Identification of Bioactive Solutions of Corn Silk (Zea mays L.) Extract and Biological Activity Test By Bioinformatics
DOI:
10.29303/jbt.v23i1.5846Published:
2023-11-08Downloads
Abstract
Corn silk (Zea mays L.) is an agricultural by-product that is discarded as agricultural waste. Corn silk has secondary metabolite compounds that have the potential to become useful bioactive compounds. The purpose of this study is to recognize the bioactive potential of corn hair through compound identification and biological activity. The method used is preparation and extraction by maceration method followed by identification of compounds through LC-MS analysis method and Phytochemical test, bioinformatic PASS test based on data through PubChem, ChemSpider, and way2drug web. The results obtained from corn silk have a group of active compounds, including alkaloids, flavonoids, saponins, steroids and triterpenoids. Analysis of potential bioactivity received Acaciin compounds have high antioxidant bioactivity with a Pa value of 0.815, 2-arachidonoylglycerol has high potential antiinflammatory bioactivity with a Pa value of 0.736 and 1,2-di-O-methyl-4-[(2R)-2,4-dihydro butyramide shows moderate possible antibacterial activity with a Pa value of 0.643. This study concludes that corn silk has high bioactive potential as an antioxidant, anti-inflammatory and antibacterial.
Keywords:
Anti-bacterial, anti-inflammatory, anti-oxidant, corn silk.References
Amini, Fitrah. (2023). Optimasi Kombinasi Simplisia Buah Andaliman, Daun Sirsak, dan Kulit Manggis Sebagai Kandidat Obat Antikanker Payudara. Tesis. Program Studi Biokimia. Fakultas Matematika dan Ilmu Pengetahuan Alam. Institut Pertanian Bogor. Bogor. URL: https://repository.ipb.ac.id/handle/123456789/116009
Aukkanit, N., Kemngoen, T., & Ponharn, N. (2015). Utilization of corn silk in low fat meatballs and its characteristics. Procedia-Social and Behavioral Sciences, 197, pp.1403-1410. DOI: 10.1016/j.sbspro.2015.07.086
Arifin, H. A., Hashiguchi, T., Nagahama, K., Hashiguchi, M., Muguerza, M., Sakakibara, Y., Tanaka, H. (2021). Varietal Differences in Flavonoid and Antioxidant Activity in Japanese Soybean Accessions. Bioscience, Biotechnology, and Biochemistry. 85(4), 916-922. DOI: https://doi.org/10.1093/bbb/zbaa104
Cowan, S. W., Schirmer, T., Rummel, G., Steiert, M., Ghosh, R. A., Jansonius, J. N., & Rosenbusch, J. P. (1999). Crystal structure explain fuctional properties of two Escherichia Coliporin. Nature. 358, 722-33. DOI: 10.1038/358727a0
Fatimah, F., Martha, R. D., & Kusumawati, A. (2020). Deteksi dan Identifikasi Senyawa Flavonoid Ekstrak Etanol Kulit Batang Tanaman Majapahit (Crescentia cujete) dengan LCMS. CHEESA: Chemical Engineering Research Articles, 3(2), 88. DOI: https://doi.org/10.25273/cheesa.v3i2.7688.88-98
Filimonov, D. A., Lagunin, A. A., Gloriozova, T. A., Rudik, A. V., Druzhilovskii, D., & S., Pogodin, P. V., & Poroikov, V. V., (2014), Prediction of the biological activity spectra of organic compounds using the pass online web resource, Chemistry of Heterocyclic Compounds, 50(3), 444–457. DOI: https://doi.org/10.1007/s10593-014-1496-1
Fitriah, Aida. (2017). Analisis Interaksi Senyawa Flavonoid Sukun (Artocarpus altilis) Terhadap Reseptor Estrogen Alfa Secara In silico Sebagai Model Kandidat Antikanker Payudara. Skripsi. Jurusan Biologi. Fakultas Sains dan Teknologi. Universitas Islam Negeri Maulana Malik Ibrahim. Malang.
Himawan R. F. (2010). Kromatografi Cair Kinerja Tinggi (KCKT).
Jannah,A., Rachmawaty, D.U., & Maunatin. A. (2018). Uji Aktivitas Antibakteri Rambut Jagung Manis (Zea mays ssaccarata Strurt) terhadap Bakteri Staphylococcus aureus dan Escherichia coli. ALCHEMY: Journal of Chemistry, 5(4), 132-137. DOI: 10.18860/al.v5i4.4182
Hasanudin, K., Hashim, P.S., & Mustafa. (2012). Corn silk (Stigma maydis) in healthcare: A phytochemical and pharmacological review. Molecules 17, 9697–9715. DOI:10.3390/molecules17089697
Malikhana, A., Yuniastuti, A., R. Susanti., Nugrahaningsih, W. H. (2021). Studi In silico Potensi Senyawa Bioaktif Gembili (Dioscorea esculenta) Sebagai Ligan Pada Reseptor G6PD dan PTPN1. Prosiding Semnas Biologi ke-9. Fakultas Matematika dan Ilmu Pengetahuan Alam. Universitas Negeri Semarang.
Mangurana, W. O. I., Yusnaini., dan Sahidin. (2019). Analisis LC-MS/MS (Liquid Chromatography Mass Spectrometry) dan Metabolit Sekunder serta Potensi Antibakteri Ekstrak n-Heksana Spons Callyspongia aerizusa yang diambil pada kondisi tutupan Terumbu Karang yang berbeda di Perairan Teluk Staring. Jurnal Biologi Tropis, 19 (2) : 131 – 14.
Nessa, F., Ismail, Z., & Mohamed, N. (2012). Antimicrobial activities of extracts and flavonoid glycosides of corn silk (Zea mays L.) International journal of Biotechnology for Wellnes Industries,1, 115-121. DOI: 10.6000/1927-3037%2F2012.01.02.02
Oliver, S. P,. Gillespie, B. E., Lewis, M. J., Ivey, S. J., Almeida R. A., Luther, D. A., Jhonson, D. L., Lamar, K. C., Moorehead, H. D., & Dowlen, H. H. 2001. Efficacy of a new premilking teat disinfectan containing a phenolic combination for the prevention of mastitis. J. Dairy Sci. 84, 1545 – 1549. DOI: 10.3168/jds.s0022-0302(01)70189-0
Puspitarsari, Laode, Herman. (2018). Identifikasi Golongan Metabolit Sekunder dan Aktivitas Antioksidan Ekstrak Daun Brotowali (Tinospora tuberculata Beumee). ISTN. Jagakarsa Jakarta.
Rudi H. Paeru,S.P dan Trias Qurnia Dewi, S.P. (2012). Panduan Praktis Budidaya Jagung. Dok. Penebar Swadaya
Salsabila, S., Palupi, N.S. and Astawan, M., (2021). Potensi Rambut Jagung sebagai Minuman Fungsional. Jurnal Pangan, 30(2),pp.137-146. DOI: 10.33964/jp.v30i2.542
Solihah MA, Wan Rosli WI, Nurhanan AR. Phytochemicals screening and total phenolic content of Malaysian Zea mays hair extracts. International Food Research Journal, 2012, 19(4);1533–38. URL: http://eprints.usm.my/id/eprint/32493
Subroto, M, A., & H. Saputro. 2006. Gempur Penyakit dengan Sarang Semut. Jakarta: Penebar Swadaya.
Sudirman, S. 2011. Aktivitas Antioksidan dan Komponen Bioaktif Kangkung Air (Ipomoea aquatic forsk.). Fakultas Perikanan dan Ilmu Kelautan IPB.
Wedaswari IAI. (2018). Aktivitas Antioksidan Ekstrak Etanol dan Fraksi Daun Sirih Merah (Piper crocatum) Dengan Metode Rancimat dan Identifikasi dengan LC-MS.
Wijayanti, F., & Ramadhian, M, R. (2016). Efek rambut jagung (Zea mays) terhadap penurunan kadar kolesterol dalam darah. Majority, 5(3), 91-95.
Winarsi, H. (2007). Antioksidan Alami & Radikal Bebas. Yogyakarta: Kanisius
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