Identification of Bioactive Solutions of Corn Silk (Zea mays L.) Extract and Biological Activity Test By Bioinformatics

Afdhal  Raihan; Angga Kurnia Illahi; Siti  Rokhimah; Tasya Putri Pratama Elisa; Rita Maliza

doi:10.29303/jbt.v23i1.5846

Identification of Bioactive Solutions of Corn Silk (Zea mays L.) Extract and Biological Activity Test By Bioinformatics

Authors

Afdhal Raihan , Angga Kurnia Illahi , Siti Rokhimah , Tasya Putri Pratama Elisa , Rita Maliza

DOI:

10.29303/jbt.v23i1.5846

Published:

2023-11-08

Issue:

Vol. 23 No. 1 (2023): Special Issue

Keywords:

Anti-bacterial, anti-inflammatory, anti-oxidant, corn silk.

Articles

Downloads

pdf

How to Cite

Raihan, A. ., Illahi, A. K., Rokhimah, S. ., Elisa, T. P. P., & Maliza, R. (2023). Identification of Bioactive Solutions of Corn Silk (Zea mays L.) Extract and Biological Activity Test By Bioinformatics. Jurnal Biologi Tropis, 23(1), 245–250. https://doi.org/10.29303/jbt.v23i1.5846

Download Citation

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Abstract

Corn silk (Zea mays L.) is an agricultural by-product that is discarded as agricultural waste. Corn silk has secondary metabolite compounds that have the potential to become useful bioactive compounds. The purpose of this study is to recognize the bioactive potential of corn hair through compound identification and biological activity. The method used is preparation and extraction by maceration method followed by identification of compounds through LC-MS analysis method and Phytochemical test, bioinformatic PASS test based on data through PubChem, ChemSpider, and way2drug web. The results obtained from corn silk have a group of active compounds, including alkaloids, flavonoids, saponins, steroids and triterpenoids. Analysis of potential bioactivity received Acaciin compounds have high antioxidant bioactivity with a Pa value of 0.815, 2-arachidonoylglycerol has high potential antiinflammatory bioactivity with a Pa value of 0.736 and 1,2-di-O-methyl-4-[(2R)-2,4-dihydro butyramide shows moderate possible antibacterial activity with a Pa value of 0.643. This study concludes that corn silk has high bioactive potential as an antioxidant, anti-inflammatory and antibacterial.

References

Amini, Fitrah. (2023). Optimasi Kombinasi Simplisia Buah Andaliman, Daun Sirsak, dan Kulit Manggis Sebagai Kandidat Obat Antikanker Payudara. Tesis. Program Studi Biokimia. Fakultas Matematika dan Ilmu Pengetahuan Alam. Institut Pertanian Bogor. Bogor. URL: https://repository.ipb.ac.id/handle/123456789/116009

Aukkanit, N., Kemngoen, T., & Ponharn, N. (2015). Utilization of corn silk in low fat meatballs and its characteristics. Procedia-Social and Behavioral Sciences, 197, pp.1403-1410. DOI: 10.1016/j.sbspro.2015.07.086

Arifin, H. A., Hashiguchi, T., Nagahama, K., Hashiguchi, M., Muguerza, M., Sakakibara, Y., Tanaka, H. (2021). Varietal Differences in Flavonoid and Antioxidant Activity in Japanese Soybean Accessions. Bioscience, Biotechnology, and Biochemistry. 85(4), 916-922. DOI: https://doi.org/10.1093/bbb/zbaa104

Cowan, S. W., Schirmer, T., Rummel, G., Steiert, M., Ghosh, R. A., Jansonius, J. N., & Rosenbusch, J. P. (1999). Crystal structure explain fuctional properties of two Escherichia Coliporin. Nature. 358, 722-33. DOI: 10.1038/358727a0

Fatimah, F., Martha, R. D., & Kusumawati, A. (2020). Deteksi dan Identifikasi Senyawa Flavonoid Ekstrak Etanol Kulit Batang Tanaman Majapahit (Crescentia cujete) dengan LCMS. CHEESA: Chemical Engineering Research Articles, 3(2), 88. DOI: https://doi.org/10.25273/cheesa.v3i2.7688.88-98

Filimonov, D. A., Lagunin, A. A., Gloriozova, T. A., Rudik, A. V., Druzhilovskii, D., & S., Pogodin, P. V., & Poroikov, V. V., (2014), Prediction of the biological activity spectra of organic compounds using the pass online web resource, Chemistry of Heterocyclic Compounds, 50(3), 444–457. DOI: https://doi.org/10.1007/s10593-014-1496-1

Fitriah, Aida. (2017). Analisis Interaksi Senyawa Flavonoid Sukun (Artocarpus altilis) Terhadap Reseptor Estrogen Alfa Secara In silico Sebagai Model Kandidat Antikanker Payudara. Skripsi. Jurusan Biologi. Fakultas Sains dan Teknologi. Universitas Islam Negeri Maulana Malik Ibrahim. Malang.

Himawan R. F. (2010). Kromatografi Cair Kinerja Tinggi (KCKT).

Jannah,A., Rachmawaty, D.U., & Maunatin. A. (2018). Uji Aktivitas Antibakteri Rambut Jagung Manis (Zea mays ssaccarata Strurt) terhadap Bakteri Staphylococcus aureus dan Escherichia coli. ALCHEMY: Journal of Chemistry, 5(4), 132-137. DOI: 10.18860/al.v5i4.4182

Hasanudin, K., Hashim, P.S., & Mustafa. (2012). Corn silk (Stigma maydis) in healthcare: A phytochemical and pharmacological review. Molecules 17, 9697–9715. DOI:10.3390/molecules17089697

Malikhana, A., Yuniastuti, A., R. Susanti., Nugrahaningsih, W. H. (2021). Studi In silico Potensi Senyawa Bioaktif Gembili (Dioscorea esculenta) Sebagai Ligan Pada Reseptor G6PD dan PTPN1. Prosiding Semnas Biologi ke-9. Fakultas Matematika dan Ilmu Pengetahuan Alam. Universitas Negeri Semarang.

Mangurana, W. O. I., Yusnaini., dan Sahidin. (2019). Analisis LC-MS/MS (Liquid Chromatography Mass Spectrometry) dan Metabolit Sekunder serta Potensi Antibakteri Ekstrak n-Heksana Spons Callyspongia aerizusa yang diambil pada kondisi tutupan Terumbu Karang yang berbeda di Perairan Teluk Staring. Jurnal Biologi Tropis, 19 (2) : 131 – 14.

Nessa, F., Ismail, Z., & Mohamed, N. (2012). Antimicrobial activities of extracts and flavonoid glycosides of corn silk (Zea mays L.) International journal of Biotechnology for Wellnes Industries,1, 115-121. DOI: 10.6000/1927-3037%2F2012.01.02.02

Oliver, S. P,. Gillespie, B. E., Lewis, M. J., Ivey, S. J., Almeida R. A., Luther, D. A., Jhonson, D. L., Lamar, K. C., Moorehead, H. D., & Dowlen, H. H. 2001. Efficacy of a new premilking teat disinfectan containing a phenolic combination for the prevention of mastitis. J. Dairy Sci. 84, 1545 – 1549. DOI: 10.3168/jds.s0022-0302(01)70189-0

Puspitarsari, Laode, Herman. (2018). Identifikasi Golongan Metabolit Sekunder dan Aktivitas Antioksidan Ekstrak Daun Brotowali (Tinospora tuberculata Beumee). ISTN. Jagakarsa Jakarta.

Rudi H. Paeru,S.P dan Trias Qurnia Dewi, S.P. (2012). Panduan Praktis Budidaya Jagung. Dok. Penebar Swadaya

Salsabila, S., Palupi, N.S. and Astawan, M., (2021). Potensi Rambut Jagung sebagai Minuman Fungsional. Jurnal Pangan, 30(2),pp.137-146. DOI: 10.33964/jp.v30i2.542

Solihah MA, Wan Rosli WI, Nurhanan AR. Phytochemicals screening and total phenolic content of Malaysian Zea mays hair extracts. International Food Research Journal, 2012, 19(4);1533–38. URL: http://eprints.usm.my/id/eprint/32493

Subroto, M, A., & H. Saputro. 2006. Gempur Penyakit dengan Sarang Semut. Jakarta: Penebar Swadaya.

Sudirman, S. 2011. Aktivitas Antioksidan dan Komponen Bioaktif Kangkung Air (Ipomoea aquatic forsk.). Fakultas Perikanan dan Ilmu Kelautan IPB.

Wedaswari IAI. (2018). Aktivitas Antioksidan Ekstrak Etanol dan Fraksi Daun Sirih Merah (Piper crocatum) Dengan Metode Rancimat dan Identifikasi dengan LC-MS.

Wijayanti, F., & Ramadhian, M, R. (2016). Efek rambut jagung (Zea mays) terhadap penurunan kadar kolesterol dalam darah. Majority, 5(3), 91-95.

Winarsi, H. (2007). Antioksidan Alami & Radikal Bebas. Yogyakarta: Kanisius

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.

The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.

Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.

Identification of Bioactive Solutions of Corn Silk (Zea mays L.) Extract and Biological Activity Test By Bioinformatics

Authors

DOI:

Published:

Issue:

Keywords:

Articles

Downloads

How to Cite

Downloads

Metrics

Abstract

References

License

Most read articles by the same author(s)

Similar Articles

Menu

Manuscript Template

visitor

Keywords

Mitra Kerja sama

Open Access Journals

Contact Us

Information

Share & Follow