The Association Between Allergic Rhinitis and Chronic Suppurative Otitis Media
DOI:
10.29303/jbt.v25i2.8880Published:
2025-04-26Downloads
Abstract
Tympanic membrane perforation and continuous discharge are hallmarks of chronic suppurative otitis media, a chronic inflammation of the middle ear. Through the malfunction of the Eustachian tube brought on by allergic inflammation, allergic rhinitis may contribute to the development of CSOM. This study aimed to analyze the relationship between allergic rhinitis and CSOM, identify common allergens, and assess the association between eosinophil levels and CSOM. A case-control study was conducted at RSUP H. Adam Malik and RS Murni Teguh Medan involving 72 participants: 36 CSOM patients and 36 healthy controls. Skin prick tests (SPT) and eosinophil counts were used to assess allergic status. Statistical analysis used Chi-square and Fisher’s exact test with significance set at p < 0.05. The results showed a significant association between allergic rhinitis and CSOM (p = 0.001; OR = 6.192). Common allergens found in CSOM patients were D. pteronyssinus (66.7%), D. farinae (63.9%), and cockroach (47.2%), with significant associations (p < 0.05). No significant relationship was found between allergic rhinitis and CSOM sides or type (p > 0.05). Elevated eosinophil levels were more common in the CSOM group but were not statistically significant (p = 0.624). In conclusion, allergic rhinitis is significantly associated with CSOM. Allergen screening is recommended for CSOM patients to improve diagnosis, treatment, and recurrence prevention.
Keywords:
Allergic rhinitis, CSOM, eosinophils, indoor allergens, skin prick test.References
Afriana, A., Syabriansyah, S., & Dita, D. A. A. (2023). Profile of allergic rhinitis and its association with chronic suppurative otitis media. Muhammadiyah Medical Journal, 4(2), 64–71. https://doi.org/10.24853/mmj.4.2.64-71
Bakhshaee, M., Rajati, M., Fereidouni, M., Khadivi, E., & Varasteh, A. (2011). Allergic rhinitis and chronic suppurative otitis media. European Archives of Oto-Rhino-Laryngology, 268(1), 87–91. https://doi.org/10.1007/s00405-010-1290-3
Byeon, H. (2019). Risk of otitis media associated with allergic rhinitis: A nationwide cohort study. International Journal of Pediatric Otorhinolaryngology, 117, 107843. https://doi.org/10.1016/j.ijporl.2018.11.012
Daud, M. K. M., Din, L. S., & Ahmad, M. S. A. (2019). Chronic suppurative otitis media and allergy: Is there a link? Malaysian Journal of Medicine and Health Sciences, 15(1), 76–81. https://medic.upm.edu.my/upload/dokumen/201912121151245_MJMHS_15(S1)76.pdf
Goniotakis, I., Perikleous, E., Fouzas, S., Steiropoulos, P., & Paraskakis, E. (2023). A clinical approach of allergic rhinitis in children. Children, 10(9), 1571.
Gorgulu, O., Ozelci, M., Suleyman, O., Mehmet, Y., Olgun, M. K., & Arikan, O. K. (2012). The role of allergy in the pathogenesis of chronic suppurative otitis media. International Advances in Otology, 8(2), 276–281. https://www.advancedotology.org/Content/files/sayilar/78/276-281.pdf
Guo, Z., Ji, W., Song, P., Zhao, J., Yan, M., Zou, X., ... & Song, L. (2024). Global, regional, and national burden of hearing loss in children and adolescents, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021. BMC Public Health, 24(1), 2521.
Hasanah, K. N. (2019). Peran rinitis alergi terhadap kekambuhan otitis media supuratif kronik. Universitas Diponegoro. https://eprints.undip.ac.id/69609/
Katre, P., & Harkare, V. (2017). Epidemiological study of factors influencing incidence of chronic suppurative otitis media in paediatric age group of rural population. Panacea Journal of Medical Sciences, 7(1), 35-39.
Mansour, S., Magnan, J., Nicolas, K., Haidar, H., Mansour, S., Magnan, J., ... & Haidar, H. (2018). Chronic suppurative otitis media (CSOM): a middle ear mucosal disease. Middle Ear Diseases: Advances in Diagnosis and Management, 205-274.
Natarajan, N., Batts, S., & Stankovic, K. M. (2023). Noise-induced hearing loss. Journal of clinical medicine, 12(6), 2347.
Onifade, A., Katolo, H. W., Mookerjee, S., & Bhutta, M. F. (2025). Epidemiology of Chronic Suppurative Otitis Media: Systematic Review To Estimate Global Prevalence. Journal of Epidemiology and Global Health, 15(1), 1-12.
Yani, W. S. H. P., & Djamin, R. (2018). Karakteristik dan faktor risiko otitis media supuratif kronik pada pasien di RS Wahidin Sudirohusodo periode Januari–Desember 2017. Jurnal Ilmu Kesehatan Makassar, 8(1), 45–50.
License
Copyright (c) 2025 Yohana Simanjutak, Devira Zahara, Ferryan Sofyan, Taufik Ashar

This work is licensed under a Creative Commons Attribution 4.0 International License.

Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.
The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.
Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.























