Effectiveness of Non-SLS Shampoo Based on VCO and Tectona grandis Leaf Extract for Alopecia Treatment

Abstract

Hair loss is a common condition found in various groups. Various factors can cause hair loss, including genetic factors, hormonal imbalance, stress, nutritional deficiencies, and certain medical conditions. The type of disorder that occurs can be hair loss (effluvium) or hair loss disorders to baldness (alopecia). The study aims to determine the effectiveness of non-SLS shampoo preparations with a combination of teak leaf extract (Tectona grandis) and virgin coconut oil (Cocos nucifera) in overcoming hair loss and increasing hair growth rate. The shampoo preparation was tested on mice with 4 treatment groups consisting of 1 control group and 3 groups of mice that were given treatment (P1 containing 1,5% teak leaf extract and 0% VCO, P2 containing 2% teak leaf extract and 0,15% VCO, and P3 containing 2,5% teak leaf extract and 0,30% VCO). The trial on mice was conducted for 21 days and the calculation of the length of the mouse fur using a caliper was carried out periodically for 7 days. The results of study showed that the third formula showed an increase in the rate of hair growth. The effect of shampoo that showed most significant difference was P3 with 2,5% teak leaf extract and 0,30% coconut oil. Shampoo products containing teak leaf extract and coconut oil have been proven to have potential to increase rate of hair growth. This shampoo formula can also reduce hair loss supported by scientific journals reporting that teak leaf extract can inhibit work of steroid 5-α reductase (5SAR) and secretion of Interleukin-1 Beta (1L-1β), where both compounds have a negative impact on hair growth.