The Relationship Between Age and Comorbidities (Type 2 Diabetes Mellitus and Hypertension) and Hearing Loss in Women Over 40 Years of Age
DOI:
10.29303/jbt.v25i3.9999Published:
2025-08-25Downloads
Abstract
Hearing loss is a public health problem that increases with age and can be exacerbated by comorbidities such as type 2 diabetes mellitus (DM) and hypertension. This study analyzed the relationship between age and comorbidities (DM type 2 and hypertension) on hearing loss in women over 40 years old. A cross-sectional analytical study of 34 women over 40 years old in Kotamatsum IV Village, Medan. Hearing examinations were performed using pure tone audiometry and otoacoustic emission (OAE). Statistical analysis was performed using the Chi-Square, Mann-Whitney, and Kruskal-Wallis tests. There was a significant relationship between age and the degree of hearing loss (p=0.047), with the majority of subjects aged >50 years experiencing mild deafness. However, no significant relationship was found between comorbidities of type 2 DM and/or hypertension on the degree, type of hearing loss, or OAE results (p>0.05). Age was significantly associated with the degree of hearing loss, while type 2 DM and hypertension did not show a significant relationship. Further research is needed considering disease duration and treatment adherence to further understand the contribution of comorbidities to hearing loss.
Keywords:
Audiometry Age Hearing loss Hypertension Type 2 DM OAEReferences
Al- Al-Rubeaan, K., AlMomani, M., AlGethami, A. K., Darandari, J., Alsalhi, A., AlNaqeeb, D., ... & Youssef, A. M. (2021). Hearing loss among patients with type 2 diabetes mellitus: a cross-sectional study. Annals of Saudi Medicine, 41(3), 10.5144/0256-4947.2021.171
Bener A, Al-Hamaq AOAA, Abdulhadi K, Salahaldin AH, Gansan L. Interaction between diabetes mellitus and hypertension on risk of hearing loss in highly endogamous population. Diabetes Metab Syndr Clin Res Rev [Internet]. 2017;11:S45–51. http://dx.doi.org/10.1016/j.dsx.2016.09.004
Bowl, M. R., & Dawson, S. J. (2019). Age-related hearing loss. Cold Spring Harbor perspectives in medicine, 9(8), a033217.
Chanifah, S. (2015). Hubungan Hipertensi Terhadap Gangguan Pendengaran Sensorineural Studi Observasional Analitik di Rumah Sakit Islam Sultan Agung Semarang (Doctoral dissertation, Fakultas Kedokteran UNISSULA).
Chen, H. C., Chung, C. H., Lu, C. H., & Chien, W. C. (2019). Metformin decreases the risk of sudden sensorineural hearing loss in patients with diabetes mellitus: A 14-year follow-up study. Diabetes and Vascular Disease Research, 16(4), 324-327. 10.1177/1479164119826292
Eggermont, J. J. (2017). Epidemiology and genetics of hearing loss and tinnitus. Hearing Loss, 209-234. 10.1016/B978-0-12-805398-0.00007-4
Gong, R., Hu, X., Gong, C., Long, M., Han, R., Zhou, L., ... & Zheng, X. (2018). Hearing loss prevalence and risk factors among older adults in China. International journal of audiology, 57(5), 354-359. 10.1080/14992027.2017.1423404
Guthrie, D. M., Davidson, J. G., Williams, N., Campos, J., Hunter, K., Mick, P., ... & Wittich, W. (2018). Combined impairments in vision, hearing and cognition are associated with greater levels of functional and communication difficulties than cognitive impairment alone: Analysis of interRAI data for home care and long-term care recipients in Ontario. PloS one, 13(2), e0192971. 10.1371/journal.pone.0192971
Haile, L. M., Kamenov, K., Briant, P. S., Orji, A. U., Steinmetz, J. D., Abdoli, A., ... & Rana, J. (2021). Hearing loss prevalence and years lived with disability, 1990–2019: findings from the Global Burden of Disease Study 2019. The Lancet, 397(10278), 996-1009. 10.1016/S0140-6736(21)00516-X
Haile, L. M., Orji, A. U., Reavis, K. M., Briant, P. S., Lucas, K. M., Alahdab, F., ... & GBD 2019 USA Hearing Loss Collaborators. (2024). Hearing loss prevalence, years lived with disability, and hearing aid use in the United States from 1990 to 2019: findings from the Global Burden of Disease Study. Ear and hearing, 45(1), 257-267. 10.1097/AUD.0000000000001420
Hara, K., Okada, M., Takagi, D., Tanaka, K., Senba, H., Teraoka, M., ... & Miyake, Y. (2020). Association between hypertension, dyslipidemia, and diabetes and prevalence of hearing impairment in Japan. Hypertension Research, 43(9), 963-968. 10.1038/s41440-020-0444-y
Henshaw, H., Calvert, S., Heffernan, E., Broome, E. E., Burgon, C., Dening, T., & Fackrell, K. (2023). New horizons in hearing conditions. Age and Ageing, 52(8), afad150. 10.1093/ageing/afad150
Lawrence, B. J., Jayakody, D. M., Bennett, R. J., Eikelboom, R. H., Gasson, N., & Friedland, P. L. (2020). Hearing loss and depression in older adults: a systematic review and meta-analysis. The Gerontologist, 60(3), e137-e154. 10.1093/geront/gnz009
Lin, B. M., Curhan, S. G., Wang, M., Eavey, R., Stankovic, K. M., & Curhan, G. C. (2016). Hypertension, diuretic use, and risk of hearing loss. The American journal of medicine, 129(4), 416-422. 10.1016/j.amjmed.2015.11.014
Lin, F. R., Thorpe, R., Gordon-Salant, S., & Ferrucci, L. (2011). Hearing loss prevalence and risk factors among older adults in the United States. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences, 66(5), 582-590. 10.1093/gerona/glr002
Löhler, J., Cebulla, M., Shehata-Dieler, W., Volkenstein, S., Völter, C., & Walther, L. E. (2019). Schwerhörigkeit im Alter–Erkennung, Behandlung und assoziierte Risiken. Dtsch Arztebl Int, 116(17), 301-310. 10.3238/arztebl.2019.0301
Meneses-Barriviera, C. L., Bazoni, J. A., Doi, M. Y., & Marchiori, L. L. D. M. (2018). Probable association of hearing loss, hypertension and diabetes mellitus in the elderly. International archives of otorhinolaryngology, 22(04), 337-341. 10.1055/s-0037-1606644
Nawaz, M. U., Vinayak, S., Rivera, E., Elahi, K., Tahir, H., Ahuja, V., ... & Ahar, W. (2021). Association between hypertension and hearing loss. Cureus, 13(9). 10.7759/cureus.18025
Reed, N. S., Huddle, M. G., Betz, J., Power, M. C., Pankow, J. S., Gottesman, R., ... & Deal, J. A. (2019). Association of midlife hypertension with late-life hearing loss. Otolaryngology–Head and Neck Surgery, 161(6), 996-1003. 10.1177/0194599819868145
Rigters, S. C., van der Schroeff, M. P., Papageorgiou, G., Baatenburg de Jong, R. J., & Goedegebure, A. (2019). Progression of hearing loss in the aging population: repeated auditory measurements in the Rotterdam study. Audiology and Neurotology, 23(5), 290-297. 10.1177/0194599819868145
Samocha-Bonet, D., Wu, B., & Ryugo, D. K. (2021). Diabetes mellitus and hearing loss: a review. Ageing Research Reviews, 71, 101423. 10.1016/j.arr.2021.101423
Sharma, R. K., Lalwani, A. K., & Golub, J. S. (2020). Prevalence and severity of hearing loss in the older old population. JAMA Otolaryngology–Head & Neck Surgery, 146(8), 762-763. 10.1001/jamaoto.2020.0900
Shuster, B. Z., Depireux, D. A., Mong, J. A., & Hertzano, R. (2019). Sex differences in hearing: Probing the role of estrogen signaling. The Journal of the Acoustical Society of America, 145(6), 3656-3663. 10.1121/1.5111870
Soiza, R. L., Donaldson, A. I. C., & Myint, P. K. (2018). Vaccine against arteriosclerosis: an update. Ther Adv Vaccines, 9(6), 259-61. https://doi.org/10.1177/2042098618769568
Wang, C. T., Huang, T. W., Kuo, S. W., & Cheng, P. W. (2009). Correlation between audiovestibular function tests and hearing outcomes in severe to profound sudden sensorineural hearing loss. Ear and hearing, 30(1), 110-114. 10.1097/AUD.0b013e318192655e
World Health Organization. Global Estimates on Prevalence of Hearing Loss Mortality and Burden of Diseases and Prevention of Blindness and Deafness. 2012.
World Health Organization. World Report On Hearing [Internet]. Human Rights Watch. 2021. 1–272 p. Available from: https://www.who.int/publications/i/item/world-report-on-hearing
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