Hypothyroidism with Myxedema Coma Complications: A Review of Articles during November 2024

Ni Made Ayu Mas Sista Paramadinda; Siti Zahroni Aulia; Fadila Rahmawati; Alana Akmal Yuar; Perlin Nigel Valencia; Annisa Salsabila Qadri; Yaskuna Urfi Rabbani; Baiq Sheila Oktalia Hakim; Rizki Yolanda; Galang Edi Wibawa

doi:10.29303/jbt.v25i3.9984

Hypothyroidism with Myxedema Coma Complications: A Review of Articles during November 2024

Authors

Ni Made Ayu Mas Sista Paramadinda , Siti Zahroni Aulia , Fadila Rahmawati , Alana Akmal Yuar , Perlin Nigel Valencia , Annisa Salsabila Qadri , Yaskuna Urfi Rabbani , Baiq Sheila Oktalia Hakim , Rizki Yolanda , Galang Edi Wibawa

DOI:

10.29303/jbt.v25i3.9984

Published:

2025-08-20

Issue:

Vol. 25 No. 3 (2025): Juli-September

Keywords:

Hypothyroidism, Myxedema coma, Thyroid hormone

Articles

Downloads

How to Cite

Paramadinda, N. M. A. M. S., Aulia, S. Z., Rahmawati, F., Yuar, A. A., Valencia, P. N., Qadri, A. S., … Wibawa, G. E. (2025). Hypothyroidism with Myxedema Coma Complications: A Review of Articles during November 2024. Jurnal Biologi Tropis, 25(3), 4528–4537. https://doi.org/10.29303/jbt.v25i3.9984

Download Citation

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Abstract

Hypothyroidism is a condition characterized by decreased thyroid hormone production due to impaired thyroid or hypothalamic-pituitary gland function. Hypothyroidism is more common in women due to iodine deficiency. This condition can also be caused by autoimmune disorders. Symptoms of hypothyroidism vary, from mild, with few or no symptoms, to severe. Most symptoms are variable, vague, and delayed in onset. This paper aims to provide a comprehensive understanding of the diagnosis and management of hypothyroidism complicated by myxedema coma. The writing method used in this literature review is references from various Indonesian and English-language literature. The literature search was conducted during November 2024, with 10 articles obtained. The review results showed that severe and uncontrolled hypothyroidism can lead to myxedema coma. Myxedema coma is a condition characterized by decreased consciousness accompanied by generalized edema. This condition frequently associated with hypothermia and hyponatremia. Myxedema coma can be diagnosed using a scoring system. Therefore, an understanding of how to diagnose and properly manage hypothyroidism with complications of myxedema coma is needed for early detection so as not to worsen the patient's prognosis.

References

American Thyroid Association (2019). Hypothyroidism. Falls Church: American Thyroid Association. Available at: https://www.thyroid.org/wp-content/uploads/patients/brochures/Hypothyroidism_web_booklet.pdf.

Anggraini, D., & Fharel, M. (2025). Peran Thyroid Stimulating Hormone pada Bayi Baru Lahir. Scientific Journal, 4(1), 23-29. https://doi.org/10.56260/sciena.v4i1.188

Bereda, G. (2023). Definition, causes, pathophysiology, and management of hypothyroidism. Mathews Journal of Pharmaceutical Science, 7(1), 1-5. https://doi.org/10.30654/MJPS.10014

Chaker, L., Razvi, S., Bensenor, I. M., Azizi, F., Pearce, E. N., & Peeters, R. P. (2022). Publisher correction: hypothyroidism. Nature Reviews. Disease Primers, 8(1). https://doi.org/10.1038/s41572-022-00357-7.

Cotama, C. R., & Yulistiani, Y. (2025). Pola Pengobatan Badai Tiroid pada Pasien Lanjut Usia. Jurnal Penelitian Kesehatan" SUARA FORIKES"(Journal of Health Research" Forikes Voice"), 16(1), 330-342. http://dx.doi.org/10.33846/sf16166

Decroli, E., & Kam, A. (2017). Dampak Klinis Thyroid-Stimulating Hormone. Jurnal Kesehatan Andalas, 6(1), 222-230. https://doi.org/10.25077/jka.v6i1.674

Elshimy G, Chippa V, Correa R. Myxedema. [Diperbarui 14 Agustus 2023]. Dalam: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing.

Kelgaonkar, A.M. (2022) ‘Pharmacological and Non-Pharmacological Strategies for Managing Hypothyroidism. International Journal of Creative Research Thoughts, 10(1), pp. 479–485. www.ijcrt.org.

Mathew, V., Misgar, R. A., Ghosh, S., Mukhopadhyay, P., Roychowdhury, P., Pandit, K., ... & Chowdhury, S. (2011). Myxedema coma: a new look into an old crisis. Journal of thyroid research, 2011(1), 493462. https://doi.org/10.4061/2011/493462.

Mukhlisatunnafsi, L. (2024). Hipotiroid Kongenital: Diagnosis, Manifestasi Klinis, Dan Penatalaksanaan. Jurnal Medika Hutama, 5(02 Januari), 3832-3841. https://jurnalmedikahutama.com/index.php/JMH/article/view/684

Mutalazimah, M., Mulyono, B., Murti, B., & Azwar, S. (2017). Kajian patofisiologis gejala klinis dan psikososial sebagai dampak gangguan fungsi tiroid pada wanita usia produktif. Jurnal Kesehatan, 6(1), 1-14. https://journals.ums.ac.id/jk/article/view/5506

Muthmainnah, A., & Rustam, R. P. (2024). Laporan Kasus Hipertiroidisme pada Kehamilan: Hasil Ibu dan Neonatal. JOMIS (Journal of Midwifery Science), 8(1), 61-70.

Patil, N.et al. (2024). Hypothyroidism. StatPearls Publishing. Available at: https://www.ncbi.nlm.nih.gov/books/NBK519536/

Suryantini, N. K. M., Putri, L. L., Salim, B. H., Mawaddah, A., & Triani, E. (2024). Gangguan Hormon Tiroid: Hipotiroidisme. Jurnal Ilmu Kedokteran dan Kesehatan, 11(6), 1227-1234.

Talha, A., Houssam, B., & Brahim, H. (2020). Myxedema coma: a review. European Journal of Medical and Health Sciences, 2(3). doi:https://doi.org/10.24018/ejmed.2020.2.3.349.

Tarigan, M. B., & Siahaan, J. M. (2021). Diagnosis Dini Dan Tatalaksana Hipotiroid. Majalah Ilmiah Methoda, 11(2), 145-148. https://doi.org/10.46880/methoda.vol11no2.pp145-148.

Wenilia, R. (2024). Hypothyroid and Heart Disease. Jurnal Medika Hutama, 6(01 Oktober), 4084-4095. https://jurnalmedikahutama.com/index.php/JMH/article/view/720

Wiersinga, W.M. (2021) ‘Myxedema and Coma (Severe Hypothyroidism)’, Endotext [Preprint]. Available at: http://www.ncbi.nlm.nih.gov/pubmed/25905238.

Yurizali, B., & Adhyka, N. (2024). Profil Tingkat Hormon Stimulasi Tiroid (TSH) dan Kondisi Kesehatan dalam Studi Populasi Dewasa: Analisis Data menggunakan SPSS. Jurnal Kedokteran Dan Kesehatan, 20(2), 124-137. https://doi.org/10.24853/jkk.20.2.124-137

License

Copyright (c) 2025 Ni Made Ayu Mas Sista Paramadinda, Siti Zahroni Aulia, Fadila Rahmawati, Alana Akmal Yuar, Perlin Nigel Valencia, Annisa Salsabila Qadri, Yaskuna Urfi Rabbani, Baiq Sheila Oktalia Hakim, Rizki Yolanda, Galang Edi Wibawa

This work is licensed under a Creative Commons Attribution 4.0 International License.

Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.

The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.

Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.

Most read articles by the same author(s)

Galang Edi Wibawa, Alana Akmal Yuar, Fadila Rahmawati, Perlin Nigel Valencia Maurae, Baiq Sheila Oktalia Hakim, Muhammad Rizky Yolanda Bisa, Ni Made Ayu Mas Sista Paramadinda, Siti Zahroni Aulia, Yaskuna Urfi Rabbani, Effectiveness of Sunscreen in Preventing Skin Problems , Jurnal Biologi Tropis: Vol. 25 No. 4 (2025): Oktober-Desember
Sandia Anggun Rahmadinna, Alana Akmal Yuar, Aulia Putri Musyafa, Excell Defry Hardiant, Baiq Ghefira Rojwani Putri, Atriska Citra Muliana, Septy Rianty Putri Salsabila, Sania Tresna Ningrum, Ahmad Wahyu Narendra, Yasmine Najla Ramadhania, Philip Habib, Literature Study: Primary Immunodeficiency , Jurnal Biologi Tropis: Vol. 25 No. 4 (2025): Oktober-Desember
Baiq Sheila Okthalia Hakim, Fadila Rahmawati, Alana Akmal Yuar, Febi Jian Setiasari, Nafisya Ayu Evana, Moh Rizky Yolanda B.S, Diagnosis and Management of Cholangiocarcinoma (CCA) , Jurnal Biologi Tropis: Vol. 25 No. 4 (2025): Oktober-Desember
Perlin Nigel Valencia Maurae, Baiq Sheila Oktalia Hakim, Alana Akmal Yuar, Brain Arteriovenous Malformations: Diagnostic Challenges and Therapeutic Options , Jurnal Biologi Tropis: Vol. 25 No. 4 (2025): Oktober-Desember
Baiq Syarifaturrayyan Maharani, Nanggi Qoriatul Febriana, Padmi Kartika Sari, Baiq Zaskia Maudina, Baiq Sheila Oktalia Hakim, Aortic Stenosis Review: Pathophysiology, Clinical Symptoms, and Key Diagnostic Signs , Jurnal Biologi Tropis: Vol. 25 No. 4 (2025): Oktober-Desember
Alana Akmal Yuar, Comprehensive Review of Antihypertensive Therapy: Pathophysiology, Diagnosis, and Management , Jurnal Biologi Tropis: Vol. 25 No. 4 (2025): Oktober-Desember
Khansa Aulia Sabrina, Fadila Rahmawati, Hasna Tazkia Aghni, Chivan Agustinus Siregar, Diphtheria and Pertussis: A Literature Review of Two Preventable Infectious Diseases , Jurnal Biologi Tropis: Vol. 25 No. 4 (2025): Oktober-Desember
Shira Shalsabina Shafitri, Muhammad Rafly Adrian Sugiono, Andi Frieskha Naurah Paradiesta, Siti Zahroni Aulia, Janiya Abdila Ilmiah, Ilsa Hunaifi, Impact of Coma Duration on Functional Outcomes After Septic Encephalopathy: A Literature Review , Jurnal Biologi Tropis: Vol. 25 No. 4a (2025): Special Issue
Ihza Namira Athalia, Alana Akmal Yuar, Pseudocyesis: From Psycho-Social Conflict to Somatic Reality, A Literature Review , Jurnal Biologi Tropis: Vol. 25 No. 4 (2025): Oktober-Desember
Annisa Salsabila Qadri, Siti Zahroni, Gede Naradhea, Perlin Nigel Valencia Maurae, Rizky Yolanda, Shaffany Mahasuary, Aqilla Nasywa Nabila, Comparison of Effectiveness of Peroral Endoscopic Myotomy-Transoral Incisionless Fundoplication (POEM-TIF) Compared with Laparoscopic Heller Myotomy (LHM) in the Management of Achalasia , Jurnal Biologi Tropis: Vol. 25 No. 4 (2025): Oktober-Desember

Hypothyroidism with Myxedema Coma Complications: A Review of Articles during November 2024

Authors

DOI:

Published:

Issue:

Keywords:

Articles

Downloads

How to Cite

Downloads

Metrics

Abstract

References

License

Most read articles by the same author(s)

Similar Articles

Menu

Manuscript Template

visitor

Keywords

Mitra Kerja sama

Open Access Journals

Contact Us

Information

Share & Follow