Literature Review: The Chemical Composition and Pharmacological Activities of Nannochloropsis sp

Ryhadatul Ulfiyah; Zerati Hijriadina; Baiq Khaeratinnisa Oktari; Diah Hikmatin Anjanisa; Reivirly Khairadaty Magvirahandini; Ulfatul Mutthoimah; Anggit Listyacahyani

doi:10.29303/jbt.v25i3.8593

Literature Review: The Chemical Composition and Pharmacological Activities of Nannochloropsis sp

Authors

Ryhadatul Ulfiyah , Zerati Hijriadina , Baiq Khaeratinnisa Oktari , Diah Hikmatin Anjanisa , Reivirly Khairadaty Magvirahandini , Ulfatul Mutthoimah , Anggit Listyacahyani

DOI:

10.29303/jbt.v25i3.8593

Published:

2025-07-14

Issue:

Vol. 25 No. 3 (2025): Juli-September

Keywords:

Bioactive compounds, Nannochloropsis sp, microalgae, pharmacological activities.

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Ulfiyah, R., Hijriadina, Z., Oktari, B. K., Anjanisa, D. H., Magvirahandini, R. K., Mutthoimah, U., & Listyacahyani, A. (2025). Literature Review: The Chemical Composition and Pharmacological Activities of Nannochloropsis sp. Jurnal Biologi Tropis, 25(3), 2809–2812. https://doi.org/10.29303/jbt.v25i3.8593

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Abstract

The microalga Nannochloropsis sp. is a potential bioactive source with various applications in the pharmaceutical and health industries. This study aims to identify its chemical composition and evaluate its pharmacological activities, including antioxidant, antidiabetic, antibacterial, antihyperlipidemic, and cytotoxic properties. The method involves a literature review of relevant and recent scientific articles using specific keywords. The results indicate that Nannochloropsis sp. is rich in bioactive compounds, such as unsaturated fatty acids, flavonoids, and phenolics, which contribute to its biological activities. This microalga has been shown to effectively inhibit pathogenic bacterial growth, reduce blood sugar, cholesterol, and lipid levels, and possess potential anticancer activity. The study concludes that Nannochloropsis sp. has promising prospects as a natural raw material source for modern drug development. Further research is recommended to explore the mechanisms of its bioactive compounds and to develop formulations for products based on this microalga.

References

Bendimerad-Benmokhtar, S., Bouanane, S., Merzouk, H., Baba Ahmed, F. Z., & Bendaoud, A. (2019). Effects of Nannochloropsis fed on serum and tissue lipids metabolism in obese offspring of overfed dams. Current Nutrition & Food Science, 15(1), 72-86. 10.2174/157340131401180115121643

Borowitzka, M. A. (1995). Microalgae as sources of pharmaceuticals and other biologically active compounds. Journal of applied phycology, 7(1), 3-15.

Cahyaningsih, S. (2013). Produksi Pakan Alami. Balai Budidaya Air Payau Situbondo. Direktorat Jenderal Perikanan Budidaya Laut. Departemen Kelautan Dan Perikanan.

Deepa, P. K., Subramanian, A., & Manjusha, W. A. (2022). Phytochemical Screening and Evaluation of Antidiabetic Activity of the Marine Microalgae: Nannochloropsis Sp..(2020). Int. J. Life Sci. Pharma Res, 10(4), L36-40. https://doi.org/10.22376/ijpbs/lpr.2020.10.4.l36-40.

Ferdous, U. T., & Yusof, Z. N. B. (2021). Medicinal prospects of antioxidants from algal sources in cancer therapy. Frontiers in Pharmacology, 12, 593116. 10.3389/fphar.2021.593116.

Fithriani, D., Yunita, E., Kurniasari, A., & Martha, F. (2019). Pengaruh Pemberian Nannochloropsis oculata terhadap Kadar Total Kolesterol dan Berat Badan Tikus Sprague Dawley yang Mengalami Hypercholesterolemia. Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan, 14(2), 107-116.

Gnanakani, P., Santhanam, P., Kumar, K., & Dhanaraju, M. (2019). Chemical composition, antioxidant, and cytotoxic potential of Nannochloropsis species extracts. Journal of Natural Science, Biology and Medicine, 10(2), 167-177.

Verdugo-González, L., Acosta-Cárdenas, A., Zapata-Zapata, A. D., Cadena-Chamorro, E. M., & Pulido-Muñoz, S. A. (2019). Antimicrobial potential of a hydrolyzed protein extract of the microalgae Nannochloropsis sp. Dyna, 86(211), 192-198. https://doi.org/10.15446/dyna.v86n211.78865.

Kawaroe M., Prartono, T., Sunuddin A., Sari D.W., Augustine D. (2010). Mikroalga: Potensi dan Pemanfaatannya untuk Produksi Bio Bahan Bakar. IPB Press. Bogor.

Muhammad, R. (2023). Pengaruh Pemberian Pupuk Organik Cair (POC) Biourin Kambing Terhadap Kepadatan Sel Dan Laju Pertumbuhan Nannochloropsis sp (Doctoral dissertation, Universitas Malikussaleh).

Nacer W., Baba Ahmed FZ, Merzouk H., Benyagoub O., Bouanane S. (2020). Evaluasi efek antiinflamasi dan antioksidan dari mikroalga Nannochloropsis gaditana pada tikus diabetes yang diinduksi streptozotocin. J. Diabetes Metab. Disord. 10.1007/s40200-020-00681-3.

Nasirian, F., Sarir, H., & Moradi-Kor, N. (2019). Antihyperglycemic and antihyperlipidemic activities of Nannochloropsis oculata microalgae in streptozotocin-induced diabetic rats. Biomolecular concepts, 10(1), 37-43. https://doi.org/10.1515/bmc-2019-0004.

Rajendran N., Karpanai, S.B., Sobana, P.P.V ., Logeswari, Katrhiresan, E., Tamilselvi, A., John, V .S. (2014). Phytochemicals, Antimicrobial and Screening from Antioxidant Five Marine Microalgae. Journal of Chemical and Pharmaceutical 2:78-85.

Surendhiran, D., Vijay, M., Sirajunnisa, A. R., Subramaniyan, T., Subramaniyan, A. S., & Tamilselvam, K. (2014). A green synthesis of antimicrobial compounds from marine microalgae Nannochloropsis oculata. Journal of Coastal Life Medicine, 2(11), 859-863.

Agustini, N. W. S. (2014). Potensi asam lemak dari mikroalga Nannochloropsis sp sebagai antioksidan dan antibakteri. In Proceeding Biology Education Conference: Biology, Science, Enviromental, and Learning (Vol. 11, No. 1, pp. 149-155).

Yanuhar, U. (2016). Mikroalga laut Nannochloropsis oculata. Universitas Brawijaya Press.

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Literature Review: The Chemical Composition and Pharmacological Activities of Nannochloropsis sp

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