Vol. 24 No. 1b (2024): Special Issue
Open Access
Peer Reviewed

Deep Vein Thrombosis (DVT): A Literature Review

Authors

Alya Syafa Kamila , Gintis Dhimar Ginuluh , Syahda Aqila Syakir , Aisya Nur Abida , Ananda Amirah Balqis , Fairuz Karlina , Rinesita Murniatin , Afif Farras , Al Fikar Raihan , Rian Akka Jaya Putra , Maz Isa Ansyori Arsyatt

DOI:

10.29303/jbt.v24i1b.8008

Published:

2024-12-16

Downloads

Abstract

Deep Vein Thromboembolism (DVT) occurs due to the formation of blood clots in the veins, characterized by the formation of thrombi along with an inflammatory response in the inner walls of the veins. DVT most commonly occurs in the deep veins of the lower extremities but can also occur, albeit less frequently, in other areas such as the arms or other forms of superficial thrombosis. This article aims to review the epidemiology, clinical presentation, diagnosis, pathophysiology, and management of deep vein thrombosis. The literature review was conducted by searching for relevant articles on deep vein thrombosis published in the past fifteen years. Literature searches were performed using Google Scholar, PubMed, and NCBI databases. The findings highlight the clinical manifestations of DVT and its potential to cause serious complications, particularly post-thrombotic syndrome. Post-thrombotic syndrome is a debilitating condition that can significantly impair patients' quality of life. Management of DVT involves both pharmacological and non-pharmacological treatments. Understanding the mechanisms of deep vein thrombosis and its management is crucial in minimizing the complications associated with this condition.

Keywords:

Deep Vein Thrombosis (DVT), diagnosis, patophysiology, treatment.

References

Adnyana, I.W.L., Suega, K., Bakta, I.M., 2015. Pendidikan Kedokteran Berkelanjutan (PKB) XXI 2015 TROMBOSIS VENA DALAM.

Andriani, R., & Wahid, I. (2018). Defisiensi Protein S pada Trombosis Vena Dalam. Jurnal Kesehatan Andalas, 7, 100. https://doi.org/10.25077/jka.v7i0.937

Azzahro, A.W., Mahmuda, I.N.N.M., 2020. Tantangan Dalam Diagnosis dan Manajemen Kasus DVT Persisten.

Azirar S, Appelen D, Prins MH, Neumann MH, de Feiter AN, Kolbach DN. Compression therapy for treating post-thrombotic syndrome. Cochrane Database Syst Rev. 2019 Sep 18;9(9):CD004177. doi: 10.1002/14651858.CD004177.pub2

Brill A. Multiple Facets of Venous Thrombosis. Int J Mol Sci. 2021 Apr 8;22(8):3853. doi: 10.3390/ijms22083853

CDC, 2020. Venous Thromboembolism (Blood Clots) [WWW Document]. URL https://www.cdc.gov/ncbddd/dvt/facts.html#:~:text=Deep vein thrombosis (DVT) is, also occur in the arm.

Cui, S., Chen, S., Heit, J.A., 2015. Epidemiology of venous thromboembolism. Nature Reviews Cardiology. Nat. Rev. Cardiol. 12, 464–474.

Etikasari, E., & Chayati, N. (2021). Screening risiko terjadinya deep vein trhombosis. Journal of Telenursing (JOTING), 3(2), 735–743. https://doi.org/10.31539/joting.v3i2.2836

Hungaro Cunha C, Yuri Sato D, Pereira de Godoy JM, da Silva Russeff GJ, Franccini Del Frari Silva D, Pereira de Godoy HJ, Menezes da Silva MO, Amorim Santos H, Guerreiro Godoy MF. Mortality and Deep Vein Thrombosis in the Gamma Variant of Covid 19 and Lung Injury. Vasc Health Risk Manag. 2022 Nov 3;18:833-838. doi: 10.2147/VHRM.S367930

Hutagalung, E. V., Sihite, T. A., & Prasetya, D. (2021). Karakteristik pasien trombosis vena dalam: Tinjauan sistematik. Journal of the Indonesian Medical Association, 71(4), 161–169. https://doi.org/10.47830/jinma-vol.71.4-2021-479

Jayanegara, A. P. (2016). Diagnosis dan Tatalaksana Deep Vein Thrombosis. Cermin Dunia Kedokteran, 43(9), 652–657. http://www.cdkjournal.com/index.php/CDK/article/download/859/605

Kahn SR. The post-thrombotic syndrome. Hematology Am Soc Hematol Educ Program. 2016 Dec 2;2016(1):413-418. doi: 10.1182/asheducation-2016.1.413

Kahn SR, Galanaud JP, Vedantham S, Ginsberg JS. Guidance for the prevention and treatment of the post-thrombotic syndrome. J Thromb Thrombolysis. 2016 Jan;41(1):144-53. doi: 10.1007/s11239-015-1312-5

Kim KA, Choi SY, Kim R. Endovascular Treatment for Lower Extremity Deep Vein Thrombosis: An Overview. Korean J Radiol. 2021 Jun;22(6):931-943. doi: 10.3348/kjr.2020.0675

Kushner, A., West, W.P., Suheb, M.Z.K., Leela, S.P., 2024. Virchow Triad [WWW Document]. StatPearls [Internet]. Treasure Isl. StatPearls Publ. URL https://www.ncbi.nlm.nih.gov/books/NBK539697/

Arum, I. A. (2017). Trombosis Vena Dalam. Unram Medical Journal, 2(1). https://doi.org/10.29303/jku.v2i1.55

Torbicki, A., Perrier, A., Konstantinides, S., Agnelli, G., Galiè, N., Pruszczyk, P., Bengel, F., Brady, A. J., Ferreira, D., Janssens, U., Klepetko, W., Mayer, E., Remy-Jardin, M., Bassand, J., Vahanian, A., Camm, J., De Caterina, R., Dean, V., Dickstein, K., Vachiery, J. (2018). Guidelines on the diagnosis and management of acute pulmonary embolism. European Heart Journal, 29(18), 2276–2315. https://doi.org/10.1093/eurheartj/ehn310

Pastori D, Cormaci VM, Marucci S, Franchino G, Del Sole F, Capozza A, Fallarino A, Corso C, Valeriani E, Menichelli D, Pignatelli P. A Comprehensive Review of Risk Factors for Venous Thromboembolism: From Epidemiology to Pathophysiology. Int J Mol Sci. 2023 Feb 5;24(4):3169. doi: 10.3390/ijms24043169

Pitaningrum, Y., Rahmat, B., Ermawan, R., 2019. Buku Ajar Ilmu Penyakit Jantung. PT. Percetakan Bali, Denpasar.

Rediputra, Andika. Peran Pemeriksaan D-Dimer Terhadap Diagnosis Trombosis. Jurnal Kedokteran, [S.l.], v. 2, n. 2, p. 436-453, june 2017. ISSN 2620-5890. Available at: https://ejournal.unizar.ac.id/index.php/kedokteran/article/view/621

Sobreira ML, Marques MÁ, Paschoa AF, Ribeiro AJA, Casella IB, Burihan MC, Matielo MF, Soares RA, de Araujo WJB, Joviliano EE, de Oliveira JCP. Guidelines on deep vein thrombosis of the Brazilian Society of Angiology and Vascular Surgery. J Vasc Bras. 2024 Sep 3;23:e20230107. doi: 10.1590/1677-5449.202301072

Streiff MB, Agnelli G, Connors JM, Crowther M, Eichinger S, Lopes R, McBane RD, Moll S, Ansell J. Guidance for the treatment of deep vein thrombosis and pulmonary embolism. J Thromb Thrombolysis. 2016 Jan;41(1):32-67. doi: 10.1007/s11239-015-1317-0

Xie J, Prats-Uribe A, Feng Q, Wang Y, Gill D, Paredes R, Prieto-Alhambra D. Clinical and Genetic Risk Factors for Acute Incident Venous Thromboembolism in Ambulatory Patients With COVID-19. JAMA Intern Med. 2022 Oct 1;182(10):1063-1070. doi: 10.1001/jamainternmed.2022.3858

Author Biographies

Alya Syafa Kamila, Universitas Mataram

Author Origin : Indonesia

Gintis Dhimar Ginuluh, Universitas Mataram

Author Origin : Indonesia

Syahda Aqila Syakir, Universitas Mataram

Author Origin : Indonesia

Aisya Nur Abida, Universitas Mataram

Author Origin : Indonesia

Ananda Amirah Balqis, Universitas Mataram

Author Origin : Indonesia

Fairuz Karlina, Universitas Mataram

Author Origin : Indonesia

Rinesita Murniatin, Universitas Mataram

Author Origin : Indonesia

Afif Farras, Universitas Mataram

Author Origin : Indonesia

Al Fikar Raihan, Universitas Mataram

Author Origin : Indonesia

Rian Akka Jaya Putra, Universitas Mataram

Author Origin : Indonesia

Maz Isa Ansyori Arsyatt, Universitas Mataram

Author Origin : Indonesia

Downloads

Download data is not yet available.

How to Cite

Kamila, A. S., Ginuluh, G. D., Syakir, S. A., Abida, A. N., Balqis, A. A., Karlina, F., … Arsyatt, M. I. A. (2024). Deep Vein Thrombosis (DVT): A Literature Review. Jurnal Biologi Tropis, 24(1b), 498–505. https://doi.org/10.29303/jbt.v24i1b.8008

Most read articles by the same author(s)

Similar Articles

1 2 3 4 5 6 7 8 9 10 > >> 

You may also start an advanced similarity search for this article.