Anti-Fungal Activity Testing of Purple Cabbage (Brassica oleracea Linn.) Ethanol Extract in Inhibiting The Fungi Growth Candida albicans and Malassezia furfur
DOI:
10.29303/jbt.v24i4.8009Published:
2024-11-15Downloads
Abstract
One of the plants that has the potential to be utilized as medicine is purple cabbage (Brassica oleracea Linn.). Commensal fungi like Candida albicans and Malassezia furfur can be found in the genitourinary tract, vagina, urethra, skin, fingers, and toes, among other places on the body. The purpose of: The study aimed to learn more about the antifungal properties of the ethanol extract of purple cabbage in preventing the growth of Malassezia furfur and Candida albicans. This study used an experimental design to examine the independent variables of the purple cabbage extract with various doses of the growth activity test of Candida albicans and Malassezia furfur, as well as their inhibition zones. Purple cabbage contains steroids, saponins, tannins, and flavonoid compounds. With concentrations of 10%, 20%, 30%, and positive control, the average diameter of the inhibitory zone for Candida albicans was 4.83 mm, 7.2mm, 8.75mm, and 6.21mm. The concentrations of Malassezia furfur at 10%, 20%, 30%, and the positive control were 4.61mm, 6.36mm, 8.83mm, and 6.15mm, respectively. As a negative control, DMSO failed to exhibit an inhibitory zone. Statistics revealed a substantial difference, indicating that the concentration had an impact on how the inhibition zone developed. The ethanol extract of purple cabbage has antifungal action, and the treatment with the 30% extract concentration forms the optimal concentration. It is advised that more research be done on the antifungal activity of purple cabbage extract against various kinds of fungus and that dosage forms be created for it.
Keywords:
Antifungal, Candida albicans, Malassezia furfur¸ purple cabbage.References
Alfiah, R. R., Khotimah, S., & Turnip, M. (2015). Efektivitas ekstrak metanol daun sembung rambat (Mikania micrantha Kunth) terhadap pertumbuhan jamur Candida albicans. Jurnal protobiont, 4(1). https://jurnal.untan.ac.id/index.php/jprb/article/view/8735
Departemen Kesehatan Republik Indonesia. (2000). Parameter Standar Umum Ekstrak Tumbuhan Obat. Jakarta: Direktorat Jendral Pengawasan Obat dan Makanan.
Depkes RI. (1995). Materia Medika Indonesia. Jilid VI Jakarta Dep Kesehat RI.
Diana, N., & Siti Khotimah, M. (2014). Penghambatan Pertumbuhan Jamur Fusarium oxysporum Schlecht Pada Batang Padi (Oryza sativa L.) Menggunakan Ekstrak Metanol Umbi Bawang Mekah (Eleutherine palmifolia Merr.). Protobiont, 3(2). https://jurnal.untan.ac.id/index.php/jprb/article/view/6829
Ditjen POM. (1979). Farmakope Indonesia. Jilid III. Dep Kesehat RI. 1979;9.
Indrayati, S., & Sari, R. I. (2018). Gambaran Candida albicans pada bak penampung air di toilet SDN 17 Batu Banyak Kabupaten Solok. Jurnal Kesehatan Perintis (Perintis's Health Journal), 5(2), 133-138. https://doi.org/10.33653/jkp.v5i2.148
Junaedi, D. R., & Salim, S. (2013). Efektivitas Ekstrak Daun Senggani (Melastoma candidum D. Don) dalam Menghambat Pertumbuhan C andida albicans pada Resin Akrilik Heat Cured (The Effectiveness of Senggani Leaves (Melastoma candidum D. Don) Extract for Inhibiting Growth of Candida albican s on Heat Cured Acrylic Resin). Journal of Prosthodontics, 4(1), 8-13.
LIPI. Tanaman Obat (Kolesterol). UPT: Balai Informasi Teknologi LIPI; 2009. 2,3,4.
Lolok, N., Awaliyah, N., & Astuti, W. (2020). Formulasi dan uji aktivitas sediaan sabun cair pembersih kewanitaan ekstrak daun waru (Hibiscus tiliaceus) terhadap jamur Candida albicans. Jurnal Mandala Pharmacon Indonesia, 6(01), 59-80. https://doi.org/10.35311/jmpi.v6i01.53
Mardiah, M., & Fatmawati, A. (2020). Penggunaan Serbuk Infus Bekatul Sebagai Bahan Baku Bekatul Dextrosa Agar Untuk Pertumbuhan Jamur. Jurnal Ilmu Alam dan Lingkungan, 11(1). https://journal.unhas.ac.id/index.php/jai2/article/view/9310
Mbatu, R. S. T., Kenanda, I. P. B., Suharta, I. G. Y., & Rita, W. S. (2018). Aktivitas Minyak Atsiri Daun Cengkeh Sebagai Antijamur Terhadap Candida albicans. Jurnal Media Sains, 2(1). https://doi.org/10.36002/jms.v2i1.360
Panden, T., Pelealu, J. J., & Singkoh, M. (2019). Uji Bioaktivitas Ekstrak Etanol Alga Merah Galaxaura oblongata (Ellis dan Solonder) Lamouroux. Terhadap Beberapa Jenis Bakteri Patogen.(Bioactivity Test of Red Algae Galaxaura oblongata (Ellis and Solonder) Lamouroux Ethanol Extract Against Several Types of Pathogenic Bacteria. JURNAL BIOS LOGOS, 9(2), 67-75. https://doi.org/10.35799/jbl.9.2.2019.24371
Pratiwi, S. T. (2008). Mikrobiologi farmasi. Jakarta: Erlangga, 95, 191.
Prayitno, Y. H. (2015). Uji Aktivitas Antifungal Ekstrak Metanol Mentah Rimpang Jeringau Merah (Acorus Calamus Linn.) terhadap Pertumbuhan Malassezia Furfur secara In Vitro terhadap Pertumbuhan Malassezia Furfur secara In Vitro terhadap Pertumbuhan Malassezia Furfur secara In VI. Jurnal Mahasiswa PSPD FK Universitas Tanjungpura, 3(1).
Sa'adah, H., & Nurhasnawati, H. (2015). Perbandingan pelarut etanol dan air pada pembuatan ekstrak umbi bawang tiwai (Eleutherine americana Merr) menggunakan metode maserasi. Jurnal ilmiah manuntung, 1(2), 149-153. https://doi.org/10.51352/jim.v1i2.27
Sadariah Husen, P., & Yunus, R. (2018). Uji Daya Hambat Perasan Lengkuas Merah (Alpinia Purpurata K Schum) Terhadap Pertumbuhan Jamur Penyakit Panu (Malassezia Furfur) Dengan Konsentrasi Yang Berbeda Menggunakan Metode Difusi Kertas Cakram (Paper disk) (Doctoral dissertation, Poltekkes Kemenkes Kendari).
Schwartz JR, DeAngelis YM, Dawson Jr TL. (2003). Dandruff and Seborrheic Dermatitis: A Head Scratcher. Pract Mod hair Sci. 1:1.
Simatupang, M. M. (2009). Candida albicans. Skripsi. Departemen Mikrobiologi Fakultas Kedokteran Universitas Sumatera Utara. Sumatera Utara.
Syamsul, E. S., Anugerah, O., & Supriningrum, R. (2020). Penetapan Rendemen Ekstrak Daun Jambu Mawar (Syzygium Jambos L. Alston) Berdasarkan Variasi Konsentrasi Etanol Dengan Metode Maserasi. Jurnal Riset Kefarmasian Indonesia, 2(3), 147-157. https://doi.org/10.33759/jrki.v2i3.98
Winastri, N. L. A. P., Muliasari, H., & Hidayati, E. (2020). Aktivitas antibakteri air perasan dan rebusan daun calincing (Oxalis corniculata L.) terhadap Streptococcus mutans. Berita Biologi, 19(2), 223-230. 10.14203/beritabiologi.v19i2.3786
Yuningsih, R. (2012). Pengobatan tradisional di unit pelayanan kesehatan. Info Singkat Kesejahteraan Sosial, 4(5), 9-12.
License
Copyright (c) 2024 Tetty Noverita Khairani, Khairani Fitri, Muhammad Andry, Paska Eli Sarumaha
This work is licensed under a Creative Commons Attribution 4.0 International License.
Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.
The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.
Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.
