Antitumor from Several Plant Compounds Against Hepatocellular Carcinoma Cell Line Hep3B: Mini Systematic Review

Wardatul Aini; Azizah Amatu Zikrah; Sutri Wulansari Safril; Zozy Aneloi  Noni; Rita Maliza

doi:10.29303/jbt.v23i4.5528

Antitumor from Several Plant Compounds Against Hepatocellular Carcinoma Cell Line Hep3B: Mini Systematic Review

Authors

Wardatul Aini , Azizah Amatu Zikrah , Sutri Wulansari Safril , Zozy Aneloi Noni , Rita Maliza

DOI:

10.29303/jbt.v23i4.5528

Published:

2023-10-04

Issue:

Vol. 23 No. 4 (2023): October - December

Keywords:

Antitumor, hepatocellular carcinoma, Hep3B.

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Aini, W., Zikrah, A. A., Safril, S. W., Noni, Z. A. ., & Maliza, R. (2023). Antitumor from Several Plant Compounds Against Hepatocellular Carcinoma Cell Line Hep3B: Mini Systematic Review. Jurnal Biologi Tropis, 23(4), 449–457. https://doi.org/10.29303/jbt.v23i4.5528

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Abstract

Liver cancer is a global health challenge, with more than one million cases expected by 2025. Hepatocellular carcinoma (HCC) is the most common form of liver cancer and accounts for approximately 90% of cases. Nature provides a large source of natural medicines and compounds, one of which is plants. So, this article is made to contain information on the potential of several plants as antitumor agents. The method of preparing articles through literature review studies that collect articles from various sources such as ScienceDirect, google scholar, PubMed and others in the range of 2013 to 2023. There are ten plant bioactive compounds that have been tested in vitro on Hep3B cell lines to see their toxicity. These plant bioactive compounds play an important role in the proliferation phase, cell cycle, and cell apoptosis in liver cancer and have potential as antitumor.

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Author Biographies

Zozy Aneloi Noni

Departemen Biologi, Fakultas Matematika dan Ilmu Pengetahuan Andalas, Universitas Andalas, Indonesia

Rita Maliza

Departemen Biologi, Fakultas Matematika dan Ilmu Pengetahuan Andalas, Universitas Andalas, Indonesia

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Antitumor from Several Plant Compounds Against Hepatocellular Carcinoma Cell Line Hep3B: Mini Systematic Review

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Rita Maliza

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