Development of Conventional Tablets from Herbal Extracts of Jati Belanda, Kumis Kucing, Meniran, Sirih, and Turmeric for Body Weight Reduction
DOI:
10.29303/jbt.v24i4.8020Published:
2024-11-25Downloads
Abstract
Health problems that occur today are diverse and varied, one of which is being overweight. This study focuses on the formulation of herbal extracts in conventional tablet preparations using Jati Belanda, Kumis Kucing, Meniran, Sirih, and Kunyit which have the potential as weight loss agents. Extraction is carried out using the maceration method, then the extract is made into conventional tablets with additional ingredients: magnesium stearate, talc, PVP, Avicel pH 102, and aerosil. Evaluation of physical properties such as uniformity of size, uniformity of weight, hardness, and disintegration time has been carried out. The results of the study showed that conventional tablet preparations from various spices with 3 different formulations were successful. However, the results of the tablet hardness test have not met existing standards. The danger is the lack of PVP (Polyvinylpyrrolidone) excipients in the granules which cause the tablets to become brittle. To improve the formulation, the addition of the moisturizing agent can be done.
Keywords:
Conventional tablet, Herbal extract, weight loss, tablet formulationur.References
Banjarnahor, R. O., Banurea, F. F., Panjaitan, J. O., Pasaribu, R. S. P., & Hafni, I. (2022). Faktor-faktor risiko penyebab kelebihan berat badan dan obesitas pada anak dan remaja: Studi literatur. Tropical Public Health Journal, 2(1), Article 1. https://doi.org/10.32734/trophico.v2i1.8657
Fauziah, N., Maulidiyah, M., Putri, S. N. D., Amilia, H., Veronica, F. P., Khotimah, A. K., Anggrayni, R., Rahmawati, D., & Ambari, Y. (2024). Formulasi Tablet Menggunakan Metode Granulasi Basah. OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan, 2(4).
Husain, A., Tendean, L., & Queljoe, E. D. (2015). Pengaruh Kelebihan Berat Badan / Overweight Terhadap Terjadinya Disfungsi Seksual Pria. Jurnal e-Biomedik, 3(3). https://doi.org/10.35790/ebm.3.3.2015.10143
Kementerian Kesehatan RI. (2020). Farmakope Indonesisa (VI). Kementerian Kesehatan Republik Indonesia.
Marwati, A. D., Yulianto, A. N., & Setiyabudi, L. (2020). Formulasi dan Evaluasi Sifat Fisik Tablet Hisap Kombinasi Ekstrak Daun Bakau Hitam (Rhizophora mucronata) dan Vitamin C sebagai Antioksidan. Jurnal Ilmiah JOPHUS : Journal Of Pharmacy UMUS, 2(01), Article 01. https://doi.org/10.46772/jophus.v2i01.270
Mayefis, D., & Bidriah, M. (2022). Formulasi Sediaan Tablet Effervescent Ekstrak Herbal Meniran (Phyllantus niruri L) dengan Variasi Konsentrasi Sumber Asam dan Basa. Ahmar Metastasis Health Journal, 2(2), Article 2. https://doi.org/10.53770/amhj.v2i2.122
Mulyono, T. (2021). Penerapan Teknologi Mesin Penepung Rempah—Rempah Bagi Pengrajin Wedang Rempah di Desa Pandean Lamper Kecamatan Gayamsari, Kota Semarang, Jawa Tengah. Jurnal Hilirisasi Technology kepada Masyarakat, 2(2).
Okta, O. N. H., Rahmawati, D., Meliana, M., Jalmav, A., & Ambari, Y. (2024). Analisa mutu tablet ibuprofen generik berlogo dan generik bermerek yang diproduksi industri X di Gresik. Sasambo Journal of Pharmacy, 5(2), 101–108. https://doi.org/10.29303/sjp.v5i2.388
Rahim, B., Mertiza Fitri Muliani, Amanda, R., Eylidarson, F. B., Az-zahira, G., & Anggreini, O. (2023). Manfaat Taman Rempah Bagi Masyarakat Dalam Kehidupan Sehari-hari Melalui Program KKN Di Kelurahan Bungus Barat: Manfaat Taman Rempah. J-CoSE: Journal of Community Service & Empowerment, 1(2), 92–100. https://doi.org/10.58536/j-cose.v1i2.69
Rahmasiah, Hadiq, S., & Sirajuddin, W. (2024). Evaluasi Penggunaan Obat Tradisional Berdasarkan Dimensi Ketepatan Cara Penggunaan. Jurnal Farmasi IKIFA, 3(2).
Sulastri, T., Sunyoto, M., Suwitono, M. R., & Levita, J. (2022). The effect of red ginger bread consumption on the physiological parameters of healthy subjects. Journal of Advanced Pharmacy Education and Research, 12(3–2022), Article 3–2022. https://doi.org/10.51847/mznq1HW7vK
Wahyuni, F., Opod, H., & David, L. (2016). Hubungan tingkat kepercayaan diri dengan obesitas pada siswa-siswi SMA Negeri 7 Manado. Jurnal e-Biomedik, 4(1). https://doi.org/10.35790/ebm.4.1.2016.12144
Widyastuti, I., Luthfah, H. Z., Hartono, Y. I., Islamadina, R., Can, A. T., & Rohman, A. (2020). Antioxidant Activity of Temulawak (Curcuma xanthorrhiza Roxb.) and its Classification with Chemometrics. Indonesian Journal of Chemometrics and Pharmaceutical Analysis, 29. https://doi.org/10.22146/ijcpa.507
Zaman, N. N., & Sopyan, I. (2020). Tablet Manufacturing Process Method and Defect of Tablets. Majalah Farmasetika, 5(2). https://doi.org/10.24198/mfarmasetika.v5i2.26260
License
Copyright (c) 2024 Stephanie Angelica Rinjani Tampubolon, Marvel Reuben Suwitono, Titin Sulastri
This work is licensed under a Creative Commons Attribution 4.0 International License.
Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.
The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.
Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.
