Determination of flavonoid levels of Macaranga gigantea and its activity as antioxidants

Authors

Samsul Hadi , Dian Ekowati , Amalia Khairunnisa

DOI:

10.29303/jpm.v18i1.4054

Published:

2023-01-31

Issue:

Vol. 18 No. 1 (2023): January 2023

Keywords:

Antioxidant, Flavonoid, M. gigantea, DPPH, AlCl3

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Hadi, S., Ekowati, D. ., & Khairunnisa, A. . (2023). Determination of flavonoid levels of Macaranga gigantea and its activity as antioxidants. Jurnal Pijar Mipa, 18(1), 93–97. https://doi.org/10.29303/jpm.v18i1.4054

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Abstract

One of the ways to prevent generative diseases is by using natural antioxidant compounds. The flavonoid compounds in the flower parts of M. gigantea have a role in antioxidants. Thus the study aimed to test the antioxidant activity and flavonoid levels of M. gigantea flowers. The antioxidant test was carried out by UV-vis spectrophotometry using 2,2-diphenyl-1-picrylhydrazyl and flavonoid assay using 10% aluminum chloride and potassium acetate, both tests using quercetin as a comparison. The results of this test obtained IC50 antioxidants 145,725 ± 3.858 ppm, and flavonoids were 1,860 ± 0.007% w/w eq quercetin. The conclusion from the experiments that have been carried out is that M. gigantea flowers have moderate antioxidant abilities.

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Author Biographies

Samsul Hadi, Departement of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Lambung Mangkurat

Dian Ekowati, Departement of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Lambung Mangkurat

Amalia Khairunnisa, Departement of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Lambung Mangkurat

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