Necrotizing Enterocolitis: Synbiotics, Probiotics, and Prebiotics Prevention
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Zirly Vera Aziri , Carolina Janicca Winda ManafeDOI:
10.29303/jbt.v24i4.7490Published:
2024-10-08Issue:
Vol. 24 No. 4 (2024): Oktober - DesemberKeywords:
Necrotizing enterocolitis, synbiotics, probiotics, prebiotics.Articles
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Abstract
Necrotizing Enterocolitis (NEC) or intestinal inflammation is a gastrointestinal disease that is the leading cause of death among infants. NEC is often diagnosed late due to its non-specific signs and symptoms, resulting in increased mortality and morbidity. The purpose of this paper is to explain the mechanisms of how synbiotics, probiotics, and prebiotics contribute to the prevention of NEC. Several randomized trials and observational studies have identified various factors associated with NEC. However, the causality of many of these factors remains unclear and may involve different etiological mechanisms. Prevention of NEC can be achieved through the administration of synbiotics, probiotics, and prebiotics. According to previous research, the administration of synbiotics, probiotics, and prebiotics has significant potential and benefits in preventing NEC. The data sources were obtained by conducting an online search through library databases, including PubMed, ProQuest, ScienceDirect, MDPI, and Google Scholar. According to previous research, the administration of synbiotics, probiotics, and prebiotics has significant potential and benefits in preventing NEC. This paper summarizes the current etiology, risk factors and synbiotics, probiotics, and prebiotics Prevention of Necrotizing Enterocolitis.
References
Alganabi, M., Lee, C., Bindi, E., Li, B., & Pierro, A. (2019) ‘Recent advances in understanding necrotizing enterocolitis [version 1; referees: 2 approved]’, F1000Research. F1000 Research Ltd. Available at: https://doi.org/10.12688/f1000research.17228.1.
Bazacliu, C. and Neu, J. (2019) ‘Necrotizing Enterocolitis: Long Term Complications’, Current Pediatric Reviews, 15(2), pp. 115–124. Available at: https://doi.org/10.2174/1573396315666190312093119.
Beghetti, I., Panizza, D., Lenzi, J., Gori, D., Martini, S., Corvaglia, L., & Aceti, A. (2021) ‘Probiotics for preventing necrotizing enterocolitis in preterm infants: A network meta-analysis’, Nutrients. MDPI AG, pp. 1–14. Available at: https://doi.org/10.3390/nu13010192.
Bellodas Sanchez, J. and Kadrofske, M. (2019) ‘Necrotizing enterocolitis’, Neurogastroenterology and Motility, 31(3). Available at: https://doi.org/10.1111/nmo.13569.
De Fazio, L., Beghetti, I., Bertuccio, S.N., Marsico, C., Martini, S., Masetti, R., Pession, A., Corvaglia, L., & Aceti, A. (2021) ‘Necrotizing enterocolitis: Overview on in vitro models’, International Journal of Molecular Sciences, 22(13). Available at: https://doi.org/10.3390/ijms22136761.
De Kroon, R. R., de Baat, T., Senger, S., & van Weissenbruch, M. M. (2022). Amniotic fluid: a perspective on promising advances in the prevention and treatment of necrotizing enterocolitis. Frontiers in pediatrics, 10, 859805. https://doi.org/10.3389/fped.2022.859805.
Duess, J. W., Sampah, M. E., Lopez, C. M., Tsuboi, K., Scheese, D. J., Sodhi, C. P., & Hackam, D. J. (2023). Necrotizing enterocolitis, gut microbes, and sepsis. Gut Microbes, 15(1), 2221470. https://doi.org/10.1080/19490976.2023.2221470.
Federici, S., & De Biagi, L. (2019). Long term outcome of infants with NEC. Current pediatric reviews, 15(2), 111-114. https://doi.org/10.2174/1573396315666181130144925.
Handoyo (2018) ‘Necrotizing Enterocolitis pada Neonatus Prematur dan Suplementasi Probiotik’, CDK-264, 45, pp. 391–394.
Johnson-Henry, K. C., Abrahamsson, T. R., Wu, R. Y., & Sherman, P. M. (2016). Probiotics, prebiotics, and synbiotics for the prevention of necrotizing enterocolitis. Advances in nutrition, 7(5), 928-937. https://doi.org/10.3945/an.116.012237.
Kaban, R.K., Kaban, R., Rohsiswatmo, R., Kautsar A., Sutrisno A. A., Hikmahrachim, H. G., & Hardiyanti, N. (2022) ‘Risk factors of necrotizing enterocolitis-related mortality in preterm neonates: a preliminary prospective study’, Paediatrica Indonesiana, 62(3), pp. 186–91. Available at: https://doi.org/10.14238/pi62.3.2022.186-91.
Kaplina, A., Kononova, S., Zaikova, E., Pervunina, T., Petrova, N., & Sitkin, S. (2023). Necrotizing enterocolitis: the role of hypoxia, gut microbiome, and microbial metabolites. International Journal of Molecular Sciences, 24(3), 2471. https://doi.org/10.3390/ijms24032471.
Lopez, C. M., Sampah, M. E. S., Duess, J. W., Ishiyama, A., Ahmad, R., Sodhi, C. P., & Hackam, D. J. (2023, February). Models of necrotizing enterocolitis. In Seminars in perinatology (Vol. 47, No. 1, p. 151695). WB Saunders. https://doi.org/10.1016/j.semperi.2022.151695.
Markel, T. A., Martin, C. A., Chaaban, H., Canvasser, J., Tanner, H., Denchik, H., & Good, M. (2020). New directions in necrotizing enterocolitis with early-stage investigators. Pediatric research, 88(Suppl 1), 35-40. https://doi.org/10.1038/s41390-020-1078-0.
Meister, A. L., Doheny, K. K., & Travagli, R. A. (2020). Necrotizing enterocolitis: It’s not all in the gut. Experimental biology and medicine, 245(2), 85-95. https://doi.org/10.1177/1535370219891971.
Murphy, K., Ross, R. P., Ryan, C. A., Dempsey, E. M., & Stanton, C. (2021). Probiotics, prebiotics, and synbiotics for the prevention of necrotizing enterocolitis. Frontiers in nutrition, 8, 667188. https://doi.org/10.3389/fnut.2021.667188.
Ou, J., Courtney, C. M., Steinberger, A. E., Tecos, M. E., & Warner, B. W. (2020). Nutrition in necrotizing enterocolitis and following intestinal resection. Nutrients, 12(2), 520. https://doi.org/10.3390/nu12020520.
Patel, R. M., Ferguson, J., McElroy, S. J., Khashu, M., & Caplan, M. S. (2020). Defining necrotizing enterocolitis: current difficulties and future opportunities. Pediatric research, 88(Suppl 1), 10-15. https://doi.org/10.1038/s41390-020-1074-4.
Tripathy, P.K. and Nanda, R. (2016) ‘Pediatric Review: International Journal of Pediatric Research Necrotizing Enterocolitis: Probiotics, Prebiotics and Synbiotics for Prevention in Preterm Infants’, p. 11. Available at: www.pediatricreview.in.
Rose, A.T., Saroha, V. and Patel, R.M. (2020) ‘Transfusion-related Gut Injury and Necrotizing Enterocolitis’, Clinics in Perinatology. W.B. Saunders, pp. 399–412. Available at: https://doi.org/10.1016/j.clp.2020.02.002.
Sajankila, N., Wala, S. J., Ragan, M. V., Volpe, S. G., Dumbauld, Z., Purayil, N., ... & Besner, G. E. (2023). Current and future methods of probiotic therapy for necrotizing enterocolitis. Frontiers in pediatrics, 11, 1120459. https://doi.org/10.3389/fped.2023.1120459.
Sajankila, N., Wala, S. J., Ragan, M. V., Volpe, S. G., Dumbauld, Z., Purayil, N., ... & Besner, G. E. (2023). Current and future methods of probiotic therapy for necrotizing enterocolitis. Frontiers in pediatrics, 11, 1120459. https://doi.org/10.3389/fped.2023.1120459.
Sharif, S., Meader, N., Oddie, S. J., Rojas-Reyes, M. X., & McGuire, W. (2020). Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants. Cochrane Database of Systematic Reviews, (10). https://doi.org/10.1002/14651858.CD005496.pub6.
Su, Y., Xu, R. H., Guo, L. Y., Chen, X. Q., Han, W. X., Ma, J. J., ... & Ren, C. J. (2023). Risk factors for necrotizing enterocolitis in neonates: a meta-analysis. Frontiers in pediatrics, 10, 1079894. https://doi.org/10.3389/fped.2022.1079894.
Wu, H., Guo, K., Zhuo, Z., Zeng, R., Luo, Y., Yang, Q., ... & Chen, H. (2022). Current therapy option for necrotizing enterocolitis: Practicalities and challenge. Frontiers in Pediatrics, 10, 954735. https://doi.org/10.3389/fped.2022.954735.
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