Physical Stability Evaluation of Topical Formulation Containing Turmeric (Curcuma longa L.) Leaf Extract as a Potential Natural Repellent
DOI:
10.29303/jbt.v25i3.9341Published:
2025-07-10Downloads
Abstract
Turmeric (Curcuma longa L.) leaves, rich in bioactive compounds like tannins, terpenoids, and essential oils, have potential as a mosquito repellent for preventing vector-borne diseases such as dengue, filariasis, and malaria. This study aimed to evaluate the physical stability of repellent lotion formulations containing ethanol extract of turmeric leaves. The research was experimental in nature. Two formulations were prepared using extract concentrations of 10% (F1) and 20% (F2). The turmeric leaves were extracted using the maceration method with 96% ethanol, yielding 4.069%. The physical stability of the repellent lotion was tested using the freeze-thaw method over 12 days, evaluating organoleptic properties, homogeneity, pH, adhesion, and spreadability. Organoleptic testing showed color differences between the formulas. After stability testing, the consistency of the lotions became slightly thinner. Both formulations exhibited good homogeneity. The pH values were within the safe range for skin application. Changes in adhesion and spreadability were influenced by the testing process. In conclusion, the repellent lotion formulations containing turmeric leaf ethanol extract demonstrated good physical stability and met required quality standards.
Keywords:
formulation, lotion, physical stability, repellent, turmeric leafReferences
Abdika, A. (2017). Efektivitas dan karakteristik lotion minyak sereh wangi (Cymbopogon nardus L.) sebagai repelan nyamuk.
Agustin, V. D. (2020). Formulasi dan karakterisasi sediaan hand and body lotion ekstrak daun salam (Syzygium polyanthum) dengan perbandingan asam stearat sebagai emulgator [Karya tulis ilmiah, Fakultas Farmasi Institut Ilmu Kesehatan Bhakti Wiyata].
Ambari, Y., & Suena, N. M. D. S. (2019). Uji stabilitas fisik formulasi lotion anti nyamuk minyak sereh. Jurnal Ilmiah Medicamento, 5(2), 111–118.
Aseptianova. (2019). Pengaruh ekstrak daun kunyit (Curcuma longa Linn.) sebagai insektisida elektrik terhadap mortalitas nyamuk Culex sp. [Laporan ilmiah].
Aisyah, R., & Supriyanto, E. (2017). Pengaruh ekstrak daun kunyit terhadap pH dan warna permen jelly. Jurnal Pangan dan Agroindustri, 5(3), 39–48.
Dominica, D., & Handayani, D. (2019). Formulasi dan evaluasi sediaan lotion dari ekstrak daun lengkeng (Dimocarpus longan) sebagai antioksidan. Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 6(1), 3–5.
Fatikhatunnida, E., Sari, W. Y., & Ramadhan, M. F. (2022). Formulasi dan evaluasi lotion repellent nyamuk kombinasi minyak atsiri daun jeruk purut serta serai wangi.
Herlina, T., & Fitriana, L. (2018). Pengaruh siklus pembekuan-pencairan terhadap stabilitas fisik emulsi W/O (water in oil) dengan pengemulsi polisorbat 80 dan Span 80. Jurnal Farmasi Indonesia, 10(2), 108–116.
Justicia, A. K., Wildaniah, W., & Ganda, K. (2019). Pengaruh jenis emulgator terhadap kestabilan fisik lotion repelan nyamuk ekstrak etanol bunga kenanga (Cananga odorata L.). Akademi Farmasi Yarsi Pontianak, Kalimantan Barat.
Kariani, I. A. B. (2022). Aktivitas larvasida ekstrak etanol daun kunyit (Curcuma longa Linn.) terhadap larva nyamuk Aedes aegypti [Karya tulis ilmiah].
Kristianingsih, I., & Febriana, I. N. (2022). Formulasi sediaan repellent lotion kombinasi ekstrak etanol daun kemangi (Ocimum sanctum L.) dan ekstrak sereh (Cymbopogon nardus L. Rendle). Fakultas Farmasi, Institut Ilmu Kesehatan Bhakti Wiyata Kediri.
Lestari, W., & Andayani, T. (2019). Uji efektivitas lotion kombinasi ekstrak daun pandan (Pandanus amaryllifolius Rox.) dan daun salam koja (Murraya koenigii L. Spreng) sebagai repellent Aedes aegypti. Journal of Healthcare Technology and Medicine, 5(2). Universitas Ubudiyah Indonesia.
Lumentut, N. (2020). Formulasi dan uji stabilitas fisik sediaan krim ekstrak etanol kulit buah pisang goroho (Musa acuminata L.) konsentrasi 12,5% sebagai tabir surya. Fakultas MIPA, Universitas Sam Ratulangi.
Pratiwi, L., Fudholi, A., Martien, R., & Pramono, S. (2018). Uji stabilitas fisik dan kimia sediaan SNEDDS (self-nanoemulsifying drug delivery system) dan nanoemulsi fraksi etil asetat kulit manggis (Garcinia mangostana L.).
Septiana, E., & Simanjuntak, P. (2015). Aktivitas antimikroba dan antioksidan ekstrak beberapa bagian tanaman kunyit (Curcuma longa Linn.). Jurnal Fitofarmaka, 5(1), 31–40.
Sofi, N. S., Nurhayati, G. S., Effendi, E., Indriatmoko, D. D., & Yusransyah. (2021). Formulasi dan aktivitas lotion antinyamuk Aedes aegypti dari ekstrak kulit buah limus (Mangifera foetida Lour). Jurnal Ilmiah Kesehatan Delima, 4(2), 78–90.
Stiani, S. N., Nurhayati, G. S., Effendi, E., Indriatmoko, D. D., & Yusransyah. (2021). Formulasi dan aktivitas lotion antinyamuk Aedes aegypti dari ekstrak kulit buah limus (Mangifera foetida Lour). Jurnal Ilmiah Kesehatan Delima, 4(2), 78–90.
Sudaryati, S., & Purnomo, H. (2017). Pengaruh alat ekstraksi terhadap kandungan senyawa bioaktif dan rendemen ekstrak daun jambu biji (Psidium guajava L.). Jurnal Ilmu Kefarmasian Indonesia, 15(1), 21–28.
Tamrin, M. (2022). Studi literatur penetapan rendemen ekstrak etanol tumbuhan suku Myrtaceae menggunakan metode maserasi. Karya Tulis Ilmiah, 15.
Widya, R., Oktaviany, F., & Maghfirandi, R. (2018). Efektivitas etanol kulit jeruk manis (Citrus × aurantium L.) sebagai larvasida terhadap larva nyamuk Aedes aegypti.
Yuliansi, W. (2020). Formulasi dan uji efektivitas sediaan lotion antinyamuk minyak sereh (Citronella oil) [Karya tulis ilmiah].
Yuliarsih, E. (2010). Uji efektivitas losion repelan minyak mimba terhadap nyamuk Aedes aegypti. Universitas Islam Jakarta.
Yulistiyaningsih, E., Legowo, D. B., & Safitri, C. I. N. H. (2021). Formulasi dan stabilitas mutu fisik losion pencerah dari minyak atsiri kunyit putih (Curcuma mangga Val.). Artikel pemakalah paralel.
Yuniarti, N. A. (2018). Efektivitas perasan bawang daun (Allium fistolosum Linn.) terhadap mortalitas larva Aedes sp. Universitas Muhammadiyah Surabaya.
License
Copyright (c) 2025 Tuhfatul Ulya, Titin Ratnasari, En Purmafitriah, Anisa Sasvania
This work is licensed under a Creative Commons Attribution 4.0 International License.
Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.
The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.
Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.
