Vol. 21 No. 2 (2021): Mei - Agustus
Open Access
Peer Reviewed

Specialty Dihydrobenzoxanthone’s Artocarpus Purified By Vacuum Liquid Chromatography (VLC)

Authors

Aliefman Hakim

DOI:

10.29303/jbt.v21i2.2639

Published:

2021-06-02

Downloads

Abstract

One family of plants that are source of bioactive chemicals is the Moraceae.Artocarpus is the main genus of the Moraceae. Several species of the genus Artocarpus have been isolated their secondary metabolites. The main fractions obtained from the VLC are analyzed again by TLC. Fractions that have same spots (Rf) pooled. Purification process on main factions are done repeatedly by radial chromatography. Flavonoid is the most found from Artocarpus plant. Dihydrobenzoxanthone is one of flavonoid derivatives which is successfully isolated from Artocarpus. Dihydrobenzoxanthone is only formed from the flavone with ring B which isoxygenated with pattern of 2', 4' and 5'. Students can be learned dihydrobenzoxanthoneââ¬â¢s Artocarpus by laboratory activities.à

Keywords:

Artocarpus dihydrobenzoxanthone students

References

Achmad, S.A., Hakim, E. H.,. Juliawaty, L. D., Makmur., L., dan Suyatno (1996), New Prenylated Flavone from Artocarpus champeden, J. Nat Prod, 59, 878-879. https://doi.org/10.1021/np960330q

Achmad, S.A., Hakim, E. H.,. Juliawaty, L. D., Makmur., L., Kusuma, S. dan Syah, Y. M. (1995), Eksplorasi Kimia Tumbuhan Tropis Indonesia, Seminar Nasional Etnobotani II, Yogyakarta, 112-113.

Boonlaksiri, C., Oonanant, W., Kongsaeree, P., Kittakoop, P., Tanticharoen, M., & Thebtaranonth, Y. (2000). An antimalarial stilbene from Artocarpus integer. Phytochemistry, 54(4), 415-417. https://doi.org/10.1016/S0031-9422(00)00074-1

Darmawati, A. A. S. K., Bawa, I. G. A. G., & Suirta, I. W. (2015). Isolasi dan Identifikasi Senyawa Golongan Flavonoid pada Daun Nangka (Artocarpus heterophyllus Lmk) dan Aktivitas Antibakteri terhadap Bakteri Staphylococcus aureus. Jurnal Kimia (Journal of Chemistry).

Ferlinahayati 1999. Norartokarpetin dan flavonoid terisoprenilasi dari kulit batang Artocarpus scortechinii King [Tesis]. Institut Teknologi Bandung. Bandung

Hakim, A. (2010). Diversity of secondary metabolites from Genus Artocarpus (Moraceae). Nusantara Bioscience, 2(3). https://doi.org/10.13057/nusbiosci/n020307

Heyne, K., (1987), Tumbuhan Berguna Indonesia II, Terjemahan, Penerbit Badan Litbang Kehutanan, Jakarta, 645-646.

Jayasinghe ULB, Samarakoon TB, Kumarihamy BMM, Hara N, Fujimoto Y. (2008). Four new prenylated flavonoids and xanthones from the root bark of Artocarpus nobilis. Fitoterapia 79: 37-41. https://doi.org/10.1016/j.fitote.2007.07.014

Jayasinghe, L., Balasooriya, B.A.I.S., Padmini,W.C., Hara, N., FujimotoY. (2004), Geranyl chalcone derivatives with antifungal and radical scavenging properties from the leaves of Artocarpus nobilis, Phytochemistry, 65, 1287-1290. https://doi.org/10.1016/j.phytochem.2004.03.033

Jenis, J., Baiseitova, A., Yoon, S. H., Park, C., Kim, J. Y., Li, Z. P., ... & Park, K. H. (2019). Competitive ñ-glucosidase inhibitors, dihydrobenzoxanthones, from the barks of Artocarpus elasticus. Journal of enzyme inhibition and medicinal chemistry, 34(1), 1623-1632. https://doi.org/10.1080/14756366.2019.1660653

Khan, M.R., Omoloso, A.D., Kihara, M., (2003) Antibacterial activity of Artocarpus heterophyllus, Fitoterapia, 74, 501-505. https://doi.org/10.1016/S0367-326X(03)00120-5

Nomura, T., Hano, S., and Aida M. (1998), Heterocycles, 47(2), 1179-1205. https://www.infona.pl/resource/bwmeta1.element.elsevier-6717c273-ac61-3f94-8497-dc82cb7add9b

Okunlola, A., & Adewusi, S. A. (2019). Development of theophylline microbeads using pregelatinized breadfruit starch (artocarpus altilis) as a novel co-polymer for controlled release. Advanced pharmaceutical bulletin, 9(1), 93. https://dx.doi.org/10.15171%2Fapb.2019.012

Pratap, R., & Ram, V. J. (2014). Natural and synthetic chromenes, fused chromenes, and versatility of dihydrobenzo [h] chromenes in organic synthesis. Chemical reviews, 114(20), 10476-10526. https://doi.org/10.1021/cr500075s

Sultanbawa, M.U.S., Surendrakumar, Sivagnanasundram. 1989. Two pyranodihydrobenzoxanthones from Artocarpus nobilis. Phytochemistry 28(2): 599-605. https://doi.org/10.1016/0031-9422(89)80059-7

Syah YM, Achmad SA, Ghisalberti EL, Hakim EH, Makmur L, Mujahidin D. (2002). Artoindonesianins Qââ¬âT, four isoprenylated flavones from Artocarpus champeden Spreng. (Moraceae). Phytochem 61 949-953. https://doi.org/10.1016/S0031-9422(02)00366-7

Syah, Y.M., Juliawaty, L.D., Achmad, S.A,. Hakim, E.H., Ghisalberti, E.L, (2006) Cytotoxic prenylated flavones from Artocarpus champeden, Journal Natural Medicine, 60, 308-312. https://link.springer.com/article/10.1007/s11418-006-0012-z

Wang, Y., Deng, T., Lin, L., Pan, Y., & Zheng, X. (2006). Bioassayââ¬Âguided isolation of antiatherosclerotic phytochemicals from Artocarpus altilis. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 20(12), 1052-1055. https://doi.org/10.1002/ptr.1990

Widyawaruyanti, A., Subehan, Kalauni, S.K., Awale, S., Nindatu, M., Zaini, N.C., Syafruddin, D., Asih, P.B.S.,Tezuka, Y., Kadota, S. (2007), New prenylated flavones from Artocarpus champeden, and their antimalarial activity in vitro, Journal Natural Medicine, 61, 410-413.

Zhao, J., & Dixon, R. A. (2010). The ââ¬Ëinsââ¬â¢ and ââ¬Ëoutsââ¬â¢ of flavonoid transport. Trends in plant science, 15(2), 72-80. https://doi.org/10.1016/j.tplants.2009.11.006

Harborne, J. B. (1989). Flavonoids. In Natural products of woody plants (pp. 533-570). Springer, Berlin, Heidelberg. https://link.springer.com/chapter/10.1007/978-3-642-74075-6_16

Author Biography

Aliefman Hakim, Pendidikan Kimia, Jurusan PMIPA, Universitas Mataram

Author Origin : Indonesia

Downloads

Download data is not yet available.

How to Cite

Hakim, A. (2021). Specialty Dihydrobenzoxanthone’s Artocarpus Purified By Vacuum Liquid Chromatography (VLC). Jurnal Biologi Tropis, 21(2), 412–415. https://doi.org/10.29303/jbt.v21i2.2639

Similar Articles

1 2 3 4 5 6 7 8 > >> 

You may also start an advanced similarity search for this article.