Radiologic Features and Prognosis of Gastric Perforation

I Putu Aryana Kusuma Putra; Inayah Wulandari; Shira Shalsabina Shafitri

doi:10.29303/jbt.v25i4.10132

Radiologic Features and Prognosis of Gastric Perforation

Authors

I Putu Aryana Kusuma Putra , Inayah Wulandari , Shira Shalsabina Shafitri

DOI:

10.29303/jbt.v25i4.10132

Published:

2025-10-13

Issue:

Vol. 25 No. 4 (2025): in Progress

Keywords:

Diagnostic imaging, gastric perforation, MDCT, radiology, prognosis.

Articles

Downloads

pdf

How to Cite

Putra, I. P. A. K., Inayah Wulandari, & Shira Shalsabina Shafitri. (2025). Radiologic Features and Prognosis of Gastric Perforation. Jurnal Biologi Tropis, 25(4), 5498–5505. https://doi.org/10.29303/jbt.v25i4.10132

Download Citation

Downloads

Download data is not yet available.

Abstract

Gastric perforation carries high rates of morbidity and mortality, making it a critical surgical emergency. This systematic review presents recent evidence of radiological imaging, including its evaluation for the diagnosis of gastric perforation and its effect on patient prognosis. The search strategy included an extensive literature review from online databases, including PubMed and Google Scholar, with key phrases (such as "gastric perforation" and "diagnostic imaging"). A qualitative synthesis was done to evaluate the diagnostics of different imaging techniques and prognostic factors. The most relevant result is that Multidetector Computed Tomography (MDCT) continues to be the golden test, showing 82-90% accuracy in detecting perforation based on identifiable characteristics of the extraluminal free air. In summary, gastric perforation is a life-threatening condition where quick, accurate diagnosis with MDCT is vital for better outcomes, as delays exceeding 24 hours significantly raise mortality risk. This review highlights the importance of integrating MDCT into clinical protocols to speed up diagnosis and treatment, ultimately enhancing patient survival.

References

AL Zoubi, M., El-Matbouly, M. A., Suliman, A. M., & AlBahrani, A. Z. (2022). Atypical cases of gastric perforation due to ischemia: Case series and review of literature. Journal of Surgery 7(6). https://doi.org/10.29011/2575-9760.001499

Andrian, A., Ikhsan, R., & Siregar, W. Y. (2022). Laporan kasus: Perforasi gaster. Averrous: Jurnal Kedokteran dan Kesehatan Malikussaleh, 8(1), 81–87. https://doi.org/10.29103/averrous.v8i1.7051

Assefa, G., Makuach, B., Tabor, B. B., & Hailu, S. S. (2025). Spontaneous gastric perforation in a 6-year-old child: A rare case report. Annals of Medicine & Surgery, 87 (7), 4672–4675. https://doi.org/10.1097/ms9.0000000000003443

Baca-Arzaga, A. A., Navarro-Chavez, H., Galindo, J., Santibanez-Juarez, J., Cardosa-Gonzalez, C., & Flores-Villalba, E. (2019). Transjejunal laparoscopic assisted ERCP in a patient with Roux-en-Y hepaticojejunostomy. Medicina (Lithuania), 55(8). https://doi.org/10.3390/medicina5508048

Bini, R., Ronchetta, C., Picotto, S., Scozzari, G., Gupta, S., Frassini, S., & Chiara, O. (2020). Importance of CT scan predicting clinical outcomes in gastrointestinal perforation. Annals of Translational Medicine, 8(21), 1421.

https://doi.org/10.21037/atm-20-2184

Celik, H., Kamar, M. A., Altay, C., Basara Akin, I., & Secil, M. (2022). Accuracy of specific free air distributions in predicting the localization of gastrointestinal perforations. Emergency Radiology, 29(1), 99–105. https://doi.org/10.1007/s10140-021-01990-7

Chen, T. Y., Liu, H. K., Yang, M. C., Yang, Y. N., Ko, P. J., Su, Y. T., Huang, R. Y., & Tsai, C. C. (2018). Neonatal gastric perforation: A report of two cases and a systematic review. Medicine (United States), 97(17). https://doi.org/10.1097/MD.0000000000010369

Del Gaizo, A. J., Lall, C., Allen, B. C., & Leyendecker, J. R. (2014). From esophagus to rectum: A comprehensive review of alimentary tract perforations at computed tomography. Abdominal Imaging, 39 (4), 802–823. https://doi.org/10.1007/s00261-014-0110-4

Drakopoulos, D., Arcon, J., Freitag, P., El-Ashmawy, M., Lourens, S., Beldi, G., Obmann, V. C., Ebner, L., Huber, A. T., & Christe, A. (2021). Correlation of gastrointestinal perforation location and amount of free air and ascites on CT imaging. Abdominal Radiology, 46 (10), 4536–4547. https://doi.org/10.1007/s00261-021-03128-2

Heo, S., Huh, J., Kim, J. K., & Lee, K. M. (2025). Delayed perforation after endoscopic resection of upper gastrointestinal tumors. Journal of Clinical Gastroenterology, 59(6), 542–548. https://doi.org/10.1097/MCG.0000000000002037

Huang, Y., Lu, Q., Peng, N., Wang, L., Song, Y., Zhong, Q., & Yuan, P. (2021). Risk factors for mortality in neonatal gastric perforation: A retrospective cohort study. Frontiers in Pediatrics, 9, 652139. https://doi.org/10.3389/fped.2021.652139

Huerta, C. T., & Perez, E. A. (2022). Diagnosis and management of neonatal gastric perforation: A narrative review. Digestive Medicine Research, 5, 27. https://doi.org/10.21037/dmr-21-105

Iacusso, C., Boscarelli, A., Fusaro, F., Bagolan, P., & Morini, F. (2018). Pathogenetic and prognostic factors for neonatal gastric perforation: Personal experience and systematic review of the literature. Frontiers in Pediatrics, 6. https://doi.org/10.3389/fped.2018.00061

Jain, N., Ratan, S. K., Ch, M., Neogi, S., Kumar, C., & Kumar, P. (2023). Neonatal gastric perforation: Review of 5 years’ experience in a tertiary care centre. Shasanka Shekhar Panda International Journal of Scientific Research Paediatric Surgery. https://doi.org/10.36106/ijsr

Jung, K., Woo, S.-Y., Kim, A. R., & Kim, H. (2023). Upper gastrointestinal tract perforation assessed by contrast-enhanced ultrasonography after oral Sonazoid administration in a stomach leakage mouse model. Ultrasonography, 42(2), 297–306. https://doi.org/10.14366/usg.22192

Kobayashi, T., Tabuchi, S., Koganezawa, I., Nakagawa, M., Yokozuka, K., Ochiai, S., Gunji, T., Ozawa, Y., Sano, T., Tomita, K., Chiba, N., Hidaka, E., & Kawachi, S. (2024). Early identification of patients with potential failure of nonoperative management for gastroduodenal peptic ulcer perforation. Digestive Surgery, 41(1), 24–29. https://doi.org/10.1159/000535520

Koto, K., Asrul, A., & A, M. (2016). Characteristic of gastric perforation type and the histopathology at Haji Adam Malik General Hospital Medan-Indonesia. Bali Medical Journal, 5(1), 186. https://doi.org/10.15562/bmj.v5i1.325

Kulinna-Cosentini, C., Hodge, J. C., & Ba-Ssalamah, A. (2024). The role of radiology in diagnosing gastrointestinal tract perforation. Best Practice & Research Clinical Gastroenterology, 70, 101928. https://doi.org/10.1016/j.bpg.2024.101928

Lanas, A., & Chan, F. K. L. (2017). Peptic ulcer disease. The Lancet, 390 (10094), 613–624. https://doi.org/10.1016/S0140-6736(16)32404-7

Lone, Y. A., Singh, S. K., Naaz, A., Chetan, C., & Kashyap, S. V. (2024). Tiny tummies, big challenges: A case series of neonatal gastric perforations. Cureus.

https://doi.org/10.7759/cureus.58149

Mahadevan, V. (2020). Anatomy of the stomach. Surgery (Oxford), 38(11), 683–686. https://doi.org/10.1016/j.mpsur.2020.08.005

Pouli, S., Kozana, A., Papakitsou, I., Daskalogiannaki, M., & Raissaki, M. (2020). Gastrointestinal perforation: Clinical and MDCT clues for identification of etiology. Insights into Imaging, 11(1). https://doi.org/10.1186/s13244-019-0823-6

Romano, S., Somma, C., Sciuto, A., Jutidamrongphan, W., Pacella, D., Esposito, F., Puglia, M., Mauriello, C., Khanungwanitkul, K., & Pirozzi, F. (2022). MDCT findings in gastrointestinal perforations and the predictive value according to the site of perforation. Tomography, 8(2), 667–687. https://doi.org/10.3390/tomography8020056

Sinnathamby, A., Low, J. M., Dale Lincoln Ser Keng, L., & Yvonne Peng Mei, N. (2021). Watch your numbers! Avoiding gastric perforation from feeding tubes in neonates. Pediatrics and Neonatology, 62 (6), 681–682. https://doi.org/10.1016/j.pedneo.2021.06.011

Søreide, K. (2016). Current insight into the pathophysiology of gastroduodenal ulcers: Why do only some ulcers perforate? Journal of Trauma and Acute Care Surgery, 80(6), 1045–1048. https://doi.org/10.1097/TA.0000000000001035

Sureka, B., Bansal, K., & Arora, A. (2015). Pneumoperitoneum: What to look for in a radiograph? Journal of Family Medicine and Primary Care, 4 (3), 477. https://doi.org/10.4103/2249-4863.161369

Velde, G., Ismail, W., & Thorsen, K. (2024). Perforated peptic ulcer. British Journal of Surgery, 111(9). https://doi.org/10.1093/bjs/znae224

Weledji, E. P. (2020). An overview of gastroduodenal perforation. Frontiers in Surgery, 7. https://doi.org/10.3389/fsurg.2020.573901

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.

The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.

Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.

Radiologic Features and Prognosis of Gastric Perforation

Authors

DOI:

Published:

Issue:

Keywords:

Articles

Downloads

How to Cite

Downloads

Abstract

References

License

Similar Articles

Menu

Manuscript Template

visitor

Keywords

Mitra Kerja sama

Open Access Journals

Contact Us

Information

Share & Follow