Formulation of Tembelekan Leaf Hand Sanitizer (Lantana camara L.) and Antibacterial Activity Test Against Escherichia coli and Staphylococcus aureus
DOI:
10.29303/jbt.v24i3.7595Published:
2024-09-03Downloads
Abstract
Disease-causing microorganisms stick to hands every day through physical contact with the environment. One of the easiest and most appropriate ways to clean them is to wash hands with soap and clean water. This study aims to determine the formulation of tembelekan leaf hand sanitizer (Lantana camara L.) and test its antibacterial activity against Escherichia coli and Staphylococcus aureus. Assessment of the arrangements acquired incorporates organoleptic tests with libertine tests, homogeneity, pH, spreadability, dependability, bothering to chip in skin, and antibacterial movement against Staphylococcus aureus and Escherichia coli by agar dispersion utilizing poke holes. The outcomes showed that the hand sanitizer readiness containing 10% tembelekan leaf remove was the best planning since it was liked by specialists, stable when put away at room temperature for a very long time, didn't cause bothering, and had solid antibacterial movement so that the tembelekan leaf gel planning utilized as a characteristic natural substance can be utilized to clean hands from microscopic organisms that is simple, reasonable and protected to use without utilizing water.
Keywords:
Escherichia coli, hand sanitizer gel, Staphylococcus aureus, Tembelekan leaves.References
Ardana, M., Aeyni, V., & Ibrahim, A. (2015). Formulasi dan optimasi basis gel HPMC (hidroxy propyl methyl cellulose) dengan berbagai variasi konsentrasi. Journal of Tropical Pharmacy and Chemistry, 3(2), 101-108. 10.25026/jtpc.v3i2.95
Departemen Kesehatan RI1. (1980). Materia Medika Indonesia. Jilid IV. Cetakan pertama. Jakarta : Direktorat Jendral Pengawasan Obat dan Makanan. Hal. 171.
Departemen Kesehatan RI1. (1989). Materia Medika Indonesia. Jilid V. Jakarta : Direktorat Jendral Pengawasan Obat dan Makanan. Hal. 549, 550, 552-553.
Departemen Kesehatan RI1. (1995). Materia Medika Indonesia. Jilid VI. Cetakan Keenam. Jakarta. Direktorat Jenderal Pengawasan Obat dan Makanan. Hal. 537.
Ditjen POM. (1995). Farmakope Indonesia. Edisi keempat. Jakarta : Departemen Kesehatan Republik Indonesia. Hal. 6.
Ditjen POM. (2014). Farmakope Indonesia. Edisi kelima. Jakarta : Departemen Kesehatan Republik Indonesia. Hal. 1343, 1348, 1359.
Hajar, S., Fitriana, F., & Asmaliani, I. (2023). Antibacterial Activity Test of Tembelekan Leaf Ethanol Extract (Lantana camara L) Against Bacteria Causing Gastrointestinal Tract Infections. Makassar Pharmaceutical Science Journal (MPSJ), 1(2), 76-85. mpsj/article/view/51/30
Ismawan, Bambang. (2010). 100 Plus Herbal Indonesia Bukti Ilmiah & Racikan. Jakarta : PT. Trubus Swadaya. Hal. 608 - 611.
Maryono, M., Muharram, M., & Salempa, P. (2015). Skrining Fitokimia Beberapa Fraksi Klroform dari Daun Lantana Camara Linn. CHEMICA" Jurnal Ilmiah Kimia dan Pendidikan Kimia", 16(1), 84-90.
Ningsih, W., Firmansyah, F., & Anggraini, S. (2016). Formulasi dan uji aktivitas antibakteri gel pembersih tangan ekstrak etanol daun kembang bulan (Tithonia Diversifolia (hemsley) A. Gray). Jurnal Ilmiah Farmasi, 12(2). https://journal.uii.ac.id/JIF/article/view/8801
Robinson, T. (1995). Kandungan Organik Tumbuhan Tinggi. Edisi VI. Institut Teknologi Press. Bandung. Hal. 71.
Sari, Retno. Dewi Isadiartuti. (2006). Studi Efektivitas Sediaan Gel Antiseptik Tangan Ekstrak Daun Sirih (Piper betle Linn). Fakultas Farmasi. Univesitas Airlangga. Surabaya. 77-81.
Surjowardojo, P., Susilawati, T. E., & Sirait, G. R. (2015). Daya hambat dekok kulit apel manalagi (Malus sylvestrs Mill.) terhadap pertumbuhan Staphylococcus aureus dan Pseudomonas sp. penyebab mastitis pada sapi perah. TERNAK TROPIKA Journal of Tropical Animal Production, 16(2), 40-48. https://doi.org/10.21776/ub.jtapro.2015.016.02.6
Tranggono, R.I. Fatma Latifah. (2007). Buku Pegangan Ilmu Pengetahuan Kosmetik. Jakarta : Penerbit Pustaka Utama. Hal. 6-8, 11, 19-20, 90.
Volk, W. A., & Wheeler, M. F. (1990). Mikrobiologi Dasar Jilid 2. Erlangga, Jakarta.
Wasitaatmaja, S.M. (1997). Penuntun Ilmu Kosmetik. Medik. Jakarta : UI-Press. Hal. 3,58-59, 62-63, 111-112.
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