Test The Activity of Microgel Preparations from Skin Extract Jengkol (Pithecellobium lobatum Benth) on The Healing of Cut Wounds in White Rats (Rattus novergicus)

Rezza Fikrih Utama; Renni Paska Situmorang; Fahri Husaini; Muhammad Andry; Fitria Eka Resti Wijayanti

doi:10.29303/jbt.v24i3.7609

Test The Activity of Microgel Preparations from Skin Extract Jengkol (Pithecellobium lobatum Benth) on The Healing of Cut Wounds in White Rats (Rattus novergicus)

Authors

Rezza Fikrih Utama , Renni Paska Situmorang , Fahri Husaini , Muhammad Andry , Fitria Eka Resti Wijayanti

DOI:

10.29303/jbt.v24i3.7609

Published:

2024-09-06

Issue:

Vol. 24 No. 3 (2024): July - September

Keywords:

Cut wounds, jackfruit skin extract, microgel.

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Utama, R. F., Situmorang, R. P., Husaini, F., Andry, M., & Wijayanti, F. E. R. (2024). Test The Activity of Microgel Preparations from Skin Extract Jengkol (Pithecellobium lobatum Benth) on The Healing of Cut Wounds in White Rats (Rattus novergicus). Jurnal Biologi Tropis, 24(3), 812–817. https://doi.org/10.29303/jbt.v24i3.7609

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Abstract

The skin is the largest and heaviest organ in the body, covering its outer surface. Wounds are often experienced by everyone due to the loss of epithelial integrity of the skin. Jengkol fruit skin is useful as a burn medicine and antiseptic to test the activity of microgel preparations from jengkol skin extract (Pithecellobium lobatum Benth) on healing cuts in white rats (Rattus novergicus). This study was a true experimental, post test control only design using the Completely Randomized Design (CRD) statistical method. The data were analyzed statistically using SPSS and continued with ANOVA test to see significant differences between the 5 treatment groups. The results of the study obtained microgel preparations that had activity for healing cuts on the backs of white rats, namely the F3 preparation with a concentration of 15% jengkol skin extract with wound observation for 12 days. In conclusion, cuts on the backs of white rats can be healed with jengkol skin extract.

References

Asadi, S. Y., Parsaei, P., Karimi, M., Ezzati, S., Zamiri, A., Mohammadizadeh, F., & Rafieian-Kopaei, M. (2013). Effect of green tea (Camellia sinensis) extract on healing process of surgical wounds in rat. International Journal of Surgery, 11(4), 332-337. 10.1016/j.ijsu.2013.02.014

Daud, N. S., & Suryanti, E. (2017). Formulasi Emulgel Antijerawat Minyak Nilam (Patchouli oil) Menggunakan Tween 80 dan Span 80 sebagai Pengemulsi dan HPMC sebagai Basis Gel. Jurnal Mandala Pharmacon Indonesia, 3(02), 90-95. https://doi.org/10.35311/jmpi.v3i02.3

Depkes. (1995). Farmakope Indonesia edisi V 1995. Jakarta: Departemen Kesehatan Republik Indonesia.

Depkes. (2000). Farmakope Indonesia edisi V 1995. Jakarta: Departemen Kesehatan Republik Indonesia.

Hawilla, A., Zulkarnain, A. K., & Lukitaningsih, E. (2023). Stabilitas dan Sifat Fisik Sediaan Mikroemulgel Resveratrol Sebagai Tabir Surya dan Antiaging Secara In Vitro. Majalah Farmaseutik, 155-163. https://doi.org/10.22146/farmaseutik.v19i2.83497

Ilma, M., Rismawati, E., & Syafnir, L. (2016). Uji Aktivitas Antioksidan Ekstrak Dan Fraksi Kulit Buah Jengkol ( Archidendron jiringa ( Jeck ) Nielsen Dengan Metode Peredaman Radikal Bebas DPPH. Prosiding Farmasi, 2(1), 161–166. https://karyailmiah.unisba.ac.id/index.php/farmasi/article/viewFile/3123/pdf

Indratno, S. H. A., Debora, P. C., Fitri, N. K., Ambarati, T., Zahra, A. A., & Mierza, V. (2023). Artikel Review: Analisis Ekstraksi dan Identifikasi Senyawa Saponin pada Tumbuhan Mahkota Dewa (Phaleria macrocarpa). Jurnal Pendidikan dan Konseling (JPDK), 5(1), 386-394. https://doi.org/10.31004/jpdk.v5i1.10948

Irianto, I. D., Purwanto, & Mardan, M. T. (2020). Aktivitas Antibakteri dan Uji Sifat Fisik Sediaan Gel Dekokta Sirih Hijau (Piper betle L.) Sebagai Alternatif Pengobatan Mastitis Sapi. Majalah Farmaseutik, 202-210. https://doi.org/10.22146/farmaseutik.v16i2.53793

Kumar, V., R. S. Cotran, dan S. L. Robbins. (2007). Buku Ajar Patologi Edisi 7.

Penerbit Buku Kedokteran EGC. Jakarta

Malini, D. M., Madinah, & Kamilawati, F. (2017). Uji potensi sediaan salep ekstrak etanol kulit buah jengkol untuk mempercepat penutupan luka pada kulit mencit model diabet . PROS SEM NAS MASY BIODIV INDON, 205-210. 10.13057/psnmbi/m030207

Meilia, A., Junaedi, C., & Rezaldi, F. (2022). Formulasi Salep Ekstrak Etanol Daun Cocor Bebek (Kalanchoe pinnata (Lam.) Pers) Untuk Penyembuhan Luka Sayat Pada Tikus Putih. Jurnal Medika & Sains [J-MedSains], 2(1), 9-19. https://doi.org/10.30653/medsains.v2i1.99

Moenadjat, Y. (2023). Penyembuhan Luka: Aspek Seluler dan Biomolekuler.

Nijveldt, R. J., Van Nood, E. L. S., Van Hoorn, D. E., Boelens, P. G., Van Norren, K., & Van Leeuwen, P. A. (2001). Flavonoids: a review of probable mechanisms of action and potential applications. The American journal of clinical nutrition, 74(4), 418-425. 10.1093/ajcn/74.4.418

Perdanakusuma, D. S. (2007). Natomi Fisiologi Kulit Dan Penyembuhan Luka. Plastic Surgery Departement Airlangga University School of Medicine – Dr. Soetomo General Hospital. Surabaya: Plastic Surgery Departement..

Priani, S. E., Dewi, W. K., & Gadri, A. (2018). Formulasi sediaan mikroemulsi gel anti jerawat mengandung kombinasi minyak jinten hitam (Nigella sativa L.) dan minyak zaitun (Olea europaea L.). Jurnal Ilmiah Farmasi, 57-64. https://doi.org/10.26874/kjif.v6i2.143

Primadina, N., Basori, A., & Perdanakusuma, D. S. (2019). Proses penyembuhan luka ditinjau dari aspek mekanisme seluler dan molekuler. Qanun Medika-Medical Journal Faculty of Medicine Muhammadiyah Surabaya, 3(1), 31-43. https://doi.org/10.30651/jqm.v3i1.2198

Rezaldi, F., Khodijah, S., & Sumarlin, U. S. (2022). Formulasi dan Uji Efektivitas Sediaan Sirup Ekstrak Daun Kacapiring (Gardenia jasminoides J. Ellis) Sebagai Antipiretik Terhadap Mencit (Mus musculus L) YANG DI INDUKSI VAKSIN DPT. Jurnal Biogenerasi, 7(1), 1-16. https://doi.org/10.30605/biogenerasi.v7i1.1555

Rizal, M., Yusransyah, Y., & Stiani, S. N. (2016). Uji aktivitas antidiare ekstrak etanol 70% kulit buah jengkol (Archidendron pauciflorum (Benth.) IC Nielsen) terhadap mencit jantan yang diinduksi Oleum ricini. Jurnal Ilmiah Manuntung, 2(2), 131-136. https://doi.org/10.51352/jim.v2i2.57

Usman, Y., & Panaungi, A. N. (2024). Uji Aktivitas Salep Ekstrak Etanol Daun Ubi Jalar Ungu (Ipomoea batatas L.) untuk Luka Bakar pada Kelinci. Jurnal MIPA, 13(2), 99-104. https://doi.org/10.35799/jm.v13i2.56352

Wartono, W., Mazmir, M., & Aryani, F. (2021). Analisis Fitokimia Dan Aktivitas Antioksidan Pada Kulit Buah Jengkol (Pithecellobium Jiringga). Buletin Poltanesa, 22(1), 80-85. https://doi.org/10.51967/tanesa.v22i1.472

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Test The Activity of Microgel Preparations from Skin Extract Jengkol (Pithecellobium lobatum Benth) on The Healing of Cut Wounds in White Rats (Rattus novergicus)

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