Vol. 26 No. 3 (2026): in Progress
Open Access
Peer Reviewed

Formulation and Physical Evaluation of Peel Off Gel Mask Containing Nutmeg Seed (Myristica fragrans Houtt.) Extract with Different Polyvinyl Alcohol (PVA) Concentrations

Authors

Adelia Marsaoly , Neneng Siti Silfi Ambarwati , Dwi Atmanto

DOI:

10.29303/jbt.v26i3.12861

Published:

2026-07-29

Downloads

Abstract

Polyvinyl alcohol (PVA) serves as a film-forming substance that significantly influences the physical properties of peel-off gel masks. Changes in the concentration of PVA can impact the formulation's quality, affecting factors like viscosity, ease of spreading, stickiness, and drying duration. The ethanolic extract of nutmeg seeds (Myristica fragrans Houtt.) is rich in flavonoids that possess antioxidant properties, making it an advantageous active component for the formulations of peel-off gel masks. This study aimed to formulate a peel-off gel mask containing nutmeg seed extract with different PVA concentrations (10%, 12%, and 14%) and to evaluate its physical characteristics. The extract was acquired through maceration with 96% ethanol, and its antioxidant ability was assessed by the DPPH method. The physical assessment involved examining organoleptic features, homogeneity, pH, viscosity, spreadability, adhesiveness, and drying duration. The results were evaluated using One-Way ANOVA or Welch ANOVA, along with Tukey's HSD or Games-Howell post hoc tests based on the data characteristics. The findings indicated that the nutmeg seed extract displayed exceptionally strong antioxidant abilities, with an IC₅₀ value of 9.648 ppm. An increase in PVA concentration led to higher viscosity, adhesiveness, and drying duration, while it decreased spreadability. All formulations fulfilled the standards for organoleptic features, homogeneity, pH, spreadability, adhesiveness, and drying time. Nonetheless, the formulation with 14% PVA had a viscosity slightly over the suggested standard range. From the overall initial physical assessment, the formulation with 12% PVA was regarded as the most well-balanced formulation. Nevertheless, this formulation exhibited a more turbid appearance than the formulation containing 10% PVA. Further studies, including physical stability and safety evaluations, are required to confirm its suitability as the optimal formulation.

Keywords:

Antioxidant activity Myristica fragrans Houtt. Nutmeg seed Peel-off gel mask Polyvinyl alcohol (PVA) Physical evaluation

References

Abdullah, S. S., Antasionasti, I., Rundengan, G., Indarwati, R. P., & Ratulangi, U. S. (2022). Aktivitas Antioksidan Ekstral Etanol Biji dan Daging Buah Pala ( Myristica fragrans ) Dengan Metode DPPH. 15(2), 2–7. https://doi.org/10.35799/cp.15.2.2022.44893

Ahmad, Z., & Damayanti. (2018). Penuaan Kulit : Patofisiologi dan Manifestasi Klinis. Berkala Ilmu Kesehatan Dan Kelamin, 30(3), 208–215. https://share.google/Q4pPq0nXMEa2J9zV9

Ajimahtinur, S., Ulfa, A. M., Ayu, G., & Saputri, R. (2024). Formulasi Dan Uji Evaluasi Antibakteri Masker Gel Peel-Off Ekstrak Bunga Telang (Clitoria ternatea L.) Dengan Variasi Gelling Agent PVA. Jurnal Ilmiah Wahana Pendidikan, 10, 635–646. https://doi.org/https://jurnal.peneliti.net/index.php/JIWP/article/view/11424

Amelia, A. R., Putri, V. S., Ningsih, R. V., & Isthiningtyas, V. (2025). Formulasi dan Evaluasi Fisik Sediaan Masker Gel Peel Off Ekstrak Etanol Rimpang Kunyit ( Curcuma Zedoaria ) Variasi Konsentrasi PVA. Jurnal Farmasindo Politeknik Indonusa Surakarta, 9, 428–437. https://farmasindo.poltekindonusa.ac.id/index.php/jurnal_farmasindo/article/view/294/206

Arifin, A., Ida, N., & Sureda. (2025). Formulasi dan Uji Stabilitas Fisik Masker Gel Peel Off Ekstrak Metanol Alga Merah ( Eucheuma cottonii ) Variasi Konsentrasi Polivinil Alkohol ( Film Forming ). Jurnal Farmasi (Journal of Pharmacy), 14(1), 28–38. https://doi.org/10.373013/awpryp22

Bakari, M. F., Abdulkadir, W. S., & Thomas, N. A. (2025). Formulasi Dan Evaluasi Fisik Emulgel Ekstrak Etanol Biji Pala ( Myristica Fragrans Houtt ). Jurnal Farmasi Teknologi Sediaan Dan Kosmetika, 2(2), 112–129. https://doi.org/10.70075/jftsk.v2i2.189

BPS. (2025). Statistik Tanaman Perkebunan Tahunan Indonesia 2024 (Vol. 1). Badan Pusat Statistik.

Darbre, P. D., & Harvey, P. W. (2014). Parabens can enable hallmarks and characteristics of cancer in human breast epithelial cells: A review of the literature with reference to new exposure data and regulatory status. Journal of Applied Toxicology, 34(9), 925–938. https://doi.org/10.1002/jat.3027

Fauziah, Zakaria, N., Adriani, A., Nazirah, & Kurniasih, K. I. (2023). Formulasi dan Uji Stabilitas Sabun Padat Transparan Ekstrak Biji Pala (Myristica Fragrans Houtt). Journal Of Pharmaceutical And Sciences, 6(3), 951–957. https://doi.org/10.36490/journal-jps.com.v6i3.172

Isromarina, R., Intan, N. R. P., & Sari, E. R. (2020). Aktivitas Antijamur Ekstrak Etanol Biji Pala (Myristica fragrans Houtt). Jurnal Ilmiah Bakti Farmasi, 1(1), 33–36. https://ejournal.stifibp.ac.id/index.php/jibf/article/view/59

Kartika, D., Suci, P. R., Ikhda, C., & Hamidah, N. (2021). Formulasi Dan Sediaan Masker Gel Peel Off Ekstrak Temu Putih (Curcuma zedoaria ) Sebagai Anti Jerawat. Artikel Pemakalah Paralel, 351–358. https://proceedings.ums.ac.id/snpbs/article/view/53

Kashuri, M. (2024). Kosmetik Berbahan Dasar Asli Indonesia. Mitra Cendekia Media.

Kelutur, F. J., Handayany, F., & Safitri, E. (2025). Leunca dan Rahasia Kecantukan Alami: Inovasi Masker Gel Peel Off Berbasis Herbal. Deepublish.

Kim, S., & Seock, Y.-K. (2009). Impacts of health and environmental consciousness on young female consumers' attitude towards and purchase of natural beauty products. International Journal of Consumer Studies, 33(6), 627–638. https://doi.org/10.1111/j.1470-6431.2009.00817.x

Maulida, V. S., Zahra, A. A., Aini, K. N., Rafifa, M., Sabrina, M., & Putra, H. E. (2025). Literature Review Pengaruh Polimer dan Bentuk Zat Aktif terhadap Sifat Karakteristik Sediaan Masker Gel Peel Off. Jurnal Integrasi Kesehatan Dan Sains (JIKS), 7(2), 107–119. https://doi.org/10.29313/jiks.v7i2.6591

Mulyani, A. D., Rahayu, M. P., Aini, N., & Purnamasari, D. (2023). Formulasi dan Evaluasi Mutu Fisik Sediaan Masker Gel Peel- Off Ekstrak Biji Pinang ( Areca Catechu L .) Sebagai Antioksidan. Indonesian Journal of Pharmaceutical Education, 3(3), 400–412. https://doi.org/10.37311/ijpe.v3i3.22033

Nurdjannah, N. (2007). Teknologi pengolahan pala. Bogor, Indonesia: Balai Besar Penelitian dan Pengembangan Pascapanen Pertanian.

Rahmaniar, R., Balfas, R. F., & Febriani, A. K. (2024). Formulasi dan Uji Mutu Sediaan Masker Gel Peel Off Dari Ekstrak Daun Kelor ( Moringa Oleifera L ). Jurnal Ilmiah Jophus : Journal of Pharmacy UMUS, 6(01), 9–18. https://doi.org/10.46772/jophus.v6i01.1620

Rahmawanty, D., Yulianti, N., & Fitriana, M. (2015). Formulasi dan evaluasi masker wajah peel-off mengandung kuersetin dengan variasi konsentrasi gelatin dan gliserin. Media Farmasi: Jurnal Ilmu Farmasi, 12(1), 17–32. 10.12928/mf.v12i1.3019

Rahmawati, R. A., Suhesti, I., & Purwanto, D. S. (2023). Formulasi dan Evaluasi Fisik Masker Gel Peel Off Ekstrak Daun Turi (Sesbania grandiflora (L.) Poir.). Jurnal Farmasindo Politeknik Indonusa Surakarta P-ISSN, 7(1), 18–24. https://doi.org/10.46808/farmasindo.v7i1.159

Ririn, & Ulfah, V. P. M. N. (2023). Journal of Pharmaceutical and Health Research Formulasi Sediaan Masker Peel Off dari Ekstrak Buah Alpukat ( Persea Americana Mill .) dengan Variasi Konsentrasi Polivinil Alkohol ( PVA ) Journal of Pharmaceutical and Health Research. Journal of Pharmaceutical and Health Research, 4(2), 303–311. https://doi.org/10.47065/jharma.v4i2.3605

Rizkyah, A., & Karimah, S. N. (2023). Literature Review: Penuaan Dini Pada Kulit: Gejala, Faktor Penyebab dan Pencegahan. Jurnal Gizi Dan Kesehatan (JGK), 3(2), 107–116. https://doi.org/10.36086/jgk.v3i2.2029

Sulastri, A., & Chaerunisaa, A. Y. (2016). Formulasi Masker Gel Peel Off Untuk Perawatan Kulit Wajah. https://doi.org/10.24198/jf.v14i3.10602

Sutriningsih, & Astuti, I. W. (2017). Uji antioksidan dan formulasi sediaan masker peel-off dari ekstrak biji alpukat (Persea americana Mill.) dengan perbedaan konsentrasi PVA (polivinil alkohol). Indonesia Natural Research Pharmaceutical Journal, 1(2), 67–75.

Tegar, M. (2023). Kefarmasian, Teknologi dan Formulasi Sediaan Semi Solid Dalam Bidang. CV. Mitra Edukasi Negeri.

Thaib, C. M., Purwandari, V., Simarmata, A. E. Y., Sihaloho, R., & Simarmata, F. S. (2022). Umi Bit Merah (Beta vulgaris) Sebagai Sediaan Kosmetik. Ahlimedia Press.

Zubaydah, W. O. S., & Fandinata, S. S. (2020). Formulasi sediaan masker gel peel-off dari ekstrak buah tomat (Solanum Lycopersicum L.) beserta uji aktivitas antioksidan. Journal Syifa Sciences and Clinical Research, 2(2), 73-82. https://doi.org/10.37311/jsscr.v2i2.6980

Author Biographies

Adelia Marsaoly, Universitas Negeri Jakarta

Author Origin : Indonesia

Neneng Siti Silfi Ambarwati, Universitas Negeri Jakarta

Author Origin : Indonesia

Dwi Atmanto, Universitas Negeri Jakarta

Author Origin : Indonesia

Downloads

Download data is not yet available.

How to Cite

Marsaoly, A., Ambarwati, N. S. S., & Atmanto, D. (2026). Formulation and Physical Evaluation of Peel Off Gel Mask Containing Nutmeg Seed (Myristica fragrans Houtt.) Extract with Different Polyvinyl Alcohol (PVA) Concentrations. Jurnal Biologi Tropis, 26(3), 941–954. https://doi.org/10.29303/jbt.v26i3.12861

Similar Articles

1 2 3 4 5 6 7 8 9 10 > >> 

You may also start an advanced similarity search for this article.