Literature Review: Extraction Methods and Antioxidant Activity of Rhizophora mucronata Leaves

Kalisa Attaya; Legis Ocktaviana Saputri; Lina Permatasari

doi:10.29303/jbt.v25i2.8949

Literature Review: Extraction Methods and Antioxidant Activity of Rhizophora mucronata Leaves

Authors

Kalisa Attaya , Legis Ocktaviana Saputri , Lina Permatasari

DOI:

10.29303/jbt.v25i2.8949

Published:

2025-05-26

Issue:

Vol. 25 No. 2 (2025): April-Juni

Keywords:

antioxidant activity, extraction, DPPH, Rhizophora mucronata, solvent

Articles

Downloads

How to Cite

Attaya, K., Saputri, L. O., & Permatasari, L. (2025). Literature Review: Extraction Methods and Antioxidant Activity of Rhizophora mucronata Leaves. Jurnal Biologi Tropis, 25(2), 2062–2067. https://doi.org/10.29303/jbt.v25i2.8949

Download Citation

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Abstract

Free radicals are highly reactive molecules and can trigger various degenerative diseases, so prevention efforts are needed through effective antioxidants. This study aims to review and analyze the extraction method of R. mucronata leaves in increasing antioxidant activity against DPPH free radicals. This study was conducted through a literature review of experimental research articles obtained from Google Scholar and PubMed databases using specific keywords, covering national and international publications for the period 2015-2025. The obtained articles were analyzed based on the extraction technique, solvent type, and IC₅₀ value reported in the article. The analysis showed that cold extraction methods, especially multi-step maceration with methanol solvent, can produce R. mucronata leaf extracts with very strong antioxidant activity with an IC₅₀ value of 0.04 ppm. The conclusion of this study confirms that extraction technique and solvent selection can affect the antioxidant activity of R. mucronata leaves. These findings support the need for optimization of extraction methods to maximize antioxidant effectiveness in the development of natural antioxidants.

References

Ahmad Kalija, T., & Imam Prayitno, D. (2020). Komponen Bioaktif dan Aktivitas Antioksidan Ekstrak Kasar Kerang Ale-Ale (Metetrix Sp.). Jurnal Laut Khatulistiwa, 3(1), 10-13. http://jurnal.untan.ac.id/index.php/lk

Akasia, A. I., Putra, I. D. N. N., & Putra, I. N. G. (2021). Skrining Fitokimia Ekstrak Daun Mangrove Rhizophora mucronata dan Rhizophora apiculata yang Dikoleksi dari Kawasan Mangrove Desa Tuban, Bali. Journal of Marine Research And Technology, 4(1), 16–22. https://ojs.unud.ac.id/index.php/JMRT

Anggarani, M. A., Ilmiah, M., & Mahfudhah, D. N. (2023). Literature Review of Antioxidant Activity of Several Types of Onions and Its Potensial as Health Supplements. Indonesian Journal of Chemical Science, 12(1), 103–111. http://journal.unnes.ac.id/sju/index.php/ijcs

Annas, Z. F., Muliasari, H., Deccati, R. F., Permatasari, L., & Mukhlishah, N. R. I. (2023). Penentuan kadar flavonoid total ekstrak dan fraksi-fraksi daun mangrove (Avicennia marina). Jurnal Agrotek Ummat, 10(3), 271–282.

Bulan, D. E., Nurfadilah, N., Syahrir, M. R., Mismawati, A., Torambung, A. K., & Rachmawati, M. (2022). Phytochemical Composition and Antioxidant Activity of Leaf Extracts from Three Rhizophora Species from Bontang Waters, Indonesia. Tropical Journal of Natural Product Research, 6(8), 1178–1182. https://doi.org/10.26538/tjnpr/v6i8.2

Candra, L. M. M., Andayani, Y., & Wirasisya, D. G. (2021). Pengaruh Metode Ekstraksi Terhadap Kandungan Fenolik Total dan Flavonoid Total Pada Ekstrak Etanol Buncis (Phaseolus vulgaris L.). Jurnal Pijar Mipa, 16(3), 397–405. https://doi.org/10.29303/jpm.v16i3.2308

Chelliah, C. K., Murugan, M., Rajivgandhi, G., Gnanasekaran, C., Govindan, R., Maruthupandy, M., Quero, F., Arulraj, A., Viswanathan, M. R., Alharbi, N. S., & Alshammary, N. H. (2023). Phytochemical derivatives and secondary metabolites rich Rhizophora mucronata as an active anti-oxidant and anti-bacterial agent against multi drug resistant bacteria. Journal of King Saud University - Science, 35(8). https://doi.org/10.1016/j.jksus.2023.102912

Delta, M., Rozirwan, & Hendri, M. (2021). Aktivitas Antioksidan Ekstrak Daun dan Kulit Batang Mangrove Sonneratia Alba di Tanjung Carat, Kabupaten Banyuasin, Provinsi Sumatera Selatan. Maspari Journal, 13(2), 129–144. https://doi.org/10.36706/maspari.v13i2.14577

Dotulong, V., Montolalu, L., & Reo, A. (2024). Aktivitas Antioksidan Daun Muda Mangrove Sonneratia alba Segar Asal Pesisir Desa Wori Sulawesi Utara. Media Teknologi Hasil Perikanan, 32–40. https://doi.org/10.35800/mthp.12.1.2024.51673

Endarini, L. H. (2016). Farmakognisi dan Fitokimia.

Hasan, H., Andy Suryadi, A. M., Bahri, S., & Widiastuti, N. L. (2023). Penentuan Kadar Flavonoid Daun Rumput Knop (Hyptis capitata Jacq.) Menggunakan Spektrofotometri UV-Vis. Journal Syifa Sciences and Clinical Research, 5(2). https://doi.org/10.37311/jsscr.v5i2.19371

Hidayah, H.A., Alifvira, M.D., Sukarsa, dan Al Hakim, R. R. (2022). Studi Etnobotani sebagai Obat Tradisional Masyarakat di Desa Adat Kalisalak, Banyumas, Jawa Tengah. Life Science, 11(1), 1–12.

Indriaty, Djufri, Ginting, B., & Hasballah, K. (2023). Phytochemical screening, phenolic and flavonoid content, and antioxidant activity of Rhizophoraceae methanol extract from Langsa, Aceh, Indonesia. Biodiversitas, 24(5), 2865–2876. https://doi.org/10.13057/biodiv/d240541

Jomova, K., Raptova, R., Alomar, S. Y., Alwasel, S. H., Nepovimova, E., Kuca, K., & Valko, M. (2023). Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging. In Archives of Toxicology (Vol. 97, Issue 10, pp. 2499–2574). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/s00204-023-03562-9

Kasitowati, R. D., Yamindago, A., & Safitri, M. (2017). Potensi Antioksidan dan Skrining Fitokimia Ekstrak Daun Mangrove Rhizophora mucronata, Pilang Probolinggo. Journal of Fisheries and Marine Science, 1(1), 72–77. http://jfmr.ub.ac.id

Martemucci, G., Costagliola, C., Mariano, M., D’andrea, L., Napolitano, P., & D’Alessandro, A. G. (2022). Free Radical Properties, Source and Targets, Antioxidant Consumption and Health. Oxygen, 2(2), 48–78. https://doi.org/10.3390/oxygen2020006

Ngibad, K. (2023). Aktivitas Antioksidan, Kadar Fenolik, dan Kadar Flavonoid Total Daun Jati Cina (Senna alexandrina). Lantanida Journal, 11(1), 24–35.

Permatasari, L., Riyanto, S., & Rohman, A. (2019). Baccaurea racemosa (Reinw. ex Blume) Müll. Arg. pulp: A potential natural antioxidant. Food Research, 3(6), 713–719. https://doi.org/10.26656/fr.2017.3(6).165

Ridlo, A., Pramesti, R., Koesoemadji, K., Supriyantini, E., & Soenardjo, N. (2017). Aktivitas Antioksidan Ekstrak Daun Mangrove Rhizopora mucronata. Buletin Oseanografi Marina, 6(2), 110. https://doi.org/10.14710/buloma.v6i2.16555

Sammanta, R. V., Permatasari, L., Muliasari, H., Rachmalia Izzatul Mukhlishah, N., & Fersiyana Deccati, R. (2024). Determination of Total Flavonoid Content from Extract and Fractions of Mangrove Leaves (Rhizopora mucronata). Acta Chimica Asiana, 7(2), 502–508. https://doi.org/10.29303/aca.v7i2.199

Senduk, T. W., Montolalu, L. A. D. Y., & Dotulong, V. (2020). The rendement of boiled water extract of mature leaves of mangrove Sonneratia alba). Jurnal Perikanan Dan Kelautan Tropis, 11(1), 9–15. https://ejournal.unsrat.ac.id/index.php/JPKT/index

Usman, U., Masruhim, M. A., Kusumaningtiyas, P., Erwin, E., & Bulan, D. E. (2023). Antioxidant and Antidiabetic from Rhizophora mucronata Derived from Sambera Beach, East Kalimantan, Indonesia. Tropical Journal of Natural Product Research, 7(10), 4921–4926. https://doi.org/10.26538/tjnpr/v7i10.31

Vittaya, L., Charoendat, U., Janyong, S., Ui-eng, J., & Leesakul, N. (2022). Comparative analyses of saponin, phenolic, and flavonoid contents in various parts of Rhizophora mucronata and Rhizophora apiculata and their growth inhibition of aquatic pathogenic bacteria. Journal of Applied Pharmaceutical Science, 12(11), 111–121. https://doi.org/10.7324/JAPS.2022.121113

Wulandari, J., Harmain, R. M., & Dali, F. A. (2022). Aktivitas antioksidan pada daun mangrove api-api (Avicennia marina). Jurnal Ilmiah Perikanan Dan Kelautan, 10(1), 7–16.

Yuliantari, N. W. A., Widarta, I. W. R., & Permana, I. D. G. M. (2017). Pengaruh Suhu dan Waktu Ekstraksi Terhadap Kandungan Flavonoid dan Aktivitas Antioksidan Daun Sirsak (Annona muricata L.) Menggunakan Ultrasonik. Media Ilmiah Teknologi Pangan (Scientific Journal of Food Technology), 4(1), 35–42.

Yulianti, W., Ayuningtyas, G., Martini, R., & Resmeiliana, I. (2020). Pengaruh Metode Ekstraksi dan Polaritas Pelarut Terhadap Kadar Fenolik Total Daun Kersen (Muntingia calabura L). Jurnal Sains Terapan, 10(2), 41–49. https://doi.org/10.29244/jstsv.10.2.41-49

Zhang, Q. W., Lin, L. G., & Ye, W. C. (2018). Techniques for extraction and isolation of natural products: A comprehensive review. In Chinese Medicine (United Kingdom) (Vol. 13, Issue 1). BioMed Central Ltd. https://doi.org/10.1186/s13020-018-0177-x

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.

The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.

Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.

Most read articles by the same author(s)

Alma Dyah Perwita, Adam Trojan Alisyahbana, Adinda Ilsa Maulida, Alfia Mawaddah, Ali Ramzi, Legis Ocktaviana Saputri, The Marine Organisms as Potential Sources of Inhibits ACE on Hypertension Patient , Jurnal Biologi Tropis: Vol. 23 No. 1 (2023): Special Issue
Gina Tasya Rizka Hafizah, Agriana Rosmalina Hidayati, Lina Permatasari, Comparative Analysis of a Secondary Metabolite Profile from Leaves, Peel and Bulbs of Allium sativum L. by GC-MS , Jurnal Biologi Tropis: Vol. 24 No. 3 (2024): July - September
Cintya Budastra, Tuhfatul Ulya, Selvira Anandia Intan Maulidya, Indra Purnomo, Baiq Risky Wahyu Lisnasari, Lina Permatasari, Literature Review: Exploration of Bioactive Components of Avicennia marina and Its Biological Activities , Jurnal Biologi Tropis: Vol. 24 No. 1b (2024): Special Issue
Made Raditya Arhya Putra, Legis Ocktaviana Saputri, Teguh Budi Wicaksono, Kadek Nandita Nugraha, Ajeng Ayu Putri, Rika Kamila Salsabila, Puspa Zalika Fidelia, Marine Organisms with Anti-Amyloid Effect Through Their Role as BACE1 Inhibitors for Preventive Effort in Alzheimer’s Disease: A Literature Review , Jurnal Biologi Tropis: Vol. 24 No. 4 (2024): Oktober - Desember
Juhratul Istiqamah, Lina Permatasari, Nisa Isneni Hanifa, Antioxidant Activity Testing of Fractions Resulting from Gravity Column Chromatography of Methanol Extract of Kepundung Leaves (Baccaurea racemosa) Using The DPPH Method , Jurnal Biologi Tropis: Vol. 24 No. 4 (2024): Oktober - Desember
Aji Alfian G. M, Bulkaini Bulkaini, Djoko Kisworo, Ichsan Ichsan, A. Rosyidi, Enny Yuliani, Lina Permatasari, Analysis of Cholesterol Content, E. Coli Bacteria, and Organoleptic Value of Rarang Chicken Cooking Based on Slaughter Age , Jurnal Biologi Tropis: Vol. 24 No. 4 (2024): Oktober - Desember
Mutia Novisma, Legis Ocktaviana Saputri, Nisa Isneni Hanifa, In Vivo Analgetic Activity Test of Malacca Stem Bark Extract (Phyllanthus emblica L.) by Acetic Acid Induction Method , Jurnal Biologi Tropis: Vol. 24 No. 4 (2024): Oktober - Desember
Fitri Nazilinly, Lina Permatasari , Nurmi Hasbi, Antibacterial Activity of Ethyl Asetate Fraction of Centella asiatica Against Clinical Isolates of Pseudomonas aeruginosa , Jurnal Biologi Tropis: Vol. 24 No. 3 (2024): July - September
Ray Haerul Wardani, Lina Permatasari, Agriana Rosmalina Hidayati, Nisa Isneni Hanifa, DPPH Radical Capture Test of Sumbawa Oil and Identification of Compound Content Using GC-MS , Jurnal Biologi Tropis: Vol. 25 No. 1 (2025): Januari - Maret
Naela Rosida, Lina Permatasari, Wahida Hajrin, The Sun Protection Factor (SPF) of Kepundung Leaf Methanol 96% Extract (Baccaurea racemosa) Using The In-Vitro Test , Jurnal Biologi Tropis: Vol. 24 No. 2b (2024): Special Issue

Literature Review: Extraction Methods and Antioxidant Activity of Rhizophora mucronata Leaves

Authors

DOI:

Published:

Issue:

Keywords:

Articles

Downloads

How to Cite

Downloads

Metrics

Abstract

References

License

Most read articles by the same author(s)

Similar Articles

Menu

Manuscript Template

visitor

Keywords

Mitra Kerja sama

Open Access Journals

Contact Us

Information

Share & Follow