Japanese Papaya (Cnidoscolus aconitifolius): An Integrated Biological System with Mechanism-Based Utilization

Prapti Sedijani; Mahrus Mahrus; Dewa Ayu Citra Rasmi; Kusmiyati Kusmiyati; Khaerudin Khaerudin

doi:10.29303/jbt.v25i4a.11234

Japanese Papaya (Cnidoscolus aconitifolius): An Integrated Biological System with Mechanism-Based Utilization

Authors

Prapti Sedijani , Mahrus , Dewa Ayu Citra Rasmi , Kusmiyati , Khaerudin

DOI:

10.29303/jbt.v25i4a.11234

Published:

2025-12-31

Issue:

Vol. 25 No. 4a (2025): Special Issue

Keywords:

Cnidoscolus aconitifolius, systems biology, Bological activitiest, plant enzyme, potential use

Articles

Downloads

How to Cite

Sedijani, P., Mahrus, M., Rasmi, D. A. C., Kusmiyati, K., & Khaerudin, K. (2025). Japanese Papaya (Cnidoscolus aconitifolius): An Integrated Biological System with Mechanism-Based Utilization . Jurnal Biologi Tropis, 25(4a), 805–810. https://doi.org/10.29303/jbt.v25i4a.11234

Download Citation

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Abstract

Cnidoscolus aconitifolius (Japanese papaya or chaya) is a tropical plant from the Euphorbiaceae family known for its high nutritional value and diverse biological activities. Several studies have reported antioxidant, antimicrobial, and other biological properties, suggesting the involvement of complex molecular systems. This article presents a conceptual literature review using a systems biology approach to understand Japanese papaya as an integrated biological system in which nutritional components, secondary metabolites, and enzymatic activities interact. By positioning hydrolytic enzyme systems as the central mechanism, this review discusses the potential utilization of Japanese papaya as a biological resource and as a basis for the development of functional derivative products, including biomolecular hydrolysates. Possible applications in mechanism-based bioconversion processes are also briefly addressed.

References

Adeyemi, D. O., et al. (2010). Biological activities of Euphorbiaceae plants: a review. African Journal of Biotechnology, 9(38), 6226–6232.

Agrawal, A. A., et al. (2012). Plant defense syndromes. Trends in Ecology & Evolution, 27(4), 206–215.

Barrett, A. J., et al. (2012). Proteolytic enzymes: Nomenclature and classification. Biochemical Journal, 441, 1–16.

Cowan, M. M. (1999). Plant products as antimicrobial agents. Clinical Microbiology Reviews, 12(4), 564–582.

Daliri, E. B. M., et al. (2017). Bioactive peptides: A review on production and functionality. Trends in Food Science & Technology, 59, 1–15.

Duarte, J., et al. (2004). Enzymatic hydrolysis of protein waste. Bioresource Technology, 91, 229–236.

Ernesto, M., et al. (2002). Cyanogenic glycosides in plants. Phytochemistry, 60, 659–669.

Fasuyi, A. O. (2007). Nutritional potentials of leaf protein concentrates. African Journal of Biotechnology, 6(20), 2293–2297.

Fitzgerald, R. J., & Meisel, H. (2000). Milk protein-derived peptides. British Journal of Nutrition, 84(S1), S33–S37.

Ghaly, A. E., et al. (2013). Fish processing wastes as a potential source of proteins. American Journal of Environmental Sciences, 9(1), 27–49.

Hartmann, R., & Meisel, H. (2007). Food-derived peptides with biological activity. Current Opinion in Biotechnology, 18, 163–169.

Ibrahim, M. A., et al. (2014). Phytochemical and biological studies of Cnidoscolus species. Journal of Medicinal Plants Research, 8(6), 281–287.

Jørgensen, K., et al. (2005). Cyanogenic glucosides in plants. Phytochemistry, 66, 161–180.

Kitano, H. (2002). Systems biology: A brief overview. Science, 295, 1662–1664.

Kitano, H. (2007). Towards a theory of biological robustness. Molecular Systems Biology, 3, 137.

Korhonen, H., & Pihlanto, A. (2006). Bioactive peptides: Production and functionality. International Dairy Journal, 16, 945–960.

Kristinsson, H. G., & Rasco, B. A. (2000). Fish protein hydrolysates: Production, biochemical, and functional properties. Critical Reviews in Food Science and Nutrition, 40(1), 43–81.

Kuti, J. O., & Torres, E. S. (1996). Nutritional and functional properties of tree spinach (Cnidoscolus aconitifolius). Progress in New Crops.

López-García, B., et al. (2016). Antimicrobial peptides in plants. Journal of Experimental Botany, 67(11), 3211–3224.

Martínez-Villaluenga, C., & Hernández-Ledesma, B. (2017). Bioactive peptides in food systems. Food & Function, 8, 244–256.

Morone, P., & Gonella, F. (2019). Evolution of the circular economy concept. Journal of Cleaner Production, 229, 440–453.

Oyeyemi, I. T., et al. (2018). Nutritional and safety evaluation of chaya leaves. Journal of Food Safety, 38, e12454.

Rawlings, N. D., & Salvesen, G. (2013). Handbook of Proteolytic Enzymes. Academic Press.

Ross-Ibarra, J., Molina-Cruz, A., & Sánchez-Vargas, I. (2003). Chaya (Cnidoscolus aconitifolius): A potential new crop for the tropics. Economic Botany, 57(4), 513–527.

Ryan, C. A. (1990). Protease inhibitors in plants. Annual Review of Phytopathology, 28, 425–449.

Udenigwe, C. C., & Aluko, R. E. (2012). Food protein-derived bioactive peptides. Journal of Food Science, 77(1), R11–R24.

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Jurnal Biologi Tropis is licensed under a Creative Commons Attribution 4.0 International License.

The copyright of the received article shall be assigned to the author as the owner of the paper. The intended copyright includes the right to publish the article in various forms (including reprints). The journal maintains the publishing rights to the published articles.

Authors are permitted to disseminate published articles by sharing the link/DOI of the article at the journal. Authors are allowed to use their articles for any legal purposes deemed necessary without written permission from the journal with an acknowledgment of initial publication to this journal.

Most read articles by the same author(s)

Sekar Partiwi, Agil Al Idrus, Lalu Zulkifli, Mahrus, Prapti Sedijani, Isolation and Molecular Characterization of Brotowali (Tinospora crispa) Rhizosphere Bacteria Producing Siderophore from Dry Lands of Lombok Island , Jurnal Biologi Tropis: Vol. 23 No. 2 (2023): Special Issue
Lidia Zindarti Nurmia, Karnan Karnan, Mahrus Mahrus, Reproductive Aspects of Lemuru Fish (Sardinella Lemuru) Landed at PPI Tanjung Luar East Lombok as Enrichment Material for Zoology Subjects , Jurnal Biologi Tropis: Vol. 23 No. 1 (2023): January - March
Zidna Ilma Nafi'ah, Prapti Sedijani, Lalu Japa, The Effect of Liquid Organic Fertilizer (LOF) from Rotten Fruit on the Growth of Chili Pepper Plants (Capsicum frutescens L.) , Jurnal Biologi Tropis: Vol. 25 No. 4 (2025): Oktober-Desember
Yolanda Sabrina, Prapti Sedijani, Mohammad Liwa Ilhamdi, I Putu Artayasa, The Effect of Lemongrass Plant Extract (Cymbopogon nardus (L.) Rendle) on The Number of Fruit Flies (Bactrosera sp) Catches , Jurnal Biologi Tropis: Vol. 25 No. 3 (2025): Juli-September
Yulia Ningsih, Lalu Zulkifli, Mahrus Mahrus, Isolation of endophytic bacteria from cashew root and its ability as phosphate solubilizing and IAA-producing bacteria , Jurnal Biologi Tropis: Vol. 22 No. 3 (2022): July - September
Khairuddin Khairuddin, M. Yamin, Kusmiyati Kusmiyati, Content of The Heavy Metal Cd in Tilapia Fish from Rawa Taliwang Lake , Jurnal Biologi Tropis: Vol. 24 No. 2 (2024): April - Juni
Prapti Sedijani, Maskatur Rahmi, Lalu Japa , Miko Eniarti, Penambahan Kulit Kacang Tanah pada Medium Jamur Menambah Berat Kering Jamur Tiram Putih , Jurnal Biologi Tropis: Vol. 23 No. 3 (2023): July - September
Siti Nur Isnaini Hidayati, Lalu Zulkifli, Prapti Sedijani, Dewa Ayu Citra Rasmi, Antagonistic Test of Endophytic Bacteria of Chili Pepper Roots Producing Siderophores and Hydrolase Enzymes against Plant Pathogenic Bacteria Ralstonia Solanacearum , Jurnal Biologi Tropis: Vol. 24 No. 4 (2024): Oktober - Desember
Prapti Sedijani, Peran Trehalose Metabolisme Sepanjang Masa Kehidupan Tanaman , Jurnal Biologi Tropis: Jurnal Biologi Tropis. Vol.14 No. 2 Desember 2014
Marwa Azzahra, I Wayan Merta, Kusmiyati Kusmiyati, The Effect of Kepel Fruit Extract on The Number of Spermatogenic Cells in Mice (Mus musculus) , Jurnal Biologi Tropis: Vol. 23 No. 4 (2023): October - December

<< < 1 2 3 4 5 6 7 8 > >>

Japanese Papaya (Cnidoscolus aconitifolius): An Integrated Biological System with Mechanism-Based Utilization

Authors

DOI:

Published:

Issue:

Keywords:

Articles

Downloads

How to Cite

Downloads

Metrics

Abstract

References

License

Most read articles by the same author(s)

Similar Articles

Menu

Manuscript Template

visitor

Keywords

Mitra Kerja sama

Open Access Journals

Contact Us

Information

Share & Follow