Colorectal Cancer: The Impact of Smoking and Alcohol on Risk in West Nusa Tenggara, Treatment, and Prevention

Syahda Aqila Syakir; Arif Zuhan

doi:10.29303/jbt.v24i1b.8074

Colorectal Cancer: The Impact of Smoking and Alcohol on Risk in West Nusa Tenggara, Treatment, and Prevention

Authors

Syahda Aqila Syakir , Arif Zuhan

DOI:

10.29303/jbt.v24i1b.8074

Published:

2024-12-16

Issue:

Vol. 24 No. 1b (2024): Special Issue

Keywords:

Alcohol consumption, colorectal cancer, prevention, risk factors; smoking, treatment, West Nusa Tenggara.

Articles

Downloads

pdf

How to Cite

Syakir, S. A., & Arif Zuhan. (2024). Colorectal Cancer: The Impact of Smoking and Alcohol on Risk in West Nusa Tenggara, Treatment, and Prevention. Jurnal Biologi Tropis, 24(1b), 488–497. https://doi.org/10.29303/jbt.v24i1b.8074

Download Citation

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Abstract

: Colorectal cancer (CRC) is the third most common cancer globally and the second leading cause of cancer-related mortality. It results from complex interactions between genetic, environmental, and lifestyle factors, with smoking and alcohol consumption being significant contributors. This study focuses on the correlation between smoking and alcohol consumption with CRC incidence in West Nusa Tenggara (NTB), a province in Indonesia known for its high smoking prevalence (32.79%) and alcohol consumption rate (1.6%). A literature review methodology was employed, systematically collecting data from PubMed, ScienceDirect, Cochrane Library, Google Scholar, and ProQuest using keywords such as "colorectal cancer," "risk factors," "smoking," "alcohol," "management," and "prevention." A total of 35 articles published between 2007 and 2024 were analyzed to provide a comprehensive synthesis of CRC risk factors, management approaches, and prevention strategies. The findings reveal a strong association between smoking and CRC risk, particularly among middle-aged males, while alcohol amplifies the risk synergistically. Despite limited alcohol prevalence, its impact remains substantial. The study emphasizes the importance of targeted public health interventions in NTB, integrating lifestyle modification campaigns and routine screenings to mitigate CRC risks and improve health outcomes in high-risk communities.

References

Akhter, M., Kuriyama, S., Nakaya, N., Shimazu, T., Ohmori, K., Nishino, Y., Tsubono, Y., Fukao, A. and Tsuji, I. (2007) ‘Alcohol consumption is associated with an increased risk of distal colon and rectal cancer in Japanese men: the Miyagi Cohort Study.’, European journal of cancer (Oxford, England : 1990), 43(2), pp. 383–390. doi: 10.1016/j.ejca.2006.09.020.

Alzahrani, S. M., Al Doghaither, H. A. and Al-Ghafar, A. B. (2021) ‘General insight into cancer: An overview of colorectal cancer (review)’, Molecular and Clinical Oncology, 15(6). doi: 10.3892/MCO.2021.2433.

Aswan, N. R. and Hanriko, R. (2023) ‘Faktor Risiko Kanker Kolorektal Colorectal Cancer Risk Factors’, Medula, 13, pp. 1–6.

Aswan, N. R., Hanriko, R., Suwandi, J. F. and Wintoko, R. (2022) ‘Hubungan Konsumsi Daging Merah dengan Kanker Kolorektal Correlation Red Meat Consumption and Colorectal Cancer’, Jurnal Kesehatan dan Agromedicine, 9(2), pp. 140–145.

Badan Pusat Statistik Provinsi NTB (2022) Provinsi Nusa Tenggara Barat Dalam Angka 2022. Badan Pusat Statistik Provinsi Nusa Tenggara Barat.

Badan Pusat Statistik Provinsi NTB (2024) Persentase Penduduk Usia 15 Tahun Ke Atas yang Merokok dalam Sebulan Terakhir Menurut Kabupaten/Kota dan Kelompok Umur di Provinsi Nusa Tenggara Barat, 2023, Badan Pusat Statistik Provinsi NTB. Available at: https://ntb.bps.go.id/id/statistics-table/3/ZGxsdU15dEtNWEpNYmpCSUsyVkdaRnBpVkV0dVFUMDkjMw==/persentase-penduduk-usia-15-tahun-ke-atas-yang-merokok-dalam-sebulan-terakhir-menurut-kabupaten-kota-dan-kelompok-umur-di-provinsi-nusa-tenggara-barat--2023.html? (Accessed: 16 November 2024).

Botteri, E., Borroni, E., Sloan, E. K., Bagnardi, V., Bosetti, C., Peveri, G., Santucci, C., Specchia, C., van den Brandt, P., Gallus, S., and Lugo, A. (2020) ‘Smoking and Colorectal Cancer Risk, Overall and by Molecular Subtypes: A Meta-Analysis’, American Journal of Gastroenterology, 115(12), pp. 1940–1949. doi: 10.14309/ajg.0000000000000803.

Buccafusca, G., Proserpio, I., Tralongo, A. C., Rametta Giuliano, S., & Tralongo, P. (2019) ‘Early colorectal cancer: diagnosis, treatment and survivorship care’, Critical Reviews in Oncology/Hematology, 136(December 2018), pp. 20–30. doi: 10.1016/j.critrevonc.2019.01.023.

Dekker, E., Tanis, P. J., Vleugels, J. L. A., Kasi, P. M., & Wallace, M. B. (2019) ‘Colorectal cancer’, The Lancet, 394(10207), pp. 1467–1480. doi: 10.1016/S0140-6736(19)32319-0.

Gu, MJ., Huang, QC., Bao, CZ., Li, YJ., Li, XQ. And Ye, D. (2018) ‘Attributable causes of colorectal cancer in China.’, BMC cancer, 18(1), p. 38. doi: 10.1186/s12885-017-3968-z.

Hossain, M. S., Karuniawati, H., Jairoun, A. A., Urbi, Z., Ooi, J., John, A., Lim, Y. C., Kibria, K. M. K., Mohiuddin, A. K. M., Ming, L. C., Goh, K. W., and Hadi, M. A. (2022) ‘Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies’, Cancer, 14(1732), pp. 1–25. Available at: https://doi.org/10.3390/cancers14071732.

Jensen, K., Afroze, S., Munshi, M. K., Guerrier, M., & Glaser, S. S. (2012) ‘Mechanisms for nicotine in the development and progression of gastrointestinal cancers.’, Translational gastrointestinal cancer, 1(1), pp. 81–87. doi: 10.3978/j.issn.2224-4778.2011.12.01.

Kemenkes RI (2016) Panduan Penatalaksanaan Kanker kolorektal, Kementerian Kesehatan Republik Indonesia.

Kementerian Kesehatan Republik Indonesia (2023) Survei Kesehatan Indonesia 2023 Dalam Angka, Kota Kediri Dalam Angka. Available at: https://www.badankebijakan.kemkes.go.id/ski-2023-dalam-angka/.

Kim, B. J. and Hanna, M. H. (2023) ‘Colorectal cancer in young adults’, Journal of Surgical Oncology, 127(8), pp. 1247–1251. doi: 10.1002/jso.27320.

Lafay, L. and Ancellin, R. (2015) ‘Alimentation et cancer colorectal’, Cahiers de Nutrition et de Dietetique, 50(5), pp. 262–270. doi: 10.1016/j.cnd.2015.03.005.

Lansdorp-Vogelaar, I., van Ballegooijen, M., Zauber, A. G., Boer, R., Wilschut, J., Winawer, S. J., and Habbema, J. D. (2009) ‘Individualizing Colonoscopy Screening by Gender and Race’, Gastrointest Endosc., 27(3), pp. 320–331. doi: 10.1016/j.gie.2008.08.040.Individualizing.

Leufkens, A. M., Van Duijnhoven, F. J., Boshuizen, H. C., Siersema, P. D., Kunst, A. E., Mouw, T., Tjønneland, A., Olsen, A., Overvad, K., Boutron-Ruault, M. C., Clavel-Chapelon, F., Morois, S., Krogh, V., Tumino, R., Panico, S., Polidoro, S., Palli, D., Kaaks, R., Teucher, B., Pischon, T., and Bueno-de-Mesquita, H. B. (2012) ‘Educational level and risk of colorectal cancer in EPIC with specific reference to tumor location’, International Journal of Cancer, 130(3), pp. 622–630. doi: 10.1002/ijc.26030.

Lewandowska, A., Rudzki, G., Lewandowski, T., Stryjkowska-Góra, A., and Rudzki, S. (2022) ‘Risk Factors for the Diagnosis of Colorectal Cancer’, Cancer Control, 29, pp. 1–15. doi: 10.1177/10732748211056692.

Majid, S. R. and Ariyanti, F. (2020) ‘Determinan Kejadian Kanker Kolorektal’, Jurnal Ilmu Kesehatan Masyarakat, 9(04), pp. 208–215. doi: 10.33221/jikm.v9i04.677.

Mármol, I., Sánchez-de-Diego, C., Pradilla Dieste, A., Cerrada, E., and Rodriguez Yoldi, M. J. (2017) ‘Colorectal carcinoma: A general overview and future perspectives in colorectal cancer’, International Journal of Molecular Sciences, 18(1). doi: 10.3390/ijms18010197.

Moradi, T., Gridley, G., Björk, J., Dosemeci, M., Ji, B. T., Berkel, H. J., and Lemeshow, S. (2008) ‘Occupational physical activity and risk for cancer of the colon and rectum in Sweden among men and women by anatomic subsite’, European Journal of Cancer Prevention, 17(3), pp. 201–208. doi: 10.1097/CEJ.0b013e3282b6fd78.

Olén, O., Erichsen, R., Sachs, M. C., Pedersen, L., Halfvarson, J., Askling, J., Ekbom, A., Sørensen, H. T., and Ludvigsson, J. F. (2020) ‘Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study’, The Lancet, 395(10218), pp. 123–131. doi: 10.1016/S0140-6736(19)32545-0.

Pickhardt, P. J., Hassan, C., Halligan, S., and Marmo, R. (2011) ‘Colorectal cancer: CT colonography and colonoscopy for detection--systematic review and meta-analysis.’, Radiology, 259(2), pp. 393–405. doi: 10.1148/radiol.11101887.

Putranto, A. S. (2022) ‘Manajemen Kanker Kolorektal’, Medicinus, 35(3), pp. 3–10. doi: 10.56951/medicinus.v35i3.99.

Puzzono, M., Mannucci, A., Grannò, S., Zuppardo, R. A., Galli, A., Danese, S., and Cavestro, G. M. (2021) ‘The role of diet and lifestyle in early-onset colorectal cancer: A systematic review’, Cancers, 13(23), pp. 1–26. doi: 10.3390/cancers13235933.

Respatiadi, H. and Tandra, S. (2018) ‘Di Bawah Umur dan Ilegal:Konsumsi Alkohol dan Risiko Kesehatannya Bagi Anak-anak Muda Studi Kasus di Bandung, Jawa Barat’, Center for Indonesian Policy Studies. doi: https://doi.org/10.35497/270467.

Rompis, A. Y. and Dewi, N. N. A. (2019) ‘Aspek Genetik Kanker Kolorektal’, Aspek Genetik Kanker Kolorektal, 2, p. 10. Available at: https://jsk.farmasi.unmul.ac.id.

Sari, M. I., Wahid, I. and Suchitra, A. (2019) ‘Kemoterapi Adjuvan pada Kanker Kolorektal’, Jurnal Kesehatan Andalas, 8(1S), p. 51. doi: 10.25077/jka.v8i1s.925.

Sayuti, M. and Nouva, N. (2019) ‘Kanker Kolorektal’, AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh, 5(2), p. 76. doi: 10.29103/averrous.v5i2.2082.

Shah, I., Gawron, A. J., Byrne, K. R., and Inadomi, J. M. (2024) ‘Disparities in Colorectal Cancer Screening Among Asian American Populations and Strategies to Address These Disparities’, Gastroenterology, 166(4), pp. 549–552. doi: 10.1053/j.gastro.2024.02.009.

Shinji, S., Yamada, T., Matsuda, A., Sonoda, H., Ohta, R., Iwai, T., Takeda, K., Yonaga, K., Masuda, Y., & Yoshida, H. (2022) ‘Recent Advances in the Treatment of Colorectal Cancer: A Review’, Journal of Nippon Medical School, 89(3), pp. 246–254. doi: 10.1272/jnms.JNMS.2022_89-310.

Teixeira, M. C., Braghiroli, M. I., Sabbaga, J., and Hoff, P. M. (2014) ‘Primary prevention of colorectal cancer: myth or reality?’, World journal of gastroenterology, 20(41), pp. 15060–15069. doi: 10.3748/wjg.v20.i41.15060.

Willauer, A. N., Liu, Y., Pereira, A. A. L., Lam, M., Morris, J. S., Raghav, K. P. S., Morris, V. K., Menter, D., Broaddus, R., Meric-Bernstam, F., Hayes-Jordan, A., Huh, W., Overman, M. J., Kopetz, S., and Loree, J. M. (2019) ‘Clinical and molecular characterization of early-onset colorectal cancer’, PubMed Central, 14(4), pp. 535–562. doi: 10.1002/cncr.31994.Clinical.

Wong, M. C., Ding, H., Wang, J., Chan, P. S., and Huang, J. (2019) ‘Prevalence and risk factors of colorectal cancer in Asia’, Intestinal Research, 17(3), pp. 317–329. doi: 10.5217/ir.2019.00021.

Author Biography

Arif Zuhan

Digestive Surgery Division, Department of Surgery, General Hospital of West Nusa Tenggara Province – Faculty of Medicine, University of Mataram, Indonesia

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.

The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.

Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.

Colorectal Cancer: The Impact of Smoking and Alcohol on Risk in West Nusa Tenggara, Treatment, and Prevention

Authors

DOI:

Published:

Issue:

Keywords:

Articles

Downloads

How to Cite

Downloads

Metrics

Abstract

References

Author Biography

Arif Zuhan

License

Most read articles by the same author(s)

Similar Articles

Menu

Manuscript Template

visitor

Keywords

Mitra Kerja sama

Open Access Journals

Contact Us

Information

Share & Follow