Systematic Review: Cytotoxicity Test of Bioactive Compounds of Asteraceae Family Plant Extracts on HeLa Cell Line

Windi Nofri Yanti; Mifta Hulrahma; Kharisma Annisa Aprilia; Amelia Roza; Kurniadi Ilham; Rita Maliza

doi:10.29303/jbt.v24i4.7007

Systematic Review: Cytotoxicity Test of Bioactive Compounds of Asteraceae Family Plant Extracts on HeLa Cell Line

Authors

Windi Nofri Yanti , Mifta Hulrahma , Kharisma Annisa Aprilia , Amelia Roza , Kurniadi Ilham , Rita Maliza

DOI:

10.29303/jbt.v24i4.7007

Published:

2024-10-07

Issue:

Vol. 24 No. 4 (2024): Oktober - Desember

Keywords:

Cell Line HeLa, Extract, In Vitro, MTT Assay

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Yanti, W. N., Hulrahma, M., Aprilia, K. A., Roza, A., Ilham, K., & Maliza, R. (2024). Systematic Review: Cytotoxicity Test of Bioactive Compounds of Asteraceae Family Plant Extracts on HeLa Cell Line . Jurnal Biologi Tropis, 24(4), 24–32. https://doi.org/10.29303/jbt.v24i4.7007

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Abstract

HeLa cancer cells are cervical cancer cells due to Human Papillomavirus (HPV 18) infection and thus have different properties from normal cervical cells. In recent decades, the number of plant species used in alternative medicine for cervical cancer-related purposes has increased. This systematic review aims to facilitate the review of the potential bioactive compounds of plant medicines and analyze how medicinal plants affect cancer cells. Scientific related questions, databases to be used, selection of keywords, inclusion and exclusion criteria, definition of results and conclusions of selected articles are all elements included in this research search strategy. Eight articles met the inclusion criteria and examined plant-derived compounds for their toxicity to HeLa cell lines. The bioactive compounds of this plant inhibit the growth of cancer cells.

References

Ahmed, S. I., Hayat, M. Q., Tahir, M., Mansoor, Q., Ismail, M., Keck, K., & Bates, R. B. (2016). Pharmacologically active flavonoids from the anticancer, antioxidant and antimicrobial extracts of Cassia angustifolia Vahl. BMC complementary and alternative medicine, 16, 1-9. https://doi.org/10.1186/s12906-016-1443-z

Amal, S., Gunarti, N. S., Soebakti, K. P., Mahdalena, D. G., Fadhillah, N. N., & Hidayah, H. (2021). Uji Aktivitas Antihiperurisemia Ekstrak Etanol beberapa Tumbuhan Famili Asteraceae. Majalah Farmasetika, 6, 32-41. https://doi.org/10.24198/mfarmasetika.v6i0.36673

Artun, T., Karagoz, A., Ozcan, G., Melikoglu, G., Anil, S., Kultur, S., & Sutlupinar, N. (2016). In vitro anticancer and cytotoxic activities of some plant extracts on HeLa and Vero cell lines. Journal of BU ON.: official journal of the Balkan Union of Oncology, 21(3), 720-725. https://doi.org/10.3390/proceedings1101019

Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians, 68(6), 394-424. https://doi.org/10.3322/caac.21492

Esmaeilbeig, M., Kouhpayeh, S. A., & Amirghofran, Z. (2015). An investigation of the growth inhibitory capacity of several medicinal plants from Iran on tumor cell lines. Iranian journal of cancer prevention, 8(5). https://doi.org/10.17795/ijcp-4032

Ferlay, J., Colombet, M., Soerjomataram, I., Parkin, D. M., Piñeros, M., Znaor, A., & Bray, F. (2021). Cancer statistics for the year 2020: An overview. International journal of cancer, 149(4), 778-789. https://doi.org/10.1002/ijc.33588

Guvensen, N. C., Keskin, D., Gunes, H., Oktay, M. K., & Yildirim, H. (2019). Antimicrobial property and antiproliferative activity of Centaurea babylonica (L.) L. on human carcinomas and cervical cancer cell lines. Annals of Agricultural and Environmental Medicine, 26(2). https://doi.org/10.26444/aaem/108563

Hussain, M., Raja, N. I., Mashwani, Z. U. R., Iqbal, M., Sabir, S., & Yasmeen, F. (2017). In vitro seed germination and biochemical profiling of Artemisia absinthium exposed to various metallic nanoparticles. 3 Biotech, 7, 1-8. https://doi.org/10.1007/s13205-017-0741-6

Jing, S., Zhang, X., & Yan, L. J. (2015). Antioxidant activity, antitumor effect, and antiaging property of proanthocyanidins extracted from Kunlun Chrysanthemum flowers. Oxidative Medicine and Cellular Longevity, 2015(1), 983484. https://doi.org/10.1155/2015/983484

Kalonio, D. E., Hendriani, R., & Barung, E. N. (2017). Aktivitas Antikanker Tanaman Genus Clerodendrum (Lamiaceae): Sebuah Kajian. Traditional Medicine Journal, 22(3), 182-189. https://doi.org/10.22146/mot.31554

Kowalczyk, T., Merecz-Sadowska, A., Rijo, P., Mori, M., Hatziantoniou, S., Gorski, K., ... & Sitarek, P. (2022). Hidden in plants—A review of the anticancer potential of the Solanaceae family in in vitro and in vivo studies. Cancers, 14(6), 1455. http://dx.doi.org/10.3390/cancers14061455

KÜLTÜR¹, Ş. Ü. K. R. A. N., Bona, M., & NATH, E. Ö. (2016). A new species of Centaurea (Asteraceae) from East Anatolia, Turkey. Phytotaxa, 247(1), 085-091. https://doi.org/10.11646/phytotaxa.247.1.6

Novalia, V. (2023). Kanker Serviks. GALENICAL: Jurnal Kedokteran Dan Kesehatan Mahasiswa Malikussaleh, 2(1), 45-56. https://doi.org/10.29103/jkkmm.v2i1.10134

Nugroho, A., Choi, J. S., & Park, H. J. (2016). Analysis of flavonoid composition of Korean herbs in the family of compositae and their utilization for health. Natural Product Sciences, 22(1), 1-12. https://doi.org/10.20307/nps.2016.22.1.1

Paputungan, W. A. (2017). Standardisasi parameter spesifik dan uji aktivitas antikanker terhadap sel kanker kolon (Widr) dari ekstrak etanol Lamun (Enhalus Acoroides). Pharmacon, 6(3). https://doi.org/10.35799/pha.6.2017.16883

Persia, F. A., Rinaldini, E., Carrión, A., Hapon, M. B., & Gamarra-Luques, C. (2017). Evaluation of cytotoxic and antitumoral properties of Tessaria absinthioides (Hook & Arn) DC," pájaro bobo", aqueous extract. MEDICINA (Buenos Aires), 77(4), 283-290. https://doi.org/10.3389/fphys.2021.662833

Renggana, H., Hadisaputri, Y. E., & Subarnas, A. (2019). Aktivitas Antikanker Famili Myrtaceae. Jurnal Ilmiah Farmako Bahari, 9(2), 23-32. http://dx.doi.org/10.52434/jfb.v9i2.506

Rodenak-Kladniew, B., Castro, M. A., Crespo, R., Galle, M., & de Bravo, M. G. (2020). Anti-cancer mechanisms of linalool and 1, 8-cineole in non-small cell lung cancer A549 cells. Heliyon, 6(12). https://doi.org/10.1016/j.heliyon.2020.e05639

Sartika, T. (2020). Analisis pelaksanaan skrining kanker serviks pada wanita usia subur. Jurnal'Aisyiyah Medika, 5(1). https://doi.org/10.36729/jam.v5i1.675

Sheashea, A. A., Ahmed, F. A., El Zayat, E., Ebeed, B. W., Elberry, M. H., Hassan, Z. K., & Hafez, M. M. (2024). In Vitro Antiviral and Anticancer Effects of Tanacetum sinaicum Essential Oil on Human Cervical and Breast Cancer. Asian Pacific Journal of Cancer Prevention: APJCP, 25(4), 1457. https://doi.org/10.31557/APJCP.2024.25.4.1457

Shree, T. J., Poompavai, S., Begum, S. M. F. M., Gowrisree, V., Hemalatha, S., Sieni, E., & Sundararajan, R. (2019). Cancer-fighting phytochemicals: another look. J. Nanomed. Biother. Discov, 8, 162. http://dx.doi.org/10.13057/biodiv/d220735

Tiwary, B. K., Bihani, S., Kumar, A., Chakraborty, R., & Ghosh, R. (2015). The in vitro cytotoxic activity of ethno-pharmacological important plants of Darjeeling district of West Bengal against different human cancer cell lines. BMC complementary and alternative medicine, 15, 1-10. https://doi.org/10.1186/s12906-015-0543-5

Wardhani, M. Y., Fitrianingsih, S. P., & Suwendar, S. (2021). Studi Literatur Aktivitas Antikanker Famili Euphorbiaceae. Prosiding Farmasi, 175-179. http://dx.doi.org/10.29313/.v0i0.28822

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Systematic Review: Cytotoxicity Test of Bioactive Compounds of Asteraceae Family Plant Extracts on HeLa Cell Line

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