Literature Review: Exploration of Bioactive Components of Avicennia marina and Its Biological Activities
DOI:
10.29303/jbt.v24i1b.7987Published:
2024-12-15Downloads
Abstract
Indonesia, as a maritime nation, possesses numerous mangrove ecosystems that have significant potential for exploring their benefits. One species of mangrove that has attracted attention is Avicennia marina, which contains various bioactive compounds. This article aims to provide a comprehensive review of the bioactive components of the Avicennia marina plant and its biological activities, particularly its therapeutic potential and benefits in the pharmaceutical field. We conducted a literature search to find relevant articles in the PubMed, Scopus, and Google Scholar databases using the keywords: plant identification + Avicennia marina; compound identification + Avicennia marina; biological activity + Avicennia marina. The bioactive content from the leaves, fruits, stems, and roots of Avicennia marina has been shown to exhibit antioxidant, antimicrobial, anticancer, and anti-inflammatory effects. This effect is strongly correlated to the presence of active metabolites of triterpenes, terpene alcohols, diterpenes, tannins, dodecanoic acid, octadecanoic acid, phenolic compound, flavonoid, squalene, and phytol. This indicates that Avicennia marina is a promising natural source for further research in the development of a new drug. Our finding further the notion of Avicennia marina as a potential medicinal plant.
Keywords:
Avicennia marina; bioactive compound; biological activity, ethnopharmacology.References
Afshar, A., Khoradmehr, A., Zare, M., Baghban, N., Mohebbi, G.H., Barmak, A., Khatami, M., Mahmudpour, M., Daneshi, A., & Bargahi, A. (2021). Doctoral Dissertation Anticancer Activity of Ethanol and Ethyl Acetate Extracts of Avicennia marina Leaves on Breast, Ovarian and Cervical Cancer Cell Lines, Genentech, South San Francisco, CA, USA.
Al-Mur, B. A. (2021). Biological Activities of Avicennia marina Roots and Leaves Regarding Their Chemical Constituents. Arabian Journal for Science and Engineering, 46(6), 5407–5419. https://doi.org/10.1007/s13369-020-05272-1
Albinhassan, T., Saleh, K., Barhoumi, Z., Alshehri, M.A., Al-Ghazzawi & Adel, M. (2021). Anticancer, Anti-proliferative Activity of Avicennia marina Plant Extracts. Jounal of Cancer Research and Therapeutics. 17 (4): 879-886. DOI: 10.4103/jcrt.JCRT_659_19
Anam, K., Hasibuan, P. A. Z., Lubis, F. R., & Septama, A. W. (2016). Potensi Anti-hiperurisemia dari Avicennia marina Melalui Kandungan Luteolin sebagai Senyawa Anti-inflamasi. Jurnal Fitofarmaka Indonesia, 3(1), 45-52.
Ananthavalli, M., & Karpagam, S. (2017). Antibacterial activity and phytochemical content of Avicennia Marina collected from polluted and unpolluted site. Journal of Medicinal Plants Studies, 5(3), 47–49. https://www.plantsjournal.com/archives/2017/vol5issue3/PartA/5-2-38-706.pdf
Baba, S., Chan, H.T., Oshiro, N., Maxwell, G.S., Inoue T., & Chan, E.W.C. (2016). Botany, Uses, Chemistry and Bioactivities of Mangrove Plants IV: Avicennia marina. ISME/GLOMIS Electronic Journal. 14 (2): 5-6. https://glomis.com/ej/pdf/EJ_14-2.pdf (Accessed on November 6, 2024)
Behbahani, B. A., Tabatabaei Yazdi, F., Shahidi, F., & Riazi, F. (2016). Antifungal Effect of the Aqueous and Ethanolic Avicennia marina Extracts on Alternaria citri and Penicillium digitatum. Zahedan Journal of Research in Medical Sciences, 18(2), 1–6. https://doi.org/10.17795/zjrms-5992
Cerri, F., Giustra, M., Anadol, Y., Tomaino, G., Galli, P., Labra, M., Campone, L. & Colombo, M. (2022). Natural Products from Mangroves: An Overview of the Anticancer Potential of Avicennia marina. 14 (12): 2793. DOI: 10.3390/pharmaceutics14122793
Cucikodana, Y., Malahayati, N., & Widowati, T. W. (2019). Phytochemical Content, Antioxidant And Antibacterial Activity Of Mangrove (Avicennia marina) Leaves Extract. International Journal of Recent Scientific Research, 10(7), 33404–33406. http://dx.doi.org/10.24327/ijrsr.2019.1007.3663
Das, S.K., Patra, J.K., & Thatoi, H. (2015). Antioxidative Response to Abiotic and Biotic Stresses in Mangrove Plants: A Review. International Review of Hydrobiology. 101: 3-19. https://doi.org/10.1002/iroh.201401744
Dawane, V., Pathak, B., & Fulekar, M. H. (2016). HPTLC pattern assessment of Avicennia marina stem and spectrometric analysis of the separated phyto-constituents. Bioscience Biotechnology Research Communications, 9(1), 114–120. https://doi.org/10.21786/bbrc/19.1/17
Devi, A. S., Rajkumar, J., & Jain, S. (2016). Inhibitory Potential Of Avicennia Marina Against Bacterial Pathogens Of Urinary Tract Infection (UTI) From Infected Patients For Health And Sanitation. Int. J. Chem. Sci, 14(2), 1157–1164. https://www.tsijournals.com/articles/inhibitory-potential-of-avicennia-marina-against-bacterial-pathogens-of-urinary-tract-infection-uti-from-infected-patien.pdf
Eldohaji, L.M., Hamoda, A.M., Hamdy, R., & Soliman, S.S.M. (2020). Avicennia marina A Natural Reservoir of Phytopharmaceuticals: Curative Power and Platform of Medicines. Journal of Ethnopharmacology. 263. https://doi.org/10.1016/j.jep.2020.113179
Dharmautama, M., Tetelepta, R., Ikbal, M., & Warti, A. Ea. (2017). Effect of mangrove leaves extract (avicennia marina) concentration to streptococcus mutans and candida albicans growth. Journal of Dentomaxillofacial Science, 2(3), 155. https://doi.org/10.15562/jdmfs.v2i3.648
Esau, L., Sagar, S., Bajic, V.B., & Kaur, M. (2015). Autophagy Inhibition Enhances The Mitochondrial-Mediated Apoptosis Induced by Mangrove (Avicennia marina) Extract in Human Breast Cancer Cells. Eur. J. Med. Plants. 5: 304. DOI: 10.9734/EJMP/2015/14181
Huang, C., Lu, C., Tu, M., Chang J., Chen, Y., Tu, Y., & Huang, H. 2016. Polyphenol-rich Avicennia marina Leaf Extracts Induce Apoptosis in Human Breast and Liver Cancer Cells and in A Nude Mouse Xenograft Model Oncotarget. 7: 35847. DOI: 10.18632/oncotarget.8624
Illian, D.N., Basyuni, M., Wati, R., &Hasibuan P.A.Z. (2018). Polyisoprenoid from Avicennia marina and Avicennia lanata Inhibit WiDr Cells Proliferation. Pharmacogn. 14: 513. DOI: 10.4103/pm.pm_201_18
Maxwell, G.S. (2015). Gaps in Mangrove Science. ISME/GLOMIS Electronic Journal. 13 (5): 18-38. https://glomis.com/ej/pdf/EJ_13-5.pdf (Accessed on November 6, 2024)
Mustopa, A. Z., & Umami, R. N. (2015). Antibacterial Activity Assay Of Mangrove Extracts Against Salmonella Typhi and Listeria Monocytogenes. Jurnal Ilmu Dan Teknologi Kelautan Tropis, 7(2), 603–612. https://doi.org/10.29244/jitkt.v7i2.11029
Nayak, B. K., Janaki, T., & Ganesan, T. (2014). Antimicrobial Activity of Avicennia marina (Forsk) Vierh from Back Water Area of Puducherry, India. International Journal of ChemTech Research, 6(11), 4667–4670. https://www.phytojournal.com/archives/2016/vol5issue1/PartD/5-1-35.pdf
Okla, M. K., Alamri, S. A., Al-Whibi, M. S., et al. (2021). Chemical Composition, Antimicrobial, and Antioxidant Properties of Avicennia marina Plants from Different Habitats. Journal of Pure and Applied Microbiology, 15(2), 835-847. https://doi.org/10.22207/JPAM.15.2.45
Palawe, J. F. P., Cahyono, E., & Karimela, E. J. (2018). Anti-Microbial Activity Of Leave Extract Avicennia marina To Total Microbial and Staphylococcus epidermidis From Fish Pinekuhe. Conference: Masyarakat Pengolahan Hasil Perikanan Indonesia, 1–9. https://doi.org/10.17605/osf.io/td5su
Qurrohman, T., Basyuni, M., Hasibuan P.A.Z. (2020). Polyisoprenoid from Avicennia marina Induces on P13k, Akt1, Mammalian Target of Rapamycin, Egfr, and P53 Gene Expression Using Reverse Transcription-Polymerase Chain Reaction. J. Med. Sci. 8: 146-152. DOI: 10.3889/oamjms.2020.3328
Seedo, K.A. Abido, M.S., Salih, A., Abahussain, A. (2018). Morphophysiological Trits of Gray Mangrove (Avicennia marina (Forsk.) Vierh.) at Different Levels of Soil Salinity. International Journal of Forestry Research. 1. https://doi.org/10.1155/2018/7404907
Setyadi, G., Darmawan, A., & Bahari, A.S. (2023). Mangrove di Mimika-Papua Tengah Indonesia. Aksara Buana, Papua Tengah. ISBN: 978-602-8859-61-5, pp: 57-59.
Sumardi, S., Basyuni, M., & Wati, R. (2018). Antimicrobial activity of polyisoprenoids of sixteen mangrove species from North Sumatra, Indonesia. Biodiversitas Journal of Biological Diversity, 19(4), 1243–1248. https://doi.org/10.13057/biodiv/d190409
Sumardi, S., Masfria, M., Basyuni, M., & Septama, A. W. (2022). Potential of Polyisoprenoid of Mangroves as Antimicrobial and Anticancer: A Bibliometric Analysis. Science and Technology Indonesia, 7(1), 22–28. https://doi.org/10.26554/sti.2022.7.1.22-28
Takarina, N.D., Arif, G.A.F., & Juhriah, S.A. (2018). Phytocemical Contents and Antioxidant Activities of Mangrove (Avicennia marina) Leaves Extract. AIP Conference Proceedings 2023, Volume 2023, Issue 1. https://doi.org/10.1063/1.5064126
Vijayaraj, R., Gnanavel, M., Venkatesan, R., & Kumar, R. (2018). Anti-inflammatory and Antioxidant Activity of Bioactive Compounds from Avicennia marina Leaves. Asian Pacific Journal of Tropical Biomedicine, 8(3), 123-129. https://doi.org/10.1016/j.apjtb.2018.01.012
Zamani Z.,, M., Prajitno, A., & Fadjar, M. (2019). Morphological Characteristics of Bioactive Compounds on Api-Api Mangrove Leaves Extract (Avicennia marina) Based on Leaves Age. Research Journal of Life Science, 6(3), 184–192. https://doi.org/10.21776/ub.rjls.2019.006.03.4
License
Copyright (c) 2024 Cintya Budastra, Tuhfatul Ulya, Selvira Anandia Intan Maulidya, Indra Purnomo, Baiq Risky Wahyu Lisnasari, Lina Permatasari
This work is licensed under a Creative Commons Attribution 4.0 International License.
Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.
The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.
Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.
