Potential Antioxidant Activity of Tropical Brown Macroalgae Turbinaria Ethanol Extract from Kabung Island West Kalimantan
Authors
Mega Sari Juane Sofiana , Apriansyah Apriansyah , Bambang Kurniadi , Warsidah Warsidah , Rita Kurnia Apindiati , Ikha Safitri , Syarif Irwan NurdiansyahDOI:
10.29303/jbt.v22i4.4385Published:
2022-12-09Issue:
Vol. 22 No. 4 (2022): October - DecemberKeywords:
antioxidant, Turbinaria, Ethanol, Kabung Island, West KalimantanArticles
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Abstract
Naturally, the human body has tolerance to free radical attacks. However, the natural antioxidant ability will decrease when exposure to free radicals from within and outside the body occurs intensively. Antioxidants play potential preventive role to protect the body from damage associated with oxidative stress by free radicals. One of the potential marine resources used as an antioxidant is macroalgae. Turbinaria is widely distributed in tropical waters of Indonesia, including West Kalimantan. This genus produces secondary metabolites with several biological activities. This genus abundantly grows in Kabung Island. However, it has not been used by the local community, even tends to be considered as a weed that disturbs others marine biota. This study aimed to evaluate the potential antioxidant activity of tropical brown macroalgae Turbinaria ethanol extract from Kabung Island, West Kalimantan. antioxidant activity was evaluated using the DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical scavenger method with UV-vis spectrophotometer. The result showed that the ethanolic extract had a high of potential antioxidant activity which IC50 was 87.31 mg/L and it was classified into strong antioxidant potential.
References
Anggadiredja, J.T., Zatnika, A., Purwoto, H. & Istini, S. (2008). Rumput Laut, Pembudidayaan, Pengolahan, dan Pemasaran Komoditas Perikanan Potensial. Jakarta: Penebar Swadaya. 147 hlm.
Banerjee, A., Dasgupta, N. & De, B. (2005). In vitro study of antioxidant activity of Syzygium cumini fruit. Food Chemistry, 90(4): 727-733. DOI:10.1016/j.foodchem.2004.04.033
Bhaigyabati, T., Kirithika, T., Shiny, K. & Usha, K. (2011). Phytochemical screening and antioxidant activity of various extracts of Sargassum muticum. IJPRD.
Biris-Dorhoi, E-S., Michiu, D., Pop, C.R., Rotar, A.M., Tofana, M., Pop, O.L., Socaci, S.A. & Farcas, A.C. (2020). Macroalgae - A Sustainable Source of Chemical Compounds with Biological Activities. Nutrients, 12: 3085. doi:10.3390/nu12103085
Chakraborty, K., Joseph, D. & Praveen, N.K. (2015). Antioxidant activities and phenolic contents of three red seaweeds (Division: Rhodophyta) harvested from the Gulf of Mannar of Peninsular India. J. Food Sci. Technol., 52: 1924-1935. doi: 10.1007/s13197-013-1189-2
Chakraborty, K. & Joseph, D. (2016). Antioxidant potential and phenolic compounds of brown seaweeds Turbinaria conoides and Turbinaria ornata (class: Phaeophyceae). Journal of Aquatic Food Product Technology, 25(8): 1249-1265. doi.org/10.1080/10498850.2015.1054540
Chale-Dzul, J., Moo-Puc, R., Robledo, D. & Freile-Pelegrin, F. (2014). Hepatoprotective effect of the fucoidan from the brown seaweed Turbinaria tricostata. Journal of Applied Phycology, 26(2): 1009-1017. DOI:10.1007/s10811-014-0429-9
Donapaneedi, S.N., Suresh, K.A., Chakraborty, K. & Valluru, L. (2018). Invitro Antiproliferative Effect of Marine Macroalgae on Different Human Cancer Cell Lines. International Journal of Pharmaceutics & Drug Analysis, 6(2): 342-351.
Eldrin, D.L.R., Arguelles, E.D.L.R. & Sapin, A.B. (2020). Bioprospecting of Turbinaria ornata (Fucales, Phaeophyceae) for Cosmetic Application: Antioxidant, Tyrosinase Inhibition and Antibacterial Activities. Journal of the International Society for Southeast Asian Agricultural Sciences, 26(2): 30-41.
Guiry, M.D. & Guiry, G.M. (2018). Algabase. Galway, World-wide Electronic Publication.
Handayani, T. (2018). Mengenal Makroalga Turbinaria dan Pemanfaatannya. Oseana, 43(4): 28-39. DOI:10.14203/oseana.2018.Vol.43No.4.5
Hermund, D.B., Karadag, A., Andersen, U., Jonsdottir, R., Kristinsson, H.G., Alasarval, C. & Jacobsen, C. (2016). Oxidative stability of granola bars enriched with multilayered fish oil emulsion in the presence of novel brown seaweed base antioxidants. Journal of Agricultural and Food Chemistry, 64(44): 8359-8368. DOI: 10.1021/acs.jafc.6b03454
Husni, A. & Budhiyanti, S.A. (2021). Rumput Laut sebagai Sumber Pangan, Kesehatan dan Kosmetik. Yogyakarta: UGM Press. 158 hlm.
Islami, F., Ridlo, A. & Pramesti, R. (2014). Aktivitas Antioksidan Ekstrak Rumput Laut Turbinaria decurrens Bory De Saint-Vincent Dari Pantai Krakal, Gunung Kidul, Yogyakarta. Journal of Marine Research, 3(4): 605-616. doi.org/10.14710/jmr.v3i4. 11422
John, D.M. & Al-Thani, R.F. (2014). Benthic marine algae of the Arabian Gulf: a critical review and analysis of distribution and diversity patterns. Nova Hedwigia, 98(3-4): 341-392. DOI:10.1127/0029-5035/2014/ 0156
Kadi, A. (2006). Beberapa Catatan Kehadiran Marga Sargassum di Perairan Indonesia. Jurnal Oseana, 4, 19-29.
Kim, E., Cui, J., Kang, I., Zhang, G. & Lee, Y. (2021). Potential Antidiabetic Effects of Seaweed Extracts by upregulating Glucose Utilization and Alleviating Inflammation in C2C12 Myotubes. Int. J. Environ. Res. Public Health, 18: 1367. DOI: 10.3390/ijerph18031367
Kumar, Y., Tarafdar, A. & Badgujar, P.C. (2021). Seaweed as a Source of Natural Antioxidants: Therapeutic Activity and Food Applications. Journal of Food Quality, 1-17. https://doi.org/10.1155/2021/5753391.
Kumaran, A. & Karunakaran, R. (2006). Antioxidant and free radical scavenging activity of an aqueous extract of Coleus Aromaticus. Food Chemistry, 97(1): 109-114. DOI:10.1016/j.foodchem.2005.03.032
Leandro, A., Pereira, L. & Gonçalves, A.M.M. (2020).Diverse Applications of Marine Macroalgae. Mar. Drugs., 18: 17. DOI: 10.3390/md18010017
Lee, H., Selvaraj, B. & Lee, J.W. (2021). Anticancer Effects of Seaweed-Derived Bioactive Compounds. Appl. Sci., 11: 11261. doi.org/10.3390/app112311261
Lomartire, S. & Gonçalves, A.M.M. (2022). Antiviral Activity and Mechanisms of Seaweeds Bioactive Compounds on Enveloped Viruses - A Review. Mar. Drugs., 20: 385. DOI: 10.3390/md20060385
Luthfiyana, N., Nurjanah, Nurilmala, M., Anwar, E. & Hidayat, T. (2016). Rasio Bubur Rumput Laut Eucheuma cottonii dan Sargassum sp. sebagai Formula Krim Tabir Surya. JPHPI, 19(3): 183-195. DOI:10.17844/jphpi.v19i3.14476
Maharani, A.A., Husni, A. & Ekantari, N. (2017). Karakteristik Natrium Alginat Rumput Laut Cokelat Sargassum fluitans dengan Metode Ekstraksi yang Berbeda. Jurnal Pengolahan Hasil Perikanan Indonesia, 20(3):478-487.
Miranda-Delgado, A., Montoya, M.J., Paz-Araos, M., Mellado, M., Villena, J., Arancibia, P., Madrid, A. & Jara-Gutiérrez, C. (2018). Antioxidant and anti-cancer activities of brown and red seaweed extracts from Chilean coasts. Lat. Am. J. Aquat. Res., 46(2): 301-313. doi.org/10.3856/vol46
Molyneux, P. (2004). The Use of Stable Free Radical Diphenylpicryl-hydrazyl (DPPH) for Estimating Antioxidant Activity. J. Sci. Technol., 26(2): 211-219.
Namvar, F., Mohamad, R., Baharara, J., Zafar-Balanejad, S., Fargahi, F. & Rahman, H.S. (2013). Antioxidant, Antiproliferative, and Antiangiogenesis Effects of Polyphenol-Rich Seaweed (Sargassum muticum). BioMed Research International, 1-9. DOI: 10.1155/2013/604787
Niamaimandi, N. (2006). Bio-dynamics and life cycle of shrimp (Penaeus semisulcatus De Haan), in Bushehr coastal waters of the Persian Gulf. Universiti Putra Malaysia. [Thesis].
Nurunnisa, A.T. (2021). Bioaktivitas dan Identifikasi Golongan Senyawa Aktif Ekstrak Rumput Laut Turbinaria conoides dari Pulau Samalona. Program Studi Pemanfaatan Sumberdaya Perikanan, Fakultas Ilmu Kelautan dan Perikanan, Universitas Hasanuddin. [Skripsi].
Ozsoy, N., Can, A., Yanardag, R. & Akev, N. (2008). Antioxidant activity of Smilax excelsa L. leaf extracts. Food Chemistry, 110(3): 571-583. doi.org/10.1016/j.foodchem.2008.02.037
Pliego-Cortés, H., Hardouin, K., Bedoux, G., Marty, C., Cérantola, S., Freile-Pelegrín, Y., Robledo, D. & Bourgougnon, N. (2022). Sulfated Polysaccharides from Seaweed Strandings as Renewable Source for Potential Antivirals against Herpes simplex Virus 1. Mar. Drugs., 20: 116. DOI: 10.3390/md20020116
Prasedya, E.S., Hamdin, C.D., Riandinata, S.K., Rosidah, S., Susumu, Y., Miyake, M., Kobayashi, D., Hazama, A. & Sunarpi, H. (2018). Antiproliferative and immunomodulatory activity of edible seaweed Gelidium latifolium. Sci. Pharm., 1-14.
Reyes, M.E., Riquelme, I., Salvo, T., Zanella, L., Letelier, P. & Brebi, P. (2020). Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance. Mar. Drugs., 18: 232. doi: 10.3390/md18050232
Rushdi, M.I., Abdel-Rahman, I.A.M., Saber, H., Attia, Z.E., Abdelraheem, W.M., Madkour, H.A. & Abdelmohsen, U.R. (2020). The genus Turbinaria: chemical and pharmacological diversity. Natural Product Research, 1-19. doi.org/10.1080/14786419.2020.1731741
Safitri, I., Warsidah, Sofiana, M.S.J., Kushadiwijayanto, A.A. & Sumarni, T.N. (2021). Total Phenolic Content, Antioxidant and Antibacterial Activities of Sargassum polycystum of Ethanol Extract from Waters of Kabung Island. BERKALA SAINSTEK, 9(3): 139-145. doi.org/10.19184/bst.v9i3.27199
Sari, D.M., Anwar, E., Nurjanah, & Arifianti, A.E. (2019). Antioxidant and Tyrosinase Inhibitor Activities of Ethanol Extracts of Brown Seaweed (Turbinaria conoides) as Lightening Ingredient. Pharmacogn J., 11(1): 379-382. DOI:10.5530/pj.2019.11.58
Sofiana, M.S.J., Safitri, I., Warsidah, Helena, S. & Nurdiansyah, S.I. (2021). Antioxidant and Anti-Inflammatory Activities from Ethanol Extract of Eucheuma cottonii from Lemukutan Island Waters West Kalimantan. Saintek Perikanan: Indonesian Journal of Fisheries Science and Technology, 17(4): 247-25. DOI: https://doi.org/10.14710/ijfst.17.4.247-253
Sofiana, M.S.J., Nurrahman, Y.A., Warsidah, Minsas, S., Yuliono, A., Safitri, I., Helena, S. & Risko. (2022). Community Structure of Macroalgae in Lemukutan Island Waters, West Kalimantan. Jurnal Ilmu Kelautan SPERMONDE, 8(1): 1-8. doi.org/10.20956/jiks.v8i1.17914
Stranska-Zachariasova, M., Kurniatanty, I., Gbelcova, H., Jiru, M., Rubert, J., Nindhia, T.G.T., D’Acunto, C.W., Sumarsono, S.H., Tan, M.I., Hajslova, J. & Ruml, T. (2017). Bioprospecting of Turbinaria Macroalgae as a Potential Source ofHealth Protective Compounds. Chem. Biodiversity, 14: e1600192. doi.org/10.1002/cbdv.201600192
Sudhakar, K., Mamat, R., Samykano, M., Azmi, W.H., Ishak, W.F.W. & Yusaf, T. (2018). An overview of marine macroalgae as bioresource. Renewable and Sustainable Energy Reviews, 91: 165-179. doi.org/10.1016/j.rser.2018.03.100
Sumarni, T.N., Warsidah, Safitri, I., Kushadiwijayanto, A.A. & Sofiana, M.S.J. (2022). Analisis Kandungan Proksimat dan Mineral Zink dari Sargassum sp. Asal Perairan Pulau Kabung. Oseanologia, 1(1): 24-27. DOI: http://dx.doi.org/10.26418/jose.v1i1.53467
Pereira, L. (2018). Seaweeds as Source of Bioactive Substances and Skin Care Therapy-Cosmeceuticals, Algotheraphy, and Thalassotherapy. Cosmetics, 5: 68. doi.org/10.3390/cosmetics5040068
Qurniasih, I., Safitri, I., Aritonang, A.B. & Helena, S. (2022). Kandungan Total Fenol dalam Ekstrak Metanol dan Etil Asetat Caulerpa racemosa. Indo. J. Pure App. Chem., 5 (2): 96-104. doi.org/10.26418/indonesian.v5i2.49068
Warsidah, Safitri, I., Sofiana, M.S.J. & Helena, S. (2022). Antibacterial Activity from Ethanol and Ethyl Acetate Extracts of Padina pavonica Hauck from Kabung Island Against Escherichia coli. Saintek Perikanan: Indonesian Journal of Fisheries Science and Technology, 18(1): 1-6. DOI: https://doi.org/10.14710/ijfst.18.1.1-6
Yanuarti, R., Nurjanah, Anwar, E. & Hidayat, T. (2017). Profil fenolik dan aktivitas antioksidan dari ekstrak rumput laut Turbinaria conoides dan Eucheuma cottonii. Jurnal Pengolahan Hasil Perikanan Indonesia, 20(2): 230-237. DOI:10.17844/jphpi.v20i2.17503
Young, I.S. & Woodside, J.V. (2001). Antioxidants in health and disease. J. Clin. Pathol., 54: 176–86. DOI: 10.1136/jcp.54.3.176
Zou, Y., Lu, Y., Wei, D. (2004). Antioxidant Activity of Flavonoid Rich Extract of Hypericum perforatum L. in Vitro. J. Agric. Food. Chem., 52: 5032-5039. DOI: 10.1021/jf049571r
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