probiotic Kombucha Flower Telang (Clitoria Ternatea L) As A Pharmaceutical Biotechnology Product. BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan, 10(2), 179-196.
Permatasari, H. K., Nurkolis, F., Gunawan, W. B., Yusuf, V. M., Yusuf, M., Kusuma, R. J., ... & Tsopmo, A. (2022). Modulation of gut microbiota and markers of metabolic syndrome in mice on cholesterol and fat enriched diet by butterfly pea flower kombucha. Current Research in Food Science, 5, 1251-1265.
Pure, A. E., & Pure, M. E. (2016). Antioxidant, antibacterial and color analysis of garlic fermented in kombucha and red grape vinegar. Applied Food Biotechnology, 3(4), 246-252.
Putra, R. P., Rezaldi, F., Fadillah, M. F., Priyoto, P., & Sumiardi, A. (2023). Antibakteri Penyebab Bau Ketiak (Staphylococcus hominis) Dari Sediaan Sabun Mandi Kombucha Bunga Telang (Clitoria Ternatea L) Sebagai Produk Bioteknologi Farmasi. Agrinula: Jurnal Agroteknologi dan Perkebunan, 6(1), 1-14.
Rasouli, L., Aryaeian, N., Gorjian, M., Nourbakhsh, M., & Amiri, F. (2021). Evaluation of cytotoxicity and anticancer activity of kombucha and doxorubicin combination therapy on colorectal cancer cell line HCT-116. Journal of education and health promotion, 10(1).
Rezaldi, F., Qonit, M. A. H., Nuraini, A., Kusumiyati, K., & Mubarok, S. (2019). Pemanfaatan fenomena pembentukan buah partenokarpi dalam perspektif pertanian di Indonesia. Kultivasi, 18(2), 859-868.
Rezaldi, F., Ningtyas, R. Y., Anggraeni, S. D., Ma’ruf, A., Fatonah, N. S., Pertiwi, F. D., ... & Subekhi, A. I. (2021). Pengaruh metode bioteknologi fermentasi kombucha bunga telang (Clitoria ternatea L) sebagai antibakteri gram positif dan negatif. Jurnal Biotek, 9(2), 169-185.
Rezaldi, F., Rachmat, O., Fadillah, M. F., Setyaji, D. Y., & Saddam, A. (2022). Bioteknologi Kombucha Bunga Telang (Clitoria ternatea L) Sebagai Antibakteri Salmonella thypi dan Vibrio parahaemolyticus Berdasarkan Konsentrasi Gula Aren. Jurnal Gizi Kerja dan Produktivitas, 3(1), 13-22.
Rezaldi, F., Agustiansyah, L. D., Safitri, E., Oktavia, S., & Novi, C. (2022). Antifungi Candida albicans, Aspergilus fumigatus, dan Pitosporum ovale Dari Sediaan Sampo Probiotik Kombucha Bunga Telang (Clitoria ternatea L) Sebagai Produk Bioteknologi Farmasi. Pharmaqueous: Jurnal Ilmiah Kefarmasian, 4(1), 45-52.
Rezaldi, F., Fadillah, M. F., Mu’jijah, M. J., Abdilah, N. A., & Meliyawati, M. (2022). Potensi kombucha bunga telang sebagai himbauan kepada wisatawan pantai carita dalam meningkatkan imunitas. SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan, 6(2), 867-871.
Rezaldi, F., Mathar, I., Nurmaulawati, R., Galaresa, A. V., & Priyoto, P. (2023). Pemanfaatan Kombucha Bunga Telang (Clitoria ternatea L) Sebagai Upaya Dalam Mencegah Stunting Dan Meningkatkan Imunitas Di Desa Ngaglik Magetan Parang. Jurnal Abdimas Bina Bangsa, 4(1), 344-357.
Rezaldi, F., Anggraeni, S. D., Ma'ruf, A., Andry, M., Faisal, H., Winata, H. S., ... & Nasution, M. A. (2023). Antibakteri pada formulasi sediaan sabun mandi kombucha bunga telang (Clitoria ternatea L) sebagai produk bioteknologi farmasi. Jurnal Biotek, 11(1), 73-86.
Rezaldi, F., Firmansyah, F., Maharani, M., Hayani, R. A., Margarisa, D., Purchia, I. D., ... & Ramadhan, R. A. (2023). Pemberian Edukasi Mengenai Bioteknologi Kombucha Bunga Telang Sebagai Minuman Probiotik Peningkat Sistem Imun, Bahan Aktif Obat dan Kosmetik, Bahan Baku Pupuk Cair Organik, dan Peningkat Ekonomi Kepada Siswa SMAN 05 Cilegon Yang Terlibat Dalam Karya Ilmia. Jurnal Pengabdian Magister Pendidikan IPA, 6(3), 749-760.
Rezaldi, F., Rusmana, R., Susiyanti, S., Maharani, M., Hayani, R. A., Firmansyah, F., & Mubarok, S. (2023). Bioteknologi Kombucha Bunga Telang Sebagai Formulasi dan Sediaan Spray dalam Menghambat Pertumbuhan Fungi Fusarium solani Penyebab Penyakit Tanaman Komoditas Hortikultura. Jurnal Bios Logos, 13(3), 254-265.
Rezaldi, F., Utami, A. W., Wijayanti, F. E. R., Purbanova, R., Wati, D. R., Suminar, E., ... & Yenny, R. F. (2024). Aktivitas Antioksidan Pada Sediaan Kombucha Bunga Telang Yang Diracik Dari Formulasi Gula Aren Dan Madu Sr12 Sebagai Produk Bioteknologi Pangan Dan Farmasi. Agribios, 22(2), 165-175.
Rezaldi, F., Millah, Z., Susiyanti, S., Gumilar, R., & Yenny, R. F. (2024). Peran Biotek Gen Tanaman Pada Bidang Pangan dan Farmasi Sebagai Bahan Sediaan Pangan Fungsional, Bahan Aktif Obat dan Kosmetik Natural. Jurnal Agroteknologi Merdeka Pasuruan, 8(1), 01-09.
Rezaldi, F., Maritha, V., Yenny, R. F., Fadillah, M. F., Sugiono, S., Saifullah, I., ... & Kolo, Y. (2024). Kajian Pustaka: Isu Isu Terkini Mengenai Produk Bioteknologi Yang Mengarah Pada Rekayasa Genetika (Gmo/Genetically Modified Organism) Serta Tidak Terbukti Secara Ilmiah Merugikan Dari Sudut Pandang (Hukum, Peternakan, Pertanian, Dan Farmasi). Jurnal Ilmiah Farmasi Attamru (JIFA), 5(2), 46-84.
Rezaldi, F., Maritha, V., Yenny, R. F., Saifullah, I., Sugiono, S., Rohmatulloh, R., ... & Kusumiyati, K. (2024). Formulasi Sediaan Spray Alami Pada Kombucha Bunga Telang Sebagai Produk Bioteknologi Farmasi Dan Antifungi Pada Tanaman Komoditas Hortikultura Jenis Kentang (Solanum tuberosum L). Agribios, 22(1), 1-10.
Rezaldi, F., Nurmayulis, N., Rusmana, R., Yenny, R. F., & Rustini, R. (2024). Produk Bioteknologi Farmasi Berupa Sediaan Sabun Cuci Tangan Kombucha Bunga Telang Sebagai Antibakteri Staphylococcus aureus dari Isolat Usus Sapi. Jurnal Kesehatan Tujuh Belas (Jurkes TB), 5(2).
Rezaldi, F., Safitri, A., Agustiansyah, L. D., Andry, M., & Fadillah, M. F. (2024, January). Uji Aktivitas Antibakteri Pseudomonas aeruginosa pada Formulasi Sediaan Sabun Cuci Tangan Probiotik dengan Metode Bioteknologi Fermentasi Kombucha Bunga Telang (Clitoria ternatea L.). In Gunung Djati Conference Series (Vol. 38, pp. 33-47).
Rezaldi, F., Kolo, Y., Yenny, R. F., Maritha, V., Ayuwardani, N., Cahyono, A. T., ... & Purbanova, R. (2024). FORMULASI SEDIAAN ODOL KOMBUCHA BUNGA TELANG SEBAGAI PRODUK BIOTEKNOLOGI FARMASI DAN ANTIMIKROBA (Staphylococcus aureus, Streptococcus mutan, Candida albicans). Telang flower kombucha has been widely studied as a probiotic drink that can boost the immune s. PHARMACIA, 2(2), 1-14.
Rezaldi, F., Haryani, T. S., Utami, A. W., Nabilla, J., Hariningsih, Y., Eman, E., ... & Setiawan, U. (2025). Uji Antiketombe (Tiga Fungi Patogen Rambut) Pada Produk Bioteknologi Farmasi Berupa Formulasi dan Sediaan Sampo Gel Kombucha Bunga Telang (Clitoria ternatea L). Jurnal Ilmiah Biosaintropis (Bioscience-Tropic), 10(2), 96-107.
Rezaldi, F., & Ngete, A. F. (2025). Formulasi Sediaan Spray Alami dari Limbah Kombucha Bunga Telang sebagai Produk Bioteknologi Pertanian dan Farmasi dalam Menghambat Pertumbuhan Jamur Patogen pada Jambu Air (Syzygium aqueum). Jurnal Agroteknologi, 4(01), 11-21.
Salafzoon, S., Mahmoodzadeh Hosseini, H., & Halabian, R. (2018). Evaluation of the antioxidant impact of ginger-based kombucha on the murine breast cancer model. Journal of Complementary and Integrative Medicine, 15(1), 20170071.
Sanwal, N., Gupta, A., Bareen, M. A., Sharma, N., & Sahu, J. K. (2023). Kombucha fermentation: Recent trends in process dynamics, functional bioactivities, toxicity management, and potential applications. Food chemistry advances, 3, 100421.
Sofianti, A., Rezaldi, F., Mathar, I., Sumiardi, A., & Subagiyo, A. (2023). Produk Bioteknologi Farmasi Dengan Aktivitas Farmakologi Secara In Vitro Sebagai Antibakteri Staphylococcus aureus Berupa Formulasi Dan Sediaan Obat Kumur Kombucha Bunga Telang (Clitoria ternatea L). Jurnal Kesehatan dan Kedokteran, 2(1), 76-99.
Subagiyo, A., Rezaldi, F., Ma'ruf, A., Pertiwi, F. D., & Safitri, A. (2022). Antibakteri Vibrio parahaemolyticus dan Klebsiella pneumoniae pada Sediaan Sabun Mandi Probiotik Fermentasi Kombucha Bunga Telang (Clitoria ternatea L) Sebagai Produk Bioteknologi Farmasi. Journal oF Biotechnology and Conservation in WALLACEA, 2(2), 89-98.
Su, J., Tan, Q., Tang, Q., Tong, Z., & Yang, M. (2023). Research progress on alternative kombucha substrate transformation and the resulting active components. Frontiers in Microbiology, 14, 1254014.
Tandhanskul, A., Krungkaew, S., Li, L., Kham, S. A., & Yonekura, L. (2025). Kombucha as a Sustainable Source of Metabiotics: Potential, Applications, and Future Perspectives. Beverages, 11(6), 173.
Tu, C., Tang, S., Azi, F., Hu, W., & Dong, M. (2019). Use of kombucha consortium to transform soy whey into a novel functional beverage. Journal of Functional Foods, 52, 81-89.
Uțoiu, E., Matei, F., Toma, A., Diguță, C. F., Ștefan, L. M., Mănoiu, S., ... & Oancea, F. (2018). Bee collected pollen with enhanced health benefits, produced by fermentation with a Kombucha Consortium. Nutrients, 10(10), 1365.
Vázquez-Cabral, B. D., Larrosa-Pérez, M., Gallegos-Infante, J. A., Moreno-Jiménez, M. R., González-Laredo, R. F., Rutiaga-Quiñones, J. G., ... & Rocha-Guzmán, N. E. (2017). Oak kombucha protects against oxidative stress and inflammatory processes. Chemico-Biological Interactions, 272, 1-9.
Vianna, N. D. M., Albagli, G., Pereira, A. D. S., & Amaral, P. F. (2025). From Tea Fermentation to New Technologies: Multisectoral Applications of Kombucha SCOBY Through the Lens of Methodi Ordinatio. Fermentation, 11(10), 589.
Vitas, J. S., Cvetanović, A. D., Mašković, P. Z., Švarc-Gajić, J. V., & Malbaša, R. V. (2018). Chemical composition and biological activity of novel types of kombucha beverages with yarrow. Journal of functional foods, 44, 95-102.
Watawana, M. I., Jayawardena, N., Gunawardhana, C. B., & Waisundara, V. Y. (2016). Enhancement of the antioxidant and starch hydrolase inhibitory activities of king coconut water (Cocos nucifera var. aurantiaca) by fermentation with kombucha ‘tea fungus’. International Journal of Food Science and Technology, 51(2), 490-498.
Zhang, S., Tang, Y., & Chen, J. (2022). Changes in functional components and biological activity of Lycium barbarum after fermentation with Kombucha SCOBY. Journal of Food Processing and Preservation, 46(8), e16758.
Ziemlewska, A., Nizioł-Łukaszewska, Z., Bujak, T., Zagórska-Dziok, M., Wójciak, M., & Sowa, I. (2021). Effect of fermentation time on the content of bioactive compounds with cosmetic and dermatological properties in Kombucha Yerba Mate extracts. Scientific Reports, 11(1), 18792.
Ziska, R., & Agustina, A. (2019, October). Cytotoxic activity assay of n-hexane extract of Solanum nigrum L. fruits fermented by kombucha against MCF-7 breast cancer cell line. In Journal of Physics: Conference Series (Vol. 1338, No. 1, p. 012027). IOP Publishing.
Zubaidah, E., Dewantari, F. J., Novitasari, F. R., Srianta, I., & Blanc, P. J. (2018). Potential of snake fruit (Salacca zalacca (Gaerth.) Voss) for the development of a beverage through fermentation with the Kombucha consortium. Biocatalysis and Agricultural Biotechnology, 13, 198-203.
Zubaidah, E., Afgani, C. A., Kalsum, U., Srianta, I., & Blanc, P. J. (2019). Comparison of in vivo antidiabetes activity of snake fruit Kombucha, black tea Kombucha and metformin. Biocatalysis and Agricultural Biotechnology, 17, 465-469.
Zubaidah, E., Iastika, A. R., Widyaningsih, T. D., & Febrianto, K. (2021, April). Immunomodulatory activity of black tea kombucha (Camellia sinensis) and Arabica coffee leaves tea kombucha (coffee Arabica) for Salmonella typhi-infected mice. In IOP Conference Series: Earth and Environmental Science (Vol. 733, No. 1, p. 012128). IOP Publishing.
Zubaidah, E., Hasfiani, Y., & Sujuti, H. (2025). Physicochemical properties and anti-cancer activity of Javanese turmeric Kombucha (Curcuma xanthorrhiza) against t47d cell line. Trends in Sciences, 22(9), 10417-10417
License
Copyright (c) 2026 Firrman Rezaldi, Nia Agustina, Paramita Wisnuwardhani, Fahmi Alamil Huda, Erni Suminar

This work is licensed under a Creative Commons Attribution 4.0 International License.

Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.
The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.
Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.
























