The Potential of Black Cumin (Nigella sativa) as an Immunostimulant in Aquaculture (Review)
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Nuri Muahiddah , Damai DiniariwisanDOI:
10.29303/jbt.v24i2.6762Published:
2024-05-29Issue:
Vol. 24 No. 2 (2024): April - JuniKeywords:
Akuakultur, imunostimulan, imun non-spesifik, Nigella Sativa.Articles
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Abstract
Research on the use of black cumin (Nigella sativa) as an immunostimulant in aquaculture has shown interesting potential. In this review, we explore the potential of black cumin as an immunostimulant in aquatic animals. Based on a recent literature review, we highlight the positive effects of black cumin extract in enhancing immune responses in aquatic organisms. The active compounds in black cumin, such as thymoquinone and α-hederin, are thought to have the ability to stimulate the immune system, increase cytokine production, and increase phagocytic activity. Implications of using black cumin in aquaculture include the potential to improve the health and productivity of aquatic animals. However, challenges such as dose optimization, effectiveness in various aquatic species, and environmental risk management need to be addressed. Suggestions for further research include more in-depth studies of the mechanism of action, clinical trials on various aquatic species, as well as environmental impact assessments. With a careful and coordinated approach, the use of black cumin as an immunostimulant has the potential to increase sustainability and productivity in aquaculture practices.
References
Altunoglu, Y. C., Bilen, S., Ulu, F., & Biswas, G. (2017). Immune responses to methanolic extract of black cumin (Nigella sativa) in rainbow trout (Oncorhynchus mykiss). Fish & shellfish immunology, 67, 103-109. https://doi.org/10.1016/j.fsi.2017.06.002Get rights and content
Amanulloh, M., & Krisdayanti, E. (2019). Jintan Hitam sebagai Imunomodulator dan Anti Inflamasi pada Pasien Asma. Jurnal Penelitian Perawat Profesional, 1(1), 115-120. DOI: https://doi.org/10.37287/jppp.v1i1.32
Bahri, A. (2021). Pengaruh Perendaman Ekstrak Etanol Daun Kersen (Muntingia Calabura) Untuk Pengobatan Infeksi Jamur Saprolegnia Sp Pada Benih Ikan Lele (Clarias Gariepinus) (Doctoral dissertation, Universitas Islam Riau).
Bektaş, Z. H., Savaşer, S., Akçimen, U., Ceylan, M., Yener, O., & Bulut, C. (2019). Using of black cumin seed powder (Nigella sativa) as immunostimulant and growth promoter in rainbow trout, Oncorhynchus mykiss (Walbaum). Turkish Journal of Fisheries and Aquatic Sciences, 19(12), 987-999. 10.4194/1303-2712-v19_12_01
Fadeifard, F., Raissy, M., Jafarian, M., Boroujeni, H. R., Rahimi, M., & Faghani, M. (2018). Effects of black seed (Nigella sativa), ginger (Zingiber officinale) and cone flower (Echinacea angustifolia) on the immune system of rainbow trout, Oncorhynchus mykiss. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 70, 199-204. https://doi.org/10.1590/1678-4162-8489
Gustiana, G., Rantetondok, A., & Zainuddin, E. N. (2015). Efektivitas Ekstrak Biji Jintan Hitam (Nigella Sativa Linn.) Terhadap Infeksi Bakteri Streptococcus Agalactiae Pada Ikan Nila (Oreochromis Niloticus Linn.). Torani Journal of Fisheries and Marine Science, 25(1). DOI: https://doi.org/10.35911/torani.v25i1.258
Ir Harlina, M. P. (2023). Monograf Potensi Bahan Alami Dalam Peningkatan Sistem Imun Udang Vaname. Nas Media Pustaka.
Jamil, A. S., Adi, B., Prasaja, B., Ariani, A., & Hardi, Z. (2014). Aktivitas antimikroba ekstrak biji Nigella sativa terhadap viabilitas bakteri probiotik secara in vitro dan in vivo. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 11(2).
Hermawan, G. (2017). Gambaran Sensitifitas Produk Minyak Jintan Hitam (Nigella Sativa) Terhadap Pertumbuhan Bakteri Salmonella Typhi (Studi Di Kecamatan Jombang Kabupaten Jombang) (Doctoral dissertation, STIKES Insan Cendekia Medika Jombang).
Hidayat, R., & Harpeni, E. (2014). Profil Hematologi Kakap Putih (Lates calcallifer) yang Distimulasi dengan Jintan Hitam (Nigela sativa) dan Efektifitasnya Terhadap Infeksi Vibrio alginolyticus. e-Jurnal Rekayasa dan Teknologi Budidaya Perairan, 3(1), 327-334.
Khusan, D. N. (2022). Pengaruh Perbedaan Dosis Penambahan Tepung Jintan Hitam (Nigella Sativa) Pada Pakan Buatan Terhadap Pertumbuhan Dan Kelangsungan Hidup Ikan Nila Salin (Oreochromis niloticus) (Doctoral dissertation, Universitas Pekalongan).
Minjoyo, H., Prihaningrum, A., Rivaie, A. R., & Dharmawanti, V. (2021). Growth Performance And Immune Response Of Silver Pompano Seeds (Trachinotus Blocii) Fed With Feed Containing Immunostimulant Supplements. e-Jurnal Rekayasa dan Teknologi Budidaya Perairan, 9(2), 1117-1130.
Muahiddah, N., & Asri, Y. (2024). Pengaruh Penggunaan Eucheuma Cottonii Sebagai Imunostimulan Pada Bidang Akuakultur. Ganec SWARA, 18(1), 575-582. DOI: https://doi.org/10.35327/gara.v18i1.797
Muahiddah, N., & Dwiyanti, S. (2023). Penggunaan Kulit Manggis (Garcinia Mangostana) Sebagai Imunostimulan Dalam Bidang Akuakultur (Artikel Review). Ganec Swara, 17(3), 1154-1159. DOI: https://doi.org/10.35327/gara.v17i3.556
Muahiddah, N., & Isnansetyo, A. (2024). Pemberian Fucoidan Secara Oral Dari Hasil Ekstraksi Sargassum sp. Untuk Menanggulangi Motile Aeromonad Septicemia Pada Ikan Lele (Clarias sp.). Jurnal Riset Akuakultur, 18(3), 197-206. DOI: http://dx.doi.org/10.15578/jra.18.3.2023.197-206
Nurchollifah, Y., Wijayatri, R., & Hidayat, I. W. (2021, December). Literature Study Of Pharmacological Effects Of Black Seed (Nigella Sativa) Based On Active Seeds. In Prosiding University Research Colloquium (pp. 815-832).
Sa'adah, R., Sasanti, A. D., & Taqwa, F. H. (2015). Aplikasi tepung jintan hitam (Nigella sativa) untuk pencegahan infeksi bakteri Streptococcus agalactiae pada ikan nila (oreochromis niloticus). Jurnal Akuakultur Rawa Indonesia, 3(1), 58-69. DOI: https://doi.org/10.36706/jari.v3i1.4404
Sasanti, A. D. (2014). Efektivitas Tepung Jintan Hitam (Nigella sativa) untuk Mencegah Infeksi Aeromonas hydrophila pada Ikan Patin. Jurnal Akuakultur Rawa Indonesia, 2(2), 188-201. DOI: https://doi.org/10.36706/jari.v2i2.2103
Perwitasari, C. (2020). Review Analisis Kualitas Air Ikan Kerapu Tikus Yang Terinfeksi VNN Dengan Perlakuan Protein Rekombinan Chlorella vulgaris (Doctoral dissertation, Universitas Brawijaya).
Wirawan, I. K. A., Suryani, S. A. M. P., & Arya, I. W. (2018). Diagnosa, analisis dan identifikasi parasit yang menyerang ikan nila (Oreochromis niloticus) pada Kawasan Budidaya Ikan Di Subak “Baru” Tabanan. Gema Agro, 23(1), 63-78.
Yanuhar, U. (2019). Budi Daya Ikan Laut" Si Cantik Kerapu". Universitas Brawijaya Press.
Yousefi, M., Adineh, H., Reverter, M., Hamidi, M. K., Vatnikov, Y. A., Kulikov, E. V., & Van Doan, H. (2021). Protective effects of black seed (Nigella sativa) diet supplementation in common carp (Cyprinus carpio) against immune depression, oxidative stress and metabolism dysfunction induced by glyphosate. Fish & Shellfish Immunology, 109, 12-19. https://doi.org/10.1016/j.fsi.2020.11.032
Yunus, Y. E. (2021). Pengaruh Pemberian Ekstrak Tanaman Lidah Buaya (Aloe vera) Melalui Pakan Terhadap Performa Hematologi, Respon Imun dan Efek Anti Parasit Pada Ikan Nila (Oreochromis niloticus) (Doctoral dissertation, Universitas Hasanuddin).
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